Mediator tail subunits can form amyloid-like aggregatesin vivoand affect stress response in yeast

The cell biology of prion-like spread of protein aggregates: mechanisms and implication in neurodegeneration

(2015) Maddalena Costanzo et al.   BIOCHEMICAL JOURNAL

Redefining the modular organization of the core Mediator complex

(2014) Xuejuan Wang et al.   CELL RESEARCH

Kin28 regulates the transient association of Mediator with core promoters

(2014) Célia Jeronimo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Suppression of Mediator is regulated by Cdk8-dependent Grr1 turnover of the Med3 coactivator

(2014) D. Gonzalez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential Genetic Interactors of SIR2 Required for Spatial Sequestration and Asymmetrical Inheritance of Protein Aggregates

(2014) Jia Song et al.   PLoS Genetics

Mediator Recruitment to Heat Shock Genes Requires Dual Hsf1 Activation Domains and Mediator Tail Subunits Med15 and Med16

(2013) Sunyoung Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The story of stolen chaperones

(2013) Irina L Derkatch et al.   Prion

The multitalented Mediator complex

(2013) Jonas O.P. Carlsten et al.   TRENDS IN BIOCHEMICAL SCIENCES

Blessings in disguise: biological benefits of prion-like mechanisms

(2013) Gregory A. Newby et al.   TRENDS IN CELL BIOLOGY

Mediator Promotes CENP-A Incorporation at Fission Yeast Centromeres

(2012) J. O. Carlsten et al.   MOLECULAR AND CELLULAR BIOLOGY

Mediator Complex Regulates Alternative mRNA Processing via the MED23 Subunit

(2012) Yan Huang et al.   MOLECULAR CELL

Prions are a common mechanism for phenotypic inheritance in wild yeasts

(2012) Randal Halfmann et al.   NATURE

A Yeast Prion, Mod5, Promotes Acquired Drug Resistance and Cell Survival Under Environmental Stress

(2012) G. Suzuki et al.   SCIENCE

Identification of Human Proteins That Modify Misfolding and Proteotoxicity of Pathogenic Ataxin-1

(2012) Spyros Petrakis et al.   PLoS Genetics

Distinct role of Mediator tail module in regulation of SAGA-dependent, TATA-containing genes in yeast

(2011) Suraiya A Ansari et al.   EMBO JOURNAL

Histone modifications influence mediator interactions with chromatin

(2011) Xuefeng Zhu et al.   NUCLEIC ACIDS RESEARCH

The Stress Response Factors Yap6, Cin5, Phd1, and Skn7 Direct Targeting of the Conserved Co-Repressor Tup1-Ssn6 in S. cerevisiae

(2011) Sean E. Hanlon et al.   PLoS One

Newly identified prions in budding yeast, and their possible functions

(2011) Emily T. Crow et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae

(2011) Katsunori Yoshikawa et al.   YEAST

Prion Formation and Polyglutamine Aggregation Are Controlled by Two Classes of Genes

(2011) Anita L. Manogaran et al.   PLoS Genetics

Hsp90 and Environmental Stress Transform the Adaptive Value of Natural Genetic Variation

(2010) D. F. Jarosz et al.   SCIENCE

A Systematic Survey Identifies Prions and Illuminates Sequence Features of Prionogenic Proteins

(2009) Simon Alberti et al.   CELL

Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3

(2008) Krista D Meyer et al.   EMBO JOURNAL

Mediator Subunit Gal11p/MED15 Is Required for Fatty Acid-dependent Gene Activation by Yeast Transcription Factor Oaf1p

(2008) Jitendra K. Thakur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mediator Links Epigenetic Silencing of Neuronal Gene Expression with X-Linked Mental Retardation

(2008) Ning Ding et al.   MOLECULAR CELL

Malleable Machines in Transcription Regulation: The Mediator Complex

(2008) Ágnes Tóth-Petróczy et al.   PLoS Computational Biology