Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells

A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with α1-antitrypsin deficiency

(2010) Elena Miranda et al.   HEPATOLOGY

Conformational Pathology of the Serpins: Themes, Variations, and Therapeutic Strategies

(2009) Bibek Gooptu et al.   Annual Review of Biochemistry

Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease

(2009) Krishanu Saha et al.   Cell Stem Cell

Induced Pluripotent Stem Cells and Embryonic Stem Cells Are Distinguished by Gene Expression Signatures

(2009) Mark H. Chin et al.   Cell Stem Cell

Single nucleotide polymorphism-mediated translational suppression of endoplasmic reticulum mannosidase I modifies the onset of end-stage liver disease in alpha1-antitrypsin deficiency

(2009) Shujuan Pan et al.   HEPATOLOGY

Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development

(2009) Thomas Touboul et al.   HEPATOLOGY

Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs

(2009) Gabsang Lee et al.   NATURE

Generation of pluripotent stem cells from patients with type 1 diabetes

(2009) R. Maehr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signaling Pathways Controlling Pluripotency and Early Cell Fate Decisions of Human Induced Pluripotent Stem Cells

(2009) Ludovic Vallier et al.   STEM CELLS

Disease-Specific Induced Pluripotent Stem Cells

(2008) In-Hyun Park et al.   CELL

Autophagic disposal of the aggregation-prone protein that causes liver inflammation and carcinogenesis in α-1-antitrypsin deficiency

(2008) D H Perlmutter   CELL DEATH AND DIFFERENTIATION

Evolving concepts in liver tissue modeling and implications forin vitrotoxicology

(2008) André Guillouzo et al.   Expert Opinion on Drug Metabolism & Toxicology

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE

Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons

(2008) J. T. Dimos et al.   SCIENCE