TLR3 agonist and CD40-targeting vaccination induces immune responses and reduces HIV-1 reservoirs

Superiority in Rhesus Macaques of Targeting HIV-1 Env gp140 to CD40 versus LOX-1 in Combination with Replication-Competent NYVAC-KC for Induction of Env-Specific Antibody and T Cell Responses

(2017) Gerard Zurawski et al.   JOURNAL OF VIROLOGY

The TLR9 agonist MGN1703 triggers a potent type I interferon response in the sigmoid colon

(2017) A R Krarup et al.   Mucosal Immunology

Toll-like receptor 3 activation selectively reverses HIV latency in microglial cells

(2017) David Alvarez-Carbonell et al.   Retrovirology

Human innate responses and adjuvant activity of TLR ligands in vivo in mice reconstituted with a human immune system

(2017) Liang Cheng et al.   VACCINE

Humanized Mouse Models for Human Immunodeficiency Virus Infection

(2017) Matthew D. Marsden et al.   Annual Review of Virology

Blocking type I interferon signaling enhances T cell recovery and reduces HIV-1 reservoirs

(2016) Liang Cheng et al.   JOURNAL OF CLINICAL INVESTIGATION

Therapeutic vaccines and immunological intervention in HIV infection

(2016) Giuseppe Pantaleo et al.   Current Opinion in HIV and AIDS

The Effect of Latency Reversal Agents on Primary CD8 + T Cells: Implications for Shock and Kill Strategies for Human Immunodeficiency Virus Eradication

(2016) Victoria E. Walker-Sperling et al.   EBioMedicine

Functional Specialty of CD40 and Dendritic Cell Surface Lectins for Exogenous Antigen Presentation to CD8+ and CD4+ T Cells

(2016) Wenjie Yin et al.   EBioMedicine

Targeting HIV-1 Env gp140 to LOX-1 Elicits Immune Responses in Rhesus Macaques

(2016) Gerard Zurawski et al.   PLoS One

HIV therapeutic vaccines: moving towards a functional cure

(2015) Geetha H Mylvaganam et al.   CURRENT OPINION IN IMMUNOLOGY

In VitroReactivation of Replication-Competent and Infectious HIV-1 by Histone Deacetylase Inhibitors

(2015) Riddhima Banga et al.   JOURNAL OF VIROLOGY

B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers

(2015) Yoshinori Fukazawa et al.   NATURE MEDICINE

Delivering HIV Gagp24 to DCIR Induces Strong Antibody Responses In Vivo

(2015) Anne-Laure Flamar et al.   PLoS One

Broadly Neutralizing Antibodies and Viral Inducers Decrease Rebound from HIV-1 Latent Reservoirs in Humanized Mice

(2014) Ariel Halper-Stromberg et al.   CELL

Dendritic cell-based therapeutic vaccine elicits polyfunctional HIV-specific T-cell immunity associated with control of viral load

(2014) Yves Lévy et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Eradicating HIV-1 infection: seeking to clear a persistent pathogen

(2014) Nancie M. Archin et al.   NATURE REVIEWS MICROBIOLOGY

Immunologic strategies for HIV-1 remission and eradication

(2014) D. H. Barouch et al.   SCIENCE

Dendritic Cell-Targeted Vaccines

(2014) Lillian Cohn et al.   Frontiers in Immunology

Targeting concatenated HIV antigens to human CD40 expands a broad repertoire of multifunctional CD4+ and CD8+ T cells

(2013) Anne-Laure Flamar et al.   AIDS

Dendritic-Cell-Based Therapeutic Cancer Vaccines

(2013) Karolina Palucka et al.   IMMUNITY

Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3+dendritic cells at cross presentation

(2013) Lillian Cohn et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Barriers to a cure for HIV: new ways to target and eradicate HIV-1 reservoirs

(2013) Christine Katlama et al.   LANCET

Reactivation of latent HIV-1 in central memory CD4+ T cells through TLR-1/2 stimulation

(2013) Camille L Novis et al.   Retrovirology

The histone deacetylase inhibitor, romidepsin, suppresses cellular immune functions of cutaneous T-cell lymphoma patients

(2012) Michael J. Kelly-Sell et al.   AMERICAN JOURNAL OF HEMATOLOGY

Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cells

(2012) B. Chatterjee et al.   BLOOD

HIV-1 immunopathogenesis in humanized mouse models

(2012) Liguo Zhang et al.   Cellular & Molecular Immunology

Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production

(2012) Matthieu Perreau et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

(2012) N. M. Archin et al.   NATURE

Shock and kill

(2012) Steven G. Deeks   NATURE

Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates

(2011) B. J. Flynn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV Infection, Inflammation, Immunosenescence, and Aging

(2010) Steven G. Deeks   Annual Review of Medicine

Vaccine Adjuvants: Putting Innate Immunity to Work

(2010) Robert L. Coffman et al.   IMMUNITY

The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8α+dendritic cells

(2010) Karine Crozat et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human CD141+(BDCA-3)+dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens

(2010) Sarah L. Jongbloed et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+cells as homologues of mouse CD8+dendritic cells

(2010) Annabell Bachem et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Characterization of human DNGR-1+BDCA3+leukocytes as putative equivalents of mouse CD8α+dendritic cells

(2010) Lionel Franz Poulin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Selective Transduction of Dendritic Cells in Human Lymph Nodes and Superior Induction of High-avidity Melanoma-reactive Cytotoxic T Cells by a CD40-targeted Adenovirus

(2010) Basav N. Hangalapura et al.   JOURNAL OF IMMUNOTHERAPY