Complement factor H–related hybrid protein deregulates complement in dense deposit disease

C3 glomerulopathy–associated CFHR1 mutation alters FHR oligomerization and complement regulation

(2013) Agustín Tortajada et al.   JOURNAL OF CLINICAL INVESTIGATION

Incidence of End-Stage Renal Disease in the Turkish-Cypriot Population of Northern Cyprus: A Population Based Study

(2013) Thomas M. F. Connor et al.   PLoS One

Human Factor H-Related Protein 2 (CFHR2) Regulates Complement Activation

(2013) Hannes U. Eberhardt et al.   PLoS One

Causes of Alternative Pathway Dysregulation in Dense Deposit Disease

(2012) Y. Zhang et al.   Clinical Journal of the American Society of Nephrology

Eculizumab for Dense Deposit Disease and C3 Glomerulonephritis

(2012) A. S. Bomback et al.   Clinical Journal of the American Society of Nephrology

A Hybrid CFHR3-1 Gene Causes Familial C3 Glomerulopathy

(2012) T. H. Malik et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Acquired and genetic complement abnormalities play a critical role in dense deposit disease and other C3 glomerulopathies

(2012) Aude Servais et al.   KIDNEY INTERNATIONAL

C3 glomerulonephritis and CFHR5 nephropathy

(2012) D. P. Gale et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Eculizumab for the Treatment of Dense-Deposit Disease

(2012) Marina Vivarelli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Eculizumab in a Patient with Dense-Deposit Disease

(2012) Erica Daina et al.   NEW ENGLAND JOURNAL OF MEDICINE

Molecular Interaction Studies Using Microscale Thermophoresis

(2011) Moran Jerabek-Willemsen et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Familial C3 Glomerulopathy Associated with CFHR5 Mutations: Clinical Characteristics of 91 Patients in 16 Pedigrees

(2011) Y. Athanasiou et al.   Clinical Journal of the American Society of Nephrology

Immune Evasion of Moraxella catarrhalis Involves Ubiquitous Surface Protein A-Dependent C3d Binding

(2011) T. Hallstrom et al.   JOURNAL OF IMMUNOLOGY

Membranoproliferative glomerulonephritis and C3 glomerulopathy: resolving the confusion

(2011) Sanjeev Sethi et al.   KIDNEY INTERNATIONAL

Achievements and Limitations of Complement Inhibition by Eculizumab in Paroxysmal Nocturnal Hemoglobinuria: The Role of Complement Component 3

(2011) A. M. Risitano et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Combined C3b and Factor B Autoantibodies and MPGN Type II

(2011) Qian Chen et al.   NEW ENGLAND JOURNAL OF MEDICINE

An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD)

(2010) Lars G. Fritsche et al.   HUMAN MOLECULAR GENETICS

Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation

(2010) Rubén Martínez-Barricarte et al.   JOURNAL OF CLINICAL INVESTIGATION

Identification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritis

(2010) Daniel P Gale et al.   LANCET

Complement Factor H-Related Proteins CFHR2 and CFHR5 Represent Novel Ligands for the Infection-Associated CRASP Proteins of Borrelia burgdorferi

(2010) Corinna Siegel et al.   PLoS One

Structures of C3b in Complex with Factors B and D Give Insight into Complement Convertase Formation

(2010) F. Forneris et al.   SCIENCE

Protein-binding assays in biological liquids using microscale thermophoresis

(2010) Christoph J. Wienken et al.   Nature Communications

Factor H-related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation

(2009) S. Heinen et al.   BLOOD

Membranoproliferative glomerulonephritis

(2009) Bassam Alchi et al.   PEDIATRIC NEPHROLOGY

C3 deposition glomerulopathy due to a functional Factor H defect

(2008) Sandra Habbig et al.   KIDNEY INTERNATIONAL

Complement factor H related proteins in immune diseases

(2008) Christine Skerka et al.   VACCINE

The complement fitness Factor H: Role in human diseases and for immune escape of pathogens, like pneumococci

(2008) Peter F. Zipfel et al.   VACCINE