A high-throughput single-cell analysis of human CD8+ T cell functions reveals discordance for cytokine secretion and cytolysis

High-Programmed Death-1 Levels on Hepatitis C Virus-Specific T Cells during Acute Infection Are Associated with Viral Persistence and Require Preservation of Cognate Antigen during Chronic Infection

(2014) A. Rutebemberwa et al.   JOURNAL OF IMMUNOLOGY

Development and optimization of a process for automated recovery of single cells identified by microengraving

(2010) Jae Hyeok Choi et al.   BIOTECHNOLOGY PROGRESS

Living in a house of cards: re-evaluating CD8+ T-cell immune correlates against HIV

(2010) George Makedonas et al.   IMMUNOLOGICAL REVIEWS

Enhanced Anti-HIV Functional Activity Associated with Gag-Specific CD8 T-Cell Responses

(2010) B. Julg et al.   JOURNAL OF VIROLOGY

Multidimensional analysis of the frequencies and rates of cytokine secretion from single cells by quantitative microengraving

(2010) Qing Han et al.   LAB ON A CHIP

Dynamic regulation of functionally distinct virus-specific T cells

(2010) Zaza M. Ndhlovu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation

(2010)   SCIENCE

Perforin Expression Directly Ex Vivo by HIV-Specific CD8+ T-Cells Is a Correlate of HIV Elite Control

(2010) Adam R. Hersperger et al.   PLoS Pathogens

Potent HIV-specific responses are enriched in a unique subset of CD8+ T cells that coexpresses CD4 on its surface

(2009) A. Zloza et al.   BLOOD

Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity

(2009) J. R. Almeida et al.   BLOOD

Distinct Profiles of Cytotoxic Granules in Memory CD8 T Cells Correlate with Function, Differentiation Stage, and Antigen Exposure

(2009) A. Harari et al.   JOURNAL OF VIROLOGY

Differential Neutralization of Human Immunodeficiency Virus (HIV) Replication in Autologous CD4 T Cells by HIV-Specific Cytotoxic T Lymphocytes

(2009) H. Chen et al.   JOURNAL OF VIROLOGY

Screening individual hybridomas by microengraving to discover monoclonal antibodies

(2009) Adebola O Ogunniyi et al.   Nature Protocols

The role of IFN-γ Elispot assay in HIV vaccine research

(2009) Hendrik Streeck et al.   Nature Protocols

Concurrent detection of secreted products from human lymphocytes by microengraving: Cytokines and antigen-reactive antibodies

(2008) Elizabeth M. Bradshaw et al.   CLINICAL IMMUNOLOGY

Lytic Granule Loading of CD8+ T Cells Is Required for HIV-Infected Cell Elimination Associated with Immune Control

(2008) Stephen A. Migueles et al.   IMMUNITY

Measuring HIV‐1–Specific T Cell Immunity: How Valid Are Current Assays?

(2008) M. Patricia D’Souza et al.   JOURNAL OF INFECTIOUS DISEASES

Transmission and Long-Term Stability of Compensated CD8 Escape Mutations

(2008) A. Schneidewind et al.   JOURNAL OF VIROLOGY

CD8+ T cell efficacy in vaccination and disease

(2008) Victor Appay et al.   NATURE MEDICINE

Antigen Load and Viral Sequence Diversification Determine the Functional Profile of HIV-1–Specific CD8+ T Cells

(2008) Hendrik Streeck et al.   PLOS MEDICINE