RNAi revised - target mRNA-dependent enhancement of gene silencing

Structural basis for microRNA targeting

(2014) N. T. Schirle et al.   SCIENCE

Molecular Mechanisms of RNA Interference

(2013) Ross C. Wilson et al.   Annual Review of Biophysics

Computational identification of biologically functional non-hairpin GC-helices in human Argonaute mRNA

(2013) Simon Dornseifer et al.   BMC BIOINFORMATICS

Minimal mechanistic model of siRNA-dependent target RNA slicing by recombinant human Argonaute 2 protein

(2013) A. Deerberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparison of reverse transcription–quantitative polymerase chain reaction methods and platforms for single cell gene expression analysis

(2012) Bridget C. Fox et al.   ANALYTICAL BIOCHEMISTRY

Argonaute Divides Its RNA Guide into Domains with Distinct Functions and RNA-Binding Properties

(2012) Liang Meng Wee et al.   CELL

The Structure of Human Argonaute-2 in Complex with miR-20a

(2012) Elad Elkayam et al.   CELL

Quantitative functions of Argonaute proteins in mammalian development

(2012) D. Wang et al.   GENES & DEVELOPMENT

Expression and function of micro RNAs in immune cells during normal or disease state

(2012) Esmerina Tili et al.   International Journal of Medical Sciences

Structure of yeast Argonaute with guide RNA

(2012) Kotaro Nakanishi et al.   NATURE

The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC

(2012) Marc R Fabian et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Crystal Structure of Human Argonaute2

(2012) N. T. Schirle et al.   SCIENCE

Modeling RNA interference in mammalian cells

(2011) Giulia Cuccato et al.   BMC Systems Biology

Analysis of miRNA regulation suggests an explanation for ‘unexpected’ increase in target protein levels

(2011) Sucheta A. Gokhale et al.   Molecular BioSystems

High-throughput microfluidic single-cell RT-qPCR

(2011) A. K. White et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Persister Cells

(2010) Kim Lewis   Annual Review of Microbiology

Development of a novel method to detect intrinsic mRNA in a living cell by using a molecular beacon-immobilized nanoneedle

(2010) Takanori Kihara et al.   BIOSENSORS & BIOELECTRONICS

A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations

(2010) Sreenath V. Sharma et al.   CELL

MicroRNA: Biogenesis, Function and Role in Cancer

(2010) Leigh-Ann MacFarlane et al.   CURRENT GENOMICS

mRNA turnover rate limits siRNA and microRNA efficacy

(2010) Erik Larsson et al.   Molecular Systems Biology

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

Numerical modelling of microRNA-mediated mRNA decay identifies novel mechanism of microRNA controlled mRNA downregulation

(2010) Jiri Vohradsky et al.   NUCLEIC ACIDS RESEARCH

RNAi-based therapeutics-current status, challenges and prospects

(2009) Katrin Tiemann et al.   EMBO Molecular Medicine

Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes

(2009) Yanli Wang et al.   NATURE

A three-dimensional view of the molecular machinery of RNA interference

(2009) Martin Jinek et al.   NATURE

Small silencing RNAs: an expanding universe

(2009) Megha Ghildiyal et al.   NATURE REVIEWS GENETICS

Noncovalent Peptide-Mediated Delivery of Chemically Modified Steric Block Oligonucleotides Promotes Splice Correction: Quantitative Analysis of Uptake and Biological Effect

(2009) Sandra D. Laufer et al.   OLIGONUCLEOTIDES

Peptide-Mediated Cellular Delivery of Oligonucleotide-Based Therapeutics In Vitro: Quantitative Evaluation of Overall Efficacy Employing Easy to Handle Reporter Systems

(2008) S. Laufer et al.   CURRENT PHARMACEUTICAL DESIGN

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

(2008) Yanli Wang et al.   NATURE

Structure of the guide-strand-containing argonaute silencing complex

(2008) Yanli Wang et al.   NATURE

Small non-coding RNAs in animal development

(2008) Giovanni Stefani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay

(2008) Ana Eulalio et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An Analysis of Human MicroRNA and Disease Associations

(2008) Ming Lu et al.   PLoS One

In vitro reconstitution of the human RISC-loading complex

(2008) I. J. MacRae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA