Age Related Changes in Fractional Elimination Pathways for Drugs: Assessing the Impact of Variable Ontogeny on Metabolic Drug-Drug Interactions

Do Children Have the Same Vulnerability to Metabolic Drug-Drug Interactions as Adults? A Critical Analysis of the Literature

(2013) Farzaneh Salem et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Physiologically Based Pharmacokinetics Joined With In Vitro–In Vivo Extrapolation of ADME: A Marriage Under the Arch of Systems Pharmacology

(2012) A Rostami-Hodjegan   CLINICAL PHARMACOLOGY & THERAPEUTICS

Regulatory Experience With Physiologically Based Pharmacokinetic Modeling for Pediatric Drug Trials

(2012) R Leong et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Resurgence in the use of physiologically based pharmacokinetic models in pediatric clinical pharmacology: parallel shift in incorporating the knowledge of biological elements and increased applicability to drug development and clinical practice

(2010) Trevor N. Johnson et al.   PEDIATRIC ANESTHESIA

Human hepatic CYP2B6 developmental expression: The impact of age and genotype

(2009) Edward L. Croom et al.   BIOCHEMICAL PHARMACOLOGY

Population Pharmacokinetics of Sildenafil in Term Neonates: Evidence of Rapid Maturation of Metabolic Clearance in the Early Postnatal Period

(2008) A Mukherjee et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Human renal function maturation: a quantitative description using weight and postmenstrual age

(2008) Malin M. Rhodin et al.   PEDIATRIC NEPHROLOGY

Development of CYP2D6 and CYP3A4 in the First Year of Life

(2007) TN Johnson et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Both postnatal and postmenstrual age contribute to the interindividual variability in tramadol glucuronidation in neonates

(2007) K. Allegaert et al.   EARLY HUMAN DEVELOPMENT