Insulin receptor substrate signaling suppresses neonatal autophagy in the heart

Mechanistic Target of Rapamycin (Mtor) Is Essential for Murine Embryonic Heart Development and Growth

(2013) Yi Zhu et al.   PLoS One

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival

(2012) Alejo Efeyan et al.   NATURE

Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy

(2011) Rodrigo Troncoso et al.   CARDIOVASCULAR RESEARCH

Cardiac anaplerosis in health and disease: food for thought

(2011) C. Des Rosiers et al.   CARDIOVASCULAR RESEARCH

PGC-1β Deficiency Accelerates the Transition to Heart Failure in Pressure Overload Hypertrophy

(2011) Christian Riehle et al.   CIRCULATION RESEARCH

IRS2 increases mitochondrial dysfunction and oxidative stress in a mouse model of Huntington disease

(2011) Marianna Sadagurski et al.   JOURNAL OF CLINICAL INVESTIGATION

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Branched-Chain Amino Acid Supplementation Promotes Survival and Supports Cardiac and Skeletal Muscle Mitochondrial Biogenesis in Middle-Aged Mice

(2010) Giuseppe D'Antona et al.   Cell Metabolism

MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice

(2010) Denghong Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Proteomic remodelling of mitochondrial oxidative pathways in pressure overload-induced heart failure

(2009) Heiko Bugger et al.   CARDIOVASCULAR RESEARCH

Contribution of Impaired Myocardial Insulin Signaling to Mitochondrial Dysfunction and Oxidative Stress in the Heart

(2009) Sihem Boudina et al.   CIRCULATION

Tissue-Specific Remodeling of the Mitochondrial Proteome in Type 1 Diabetic Akita Mice

(2009) H. Bugger et al.   DIABETES

Interaction of myocardial insulin receptor and IGF receptor signaling in exercise-induced cardiac hypertrophy

(2009) Hiroyuki Ikeda et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Inactivation of Hepatic Foxo1 by Insulin Signaling Is Required for Adaptive Nutrient Homeostasis and Endocrine Growth Regulation

(2008) Xiaocheng C. Dong et al.   Cell Metabolism

Recycle or die: The role of autophagy in cardioprotection

(2008) Åsa B. Gustafsson et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Insulin-Like Growth Factor I Receptor Signaling Is Required for Exercise-Induced Cardiac Hypertrophy

(2008) Jaetaek Kim et al.   MOLECULAR ENDOCRINOLOGY

Regulation of TORC1 by Rag GTPases in nutrient response

(2008) Eunjung Kim et al.   NATURE CELL BIOLOGY

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

(2008) Y. Sancak et al.   SCIENCE