Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis

Central GLP-2 Enhances Hepatic Insulin Sensitivity via Activating PI3K Signaling in POMC Neurons

(2013) Xuemei Shi et al.   Cell Metabolism

Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice

(2012) Eric D. Berglund et al.   JOURNAL OF CLINICAL INVESTIGATION

Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover

(2012) Roger H. Unger et al.   JOURNAL OF CLINICAL INVESTIGATION

What is the prognosis for new centrally-acting anti-obesity drugs?

(2012) David J. Heal et al.   NEUROPHARMACOLOGY

The FDA's Assessment of Two Drugs for Chronic Weight Management

(2012) Eric Colman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Activation of the central melanocortin system contributes to the increased arterial pressure in obese Zucker rats

(2011) Jussara M. do Carmo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Serotonergic Anti-Obesity Agents

(2011) Jason C.G. Halford et al.   DRUGS

Role of central serotonin and melanocortin systems in the control of energy balance

(2011) Oliver J. Marston et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Serotonin 2C Receptor Activates a Distinct Population of Arcuate Pro-opiomelanocortin Neurons via TRPC Channels

(2011) Jong-Woo Sohn et al.   NEURON

The use of serotonergic drugs to treat obesity – is there any hope?

(2011) Nicholas Bello et al.   Drug Design Development and Therapy

Direct Insulin and Leptin Action on Pro-opiomelanocortin Neurons Is Required for Normal Glucose Homeostasis and Fertility

(2010) Jennifer W. Hill et al.   Cell Metabolism

Segregation of Acute Leptin and Insulin Effects in Distinct Populations of Arcuate Proopiomelanocortin Neurons

(2010) K. W. Williams et al.   JOURNAL OF NEUROSCIENCE

A Serotonin and Melanocortin Circuit Mediates D-Fenfluramine Anorexia

(2010) Y. Xu et al.   JOURNAL OF NEUROSCIENCE

Pomc-expressing progenitors give rise to antagonistic neuronal populations in hypothalamic feeding circuits

(2010) Stephanie L Padilla et al.   NATURE MEDICINE

5-HT2CRs expressed by pro-opiomelanocortin neurons regulate insulin sensitivity in liver

(2010) Yong Xu et al.   NATURE NEUROSCIENCE

Effect of Sibutramine on Cardiovascular Outcomes in Overweight and Obese Subjects

(2010) W. Philip T. James et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dysregulated Editing of Serotonin 2C Receptor mRNAs Results in Energy Dissipation and Loss of Fat Mass

(2008) Y. Kawahara et al.   JOURNAL OF NEUROSCIENCE

Pharmacological targeting of the serotonergic system for the treatment of obesity

(2008) Alastair S. Garfield et al.   JOURNAL OF PHYSIOLOGY-LONDON

5-HT2CRs Expressed by Pro-Opiomelanocortin Neurons Regulate Energy Homeostasis

(2008) Yong Xu et al.   NEURON

Serotonin 5-HT2CReceptor Agonist Promotes Hypophagia via Downstream Activation of Melanocortin 4 Receptors

(2007) Daniel D. Lam et al.   ENDOCRINOLOGY

Synergistic Impairment of Glucose Homeostasis inob/obMice Lacking Functional Serotonin 2C Receptors

(2007) Jennifer M. Wade et al.   ENDOCRINOLOGY