Osteocytes and WNT: the Mechanical Control of Bone Formation

Signaling Networks that Control the Lineage Commitment and Differentiation of Bone Cells

(2012) Carrie S. Soltanoff et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

NMR structure of the Wnt modulator protein Sclerostin

(2009) Stella E. Weidauer et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Wnt inhibitory factor (WIF)-1 inhibits osteoblastic differentiation in mouse embryonic mesenchymal cells

(2009) Sun Wook Cho et al.   BONE

The mouse fibula as a suitable bone for the study of functional adaptation to mechanical loading

(2009) Alaa Moustafa et al.   BONE

Osteocyte morphology in human tibiae of different bone pathologies with different bone mineral density — Is there a role for mechanosensing?

(2009) Ruud P. van Hove et al.   BONE

The −9247 T/C polymorphism in the SOST upstream regulatory region that potentially affects C/EBPα and FOXA1 binding is associated with osteoporosis

(2009) Qing-Yang Huang et al.   BONE

Wnt signaling inhibits cementoblast differentiation and promotes proliferation

(2009) Eiji Nemoto et al.   BONE

Identification of differentially expressed genes between osteoblasts and osteocytes

(2009) Frane Paic et al.   BONE

The relation of femoral osteon geometry to age, sex, height and weight

(2009) Hayley M. Britz et al.   BONE

Interaction between PGE2 and EGF receptor through MAPKs in mouse embryonic stem cell proliferation

(2009) S. P. Yun et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Rho GTPase activity modulates Wnt3a/β-catenin signaling

(2009) Jessica Rossol-Allison et al.   CELLULAR SIGNALLING

A rough surface implant neck with microthreads reduces the amount of marginal bone loss: a prospective clinical study

(2009) Emanuel A. Bratu et al.   CLINICAL ORAL IMPLANTS RESEARCH

Clinical outcomes of sinus floor augmentation for implant placement using autogenous bone or bone substitutes: a systematic review

(2009) Emeka Nkenke et al.   CLINICAL ORAL IMPLANTS RESEARCH

Wnt Signaling and the Evolution of Embryonic Posterior Development

(2009) Benjamin L. Martin et al.   CURRENT BIOLOGY

PHEX, FGF23, DMP1 and beyond

(2009) Tim M Strom et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Cross-talk among bone cells

(2009) Koichi Matsuo   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Apc inhibition of Wnt signaling regulates supernumerary tooth formation during embryogenesis and throughout adulthood

(2009) X.-P. Wang et al.   DEVELOPMENT

Wnt/beta-catenin signaling plays an essential role in activation of odontogenic mesenchyme during early tooth development

(2009) Jianquan Chen et al.   DEVELOPMENTAL BIOLOGY

Wnt signaling as a therapeutic target for bone diseases

(2009) Luke H Hoeppner et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Wnt signaling pathways meet Rho GTPases

(2009) K. Schlessinger et al.   GENES & DEVELOPMENT

Characterization of the Structural Features and Interactions of Sclerostin

(2009) Vaclav Veverka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Short Treatment With an Antibody to Sclerostin Can Inhibit Bone Loss in an Ongoing Model of Colitis*

(2009) Alison Eddleston et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Sclerostin Mediates Bone Response to Mechanical Unloading Through Antagonizing Wnt/β-Catenin Signaling

(2009) Chuwen Lin et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Axin2 controls bone remodeling through the  -catenin-BMP signaling pathway in adult mice

(2009) Y. Yan et al.   JOURNAL OF CELL SCIENCE

Mechanically induced osteogenic differentiation - the role of RhoA, ROCKII and cytoskeletal dynamics

(2009) E. J. Arnsdorf et al.   JOURNAL OF CELL SCIENCE

Runx2 and bone morphogenic protein 2 regulate the expression of an alternative Lef1 transcript during osteoblast maturation

(2009) Luke H. Hoeppner et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Wnt/β-catenin Inhibits Dental Pulp Stem Cell Differentiation

(2009) E.L. Scheller et al.   JOURNAL OF DENTAL RESEARCH

Sclerostin in Mineralized Matrices and van Buchem Disease

(2009) R.L. van Bezooijen et al.   JOURNAL OF DENTAL RESEARCH

Putative signaling action of amelogenin utilizes the Wnt/β-catenin pathway

(2009) M. Matsuzawa et al.   JOURNAL OF PERIODONTAL RESEARCH

The dynamic natures of implant loading

(2009) Rui-Feng Wang et al.   JOURNAL OF PROSTHETIC DENTISTRY

Is Wnt signalling the final common pathway leading to bone formation?

(2009) Frances Milat et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

β-Catenin hits chromatin: regulation of Wnt target gene activation

(2009) Christian Mosimann et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

An olive branch to two theories

(2009) Leonie Welberg   NATURE REVIEWS NEUROSCIENCE

Bone morphogenetic proteins for periodontal and alveolar indications; biological observations - clinical implications

(2009) UME Wikesjö et al.   Orthodontics & Craniofacial Research

Bili Inhibits Wnt/β-Catenin Signaling by Regulating the Recruitment of Axin to LRP6

(2009) Lorna S. Kategaya et al.   PLoS One

Mechanobiology of the Skeleton

(2009) C. H. Turner et al.   Science Signaling

Exercise and Bone Mass in Adults

(2009) Amelia Guadalupe-Grau et al.   SPORTS MEDICINE

Growth and the Modeling/Remodeling of the Alveolar Bone of the Rat Incisor

(2008) José Merzel et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Primary Cilia: Cellular Sensors for the Skeleton

(2008) Charles T. Anderson et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Osteoclast–osteoblast communication

(2008) Koichi Matsuo et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Bone remodelling: its local regulation and the emergence of bone fragility

(2008) T. John Martin et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Myeloma-derived Dickkopf-1 disrupts Wnt-regulated osteoprotegerin and RANKL production by osteoblasts: a potential mechanism underlying osteolytic bone lesions in multiple myeloma

(2008) Y.-W. Qiang et al.   BLOOD

Osteocyte morphology in fibula and calvaria — Is there a role for mechanosensing?

