RORα switches transcriptional mode of ERRγ that results in transcriptional repression of CYP2E1 under ethanol-exposure

22-S-Hydroxycholesterol protects against ethanol-induced liver injury by blocking the auto/paracrine activation of MCP-1 mediated by LXRα

(2015) Tae-Young Na et al.   JOURNAL OF PATHOLOGY

RORα Decreases Oxidative Stress Through the Induction of SOD2 and GPx1 Expression and Thereby Protects Against Nonalcoholic Steatohepatitis in Mice

(2014) Yong-Hyun Han et al.   ANTIOXIDANTS & REDOX SIGNALING

Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARα

(2014) Yan Lu et al.   JOURNAL OF CLINICAL INVESTIGATION

Inverse agonist of estrogen-related receptor γ controls Salmonella typhimurium infection by modulating host iron homeostasis

(2014) Don-Kyu Kim et al.   NATURE MEDICINE

New advances in molecular mechanisms and emerging therapeutic targets in alcoholic liver diseases

(2014) Jessica A Williams et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Ethanol and liver: Recent insights into the mechanisms of ethanol-induced fatty liver

(2014) Jinyao Liu   WORLD JOURNAL OF GASTROENTEROLOGY

Estrogen receptor ligands ameliorate fatty liver through a nonclassical estrogen receptor/Liver X receptor pathway in mice

(2013) Song-iee Han et al.   HEPATOLOGY

Global burden of alcoholic liver diseases

(2013) Jürgen Rehm et al.   JOURNAL OF HEPATOLOGY

A Promising Hepatocyte-Like Cell Line, CCL-13, Exhibits Good Liver Function Both In Vitro and in an Acute Liver Failure Model

(2013) T. Yang et al.   TRANSPLANTATION PROCEEDINGS

N-methylthioureas as new agonists of retinoic acid receptor-related orphan receptor

(2012) Yohan Park et al.   ARCHIVES OF PHARMACAL RESEARCH

Transcriptome analysis identifies TNF superfamily receptors as potential therapeutic targets in alcoholic hepatitis

(2012) Silvia Affò et al.   GUT

Estrogen-related receptor γ controls hepatic CB1receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol

(2012) Don-Kyu Kim et al.   GUT

Orphan Nuclear Receptor Estrogen-Related Receptor γ (ERRγ) Is Key Regulator of Hepatic Gluconeogenesis

(2012) Don-Kyu Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NF-κB–inducing kinase (NIK) promotes hyperglycemia and glucose intolerance in obesity by augmenting glucagon action

(2012) Liang Sheng et al.   NATURE MEDICINE

Regulation of p53 Stability and Apoptosis by a ROR Agonist

(2012) Yongjun Wang et al.   PLoS One

Action of RORs and their ligands in (patho)physiology

(2012) Laura A. Solt et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway

(2011) Timothy R. Peterson et al.   CELL

Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets

(2011) Bin Gao et al.   GASTROENTEROLOGY

An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: Regulation of proinflammatory cytokines and hepatic steatosis in mice

(2011) Pranoti Mandrekar et al.   HEPATOLOGY

Retinoic acid receptor-related orphan receptor α-induced activation of adenosine monophosphate-activated protein kinase results in attenuation of hepatic steatosis

(2011) Eun-Jin Kim et al.   HEPATOLOGY

Estrogen-related Receptor γ (ERRγ) Is a Novel Transcriptional Regulator of Phosphatidic Acid Phosphatase, LIPIN1, and Inhibits Hepatic Insulin Signaling

(2011) Don-Kyu Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of SR3335 (ML-176): A Synthetic RORα Selective Inverse Agonist

(2010) Naresh Kumar et al.   ACS Chemical Biology

The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

(2009) S. A. Bustin et al.   CLINICAL CHEMISTRY

The Orphan Nuclear Receptor RORα Restrains Adipocyte Differentiation through a Reduction of C/EBPβ Activity and Perilipin Gene Expression

(2009) Nobumichi Ohoka et al.   MOLECULAR ENDOCRINOLOGY

Paracrine Activation of Hepatic CB1 Receptors by Stellate Cell-Derived Endocannabinoids Mediates Alcoholic Fatty Liver

(2008) Won-il Jeong et al.   Cell Metabolism

Transcriptional Control of Energy Homeostasis by the Estrogen-Related Receptors

(2008) Vincent Giguère   ENDOCRINE REVIEWS

The Orphan Nuclear Receptor, RORα, Regulates Gene Expression That Controls Lipid Metabolism

(2008) Patrick Lau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Absence of the SRC-2 Coactivator Results in a Glycogenopathy Resembling Von Gierke's Disease

(2008) A. R. Chopra et al.   SCIENCE