Autoimmunity risk alleles: hotspots in B cell regulatory signaling pathways

A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models

(2013) Xuezhi Dai et al.   JOURNAL OF CLINICAL INVESTIGATION

Interaction of TAPP adapter proteins with phosphatidylinositol (3,4)-bisphosphate regulates B-cell activation and autoantibody production

(2012) Ivan Landego et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Transcriptional effects of a lupus-associated polymorphism in the 5′ untranslated region (UTR) of human complement receptor 2 (CR2/CD21)

(2012) Mark N. Cruickshank et al.   MOLECULAR IMMUNOLOGY

CSK regulatory polymorphism is associated with systemic lupus erythematosus and influences B-cell signaling and activation

(2012) Nataly Manjarrez-Orduño et al.   NATURE GENETICS

Endogenous viruses: insights into viral evolution and impact on host biology

(2012) Cédric Feschotte et al.   NATURE REVIEWS GENETICS

Central B-Cell Tolerance: Where Selection Begins

(2012) R. Pelanda et al.   Cold Spring Harbor Perspectives in Biology

Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genesBANK1andBLK

(2011) Casimiro Castillejo-López et al.   ANNALS OF THE RHEUMATIC DISEASES

Monophosphorylation of CD79a and CD79b ITAM Motifs Initiates a SHIP-1 Phosphatase-Mediated Inhibitory Signaling Cascade Required for B Cell Anergy

(2011) Shannon K. O'Neill et al.   IMMUNITY

The autoimmune disease–associated PTPN22 variant promotes calpain-mediated Lyp/Pep degradation associated with lymphocyte and dendritic cell hyperresponsiveness

(2011) Jinyi Zhang et al.   NATURE GENETICS

Risk Alleles for Systemic Lupus Erythematosus in a Large Case-Control Collection and Associations with Clinical Subphenotypes

(2011) Kimberly E. Taylor et al.   PLoS Genetics

Suppression of Phosphatidylinositol 3,4,5-Trisphosphate Production Is a Key Determinant of B Cell Anergy

(2009) Cecille D. Browne et al.   IMMUNITY

Protein Tyrosine Phosphatases in Autoimmunity

(2008) Torkel Vang et al.   Annual Review of Immunology