IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality

Stimulation of Rho signaling by pathologic mechanical stretch is a “second hit” to Rho-independent lung injury induced by IL-6

(2012) Anna A. Birukova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Hitting a complex target: an update on interleukin-6 trans-signalling

(2012) Georg H Waetzig et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Deletion of IκBα Activates RelA to Reduce Acute Pancreatitis in Mice Through Up-regulation of Spi2A

(2012) Patrick Neuhöfer et al.   GASTROENTEROLOGY

Toxin-induced RhoA Activity Mediates CCL1-triggered Signal Transducers and Activators of Transcription Protein Signaling

(2012) Simone Reipschläger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatocyte-specific mutation of both NF-κB RelA and STAT3 abrogates the acute phase response in mice

(2012) Lee J. Quinton et al.   JOURNAL OF CLINICAL INVESTIGATION

CXCR2 in Acute Lung Injury

(2012) F. M. Konrad et al.   MEDIATORS OF INFLAMMATION

Multi-tasking: nuclear transcription factors with novel roles in the mitochondria

(2012) Karol Szczepanek et al.   TRENDS IN CELL BIOLOGY

The Acute Respiratory Distress Syndrome: Pathogenesis and Treatment

(2011) Michael A. Matthay et al.   Annual Review of Pathology-Mechanisms of Disease

The pro- and anti-inflammatory properties of the cytokine interleukin-6

(2011) Jürgen Scheller et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer

(2011) Marina Lesina et al.   CANCER CELL

Selective blockade of interleukin-6 trans-signaling improves survival in a murine polymicrobial sepsis model*

(2011) Tanja Barkhausen et al.   CRITICAL CARE MEDICINE

Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling

(2011) Simon A. Jones et al.   JOURNAL OF CLINICAL INVESTIGATION

Cytokines and Organ Failure in Acute Pancreatitis

(2011) Marie Louise Malmstrøm et al.   PANCREAS

Prediction of outcome in patients with acute respiratory distress syndrome by bronchoalveolar lavage inflammatory mediators

(2010) Wei-Chieh Lin et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function

(2010) Leif E. Sander et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Current management and novel insights in acute pancreatitis

(2009) Venkata Muddana et al.   Expert Review of Gastroenterology & Hepatology

ALTERED PULMONARY INTERLEUKIN-6 SIGNALING IN PRETERM INFANTS DEVELOPING BRONCHOPULMONARY DYSPLASIA

(2008) Philipp von Bismarck et al.   EXPERIMENTAL LUNG RESEARCH

IL-6 transsignalling modulates the early effector phase of EAE and targets the blood-brain barrier

(2008) Ralf A. Linker et al.   JOURNAL OF NEUROIMMUNOLOGY

Monocyte Chemoattractant Protein 1, Active Carboxypeptidase B and CAPAP at Hospital Admission Are Predictive Markers for Severe Acute Pancreatitis

(2008) S. Régner et al.   PANCREATOLOGY

Prediction of severe acute pancreatitis: Current knowledge and novel insights

(2008) Georgios I Papachristou   WORLD JOURNAL OF GASTROENTEROLOGY