(2008) Aviral Vatsa et al.   BONE

Osteocytes, mechanosensing and Wnt signaling

(2008) Lynda F. Bonewald et al.   BONE

Do osteocytes contribute to bone mineral homeostasis? Osteocytic osteolysis revisited

(2008) Anna Teti et al.   BONE

The Binding Between Sclerostin and LRP5 is Altered by DKK1 and by High-Bone Mass LRP5 Mutations

(2008) Wendy Balemans et al.   CALCIFIED TISSUE INTERNATIONAL

Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis

(2008) Veronique Nogueira et al.   CANCER CELL

Wnt signaling and stem cell control

(2008) Roel Nusse   CELL RESEARCH

Wnt3a and Dkk1 Regulate Distinct Internalization Pathways of LRP6 to Tune the Activation of β-Catenin Signaling

(2008) Hideki Yamamoto et al.   DEVELOPMENTAL CELL

FHL2 mediates dexamethasone-induced mesenchymal cell differentiation into osteoblasts by activating Wnt/β-catenin signaling-dependent Runx2 expression

(2008) Zahia Hamidouche et al.   FASEB JOURNAL

Wdr5 Is Essential for Osteoblast Differentiation

(2008) Eric D. Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adaptation of Connexin 43-Hemichannel Prostaglandin Release to Mechanical Loading

(2008) Arlene J. Siller-Jackson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wnt Signal Amplification via Activity, Cooperativity, and Regulation of Multiple Intracellular PPPSP Motifs in the Wnt Co-receptor LRP6

(2008) Bryan T. MacDonald et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unique and Overlapping Functions of GSK-3 Isoforms in Cell Differentiation and Proliferation and Cardiovascular Development

(2008) Thomas Force et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Round versus flat: Bone cell morphology, elasticity, and mechanosensing

(2008) Rommel G. Bacabac et al.   JOURNAL OF BIOMECHANICS

Connexin 43 Is Required for the Anti-Apoptotic Effect of Bisphosphonates on Osteocytes and Osteoblasts In Vivo

(2008) Lilian I Plotkin et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone Strength

(2008) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Inhibiting Dickkopf-1 (Dkk1) Removes Suppression of Bone Formation and Prevents the Development of Osteolytic Bone Disease in Multiple Myeloma

(2008) Deborah J Heath et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength in a Rat Model of Postmenopausal Osteoporosis*

(2008) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Chibby cooperates with 14-3-3 to regulate β-catenin subcellular distribution and signaling activity

(2008) Feng-Qian Li et al.   JOURNAL OF CELL BIOLOGY

BMP-9-induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/β-catenin signalling

(2008) Ni Tang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Single minimally invasive surgical technique with an enamel matrix derivative to treat multiple adjacent intra-bony defects: clinical outcomes and patient morbidity

(2008) Pierpaolo Cortellini et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Ten-year results following treatment of intra-bony defects with enamel matrix proteins and guided tissue regeneration

(2008) Anton Sculean et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Clinical outcomes with bioactive agents alone or in combination with grafting or guided tissue regeneration

(2008) Leonardo Trombelli et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Regeneration of periodontal tissues: combinations of barrier membranes and grafting materials - biological foundation and preclinical evidence: A systematic review

(2008) Anton Sculean et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Remodeling of fracture callus in mice is consistent with mechanical loading and bone remodeling theory

(2008) Hanna Isaksson et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

N-Cadherin Interacts with Axin and LRP5 To Negatively Regulate Wnt/ -Catenin Signaling, Osteoblast Function, and Bone Formation

(2008) E. Hay et al.   MOLECULAR AND CELLULAR BIOLOGY

Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche

(2008) Cristina Lo Celso et al.   NATURE

Mechanotransduction in development: a growing role for contractility

(2008) Michele A. Wozniak et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

(2008) Ning Wang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Control of Bone Mass and Remodeling by PTH Receptor Signaling in Osteocytes

(2008) Charles A. O'Brien et al.   PLoS One

Inhibition of Wnt signaling by the osteoblast-specific transcription factor Osterix

(2008) C. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tensegrity-based mechanosensing from macro to micro

(2008) Donald E. Ingber   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Alternative Wnt Signaling Is Initiated by Distinct Receptors

(2008) R. van Amerongen et al.   Science Signaling

Differentiation of Osteoblasts and Osteocytes from Mesenchymal Stem Cells

(2008) Terhi Heino et al.   Current Stem Cell Research & Therapy

Targeting the Wnt signaling pathway to augment bone formation

(2008) Mohammad Shahnazari et al.   Current Osteoporosis Reports

Wnt/β-catenin signaling directs multiple stages of tooth morphogenesis

(2007) Fei Liu et al.   DEVELOPMENTAL BIOLOGY