Building a Terminal

Transferable neuronal mini-cultures to accelerate screening in primary and induced pluripotent stem cell-derived neurons

(2015) Mark Niedringhaus et al.   Scientific Reports

Local F-actin Network Links Synapse Formation and Axon Branching

(2014) Poh Hui Chia et al.   CELL

The Relationship between PSD-95 Clustering and Spine Stability In Vivo

(2014) M. Cane et al.   JOURNAL OF NEUROSCIENCE

Bidirectional cargo transport: moving beyond tug of war

(2014) William O. Hancock   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dynamic mechanisms of neuroligin-dependent presynaptic terminal assembly in living cortical neurons

(2014) Luke AD Bury et al.   Neural Development

Presynaptic and Postsynaptic Scaffolds

(2014) Noam E. Ziv et al.   NEUROSCIENTIST

High Content Image Analysis Identifies Novel Regulators of Synaptogenesis in a High-Throughput RNAi Screen of Primary Neurons

(2014) Thomas J. F. Nieland et al.   PLoS One

Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins

(2014) B. G. Wilhelm et al.   SCIENCE

The Vesicle Protein SAM-4 Regulates the Processivity of Synaptic Vesicle Transport

(2014) Qun Zheng et al.   PLoS Genetics

Liprin-α2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission

(2013) Samantha A. Spangler et al.   JOURNAL OF CELL BIOLOGY

Liprin-α/SYD-2 determines the size of dense projections in presynaptic active zones inC. elegans

(2013) Maike Kittelmann et al.   JOURNAL OF CELL BIOLOGY

Trans-induced cis interaction in the tripartite NGL-1, netrin-G1 and LAR adhesion complex promotes development of excitatory synapses

(2013) Y. S. Song et al.   JOURNAL OF CELL SCIENCE

Membrane-Tethered Monomeric Neurexin LNS-Domain Triggers Synapse Formation

(2013) O. Gokce et al.   JOURNAL OF NEUROSCIENCE

Specific Trans-Synaptic Interaction with Inhibitory Interneuronal Neurexin Underlies Differential Ability of Neuroligins to Induce Functional Inhibitory Synapses

(2013) K. Futai et al.   JOURNAL OF NEUROSCIENCE

Netrin-1 Promotes Excitatory Synaptogenesis between Cortical Neurons by Initiating Synapse Assembly

(2013) J. S. Goldman et al.   JOURNAL OF NEUROSCIENCE

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

mSYD1A, a Mammalian Synapse-Defective-1 Protein, Regulates Synaptogenic Signaling and Vesicle Docking

(2013) Corinna Wentzel et al.   NEURON

The Balance between Capture and Dissociation of Presynaptic Proteins Controls the Spatial Distribution of Synapses

(2013) Ye E. Wu et al.   NEURON

Recombinant Probes for Visualizing Endogenous Synaptic Proteins in Living Neurons

(2013) Garrett G. Gross et al.   NEURON

Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex

(2013) T. Kadoshima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In VivoNeuron-Wide Analysis of Synaptic Vesicle Precursor Trafficking

(2013) Celine I. Maeder et al.   TRAFFIC

LAR-RPTPs: synaptic adhesion molecules that shape synapse development

(2013) Ji Won Um et al.   TRENDS IN CELL BIOLOGY

High-Throughput Genetic Screen for Synaptogenic Factors: Identification of LRP6 as Critical for Excitatory Synapse Development

(2013) Kamal Sharma et al.   Cell Reports

Late Recruitment of Synapsin to Nascent Synapses Is Regulated by Cdk5

(2013) Courtney Easley-Neal et al.   Cell Reports

Dynamics of presynaptic protein recruitment induced by local presentation of artificial adhesive contacts

(2012) Fernando Suarez et al.   Developmental Neurobiology

Netrin instructs synaptic vesicle clustering through Rac GTPase, MIG-10, and the actin cytoskeleton

(2012) Andrea K.H. Stavoe et al.   JOURNAL OF CELL BIOLOGY

Interleukin-1 Receptor Accessory Protein Organizes Neuronal Synaptogenesis as a Cell Adhesion Molecule

(2012) T. Yoshida et al.   JOURNAL OF NEUROSCIENCE

Formation of Golgi-Derived Active Zone Precursor Vesicles

(2012) C. Maas et al.   JOURNAL OF NEUROSCIENCE

Release probability of hippocampal glutamatergic terminals scales with the size of the active zone

(2012) Noemi Holderith et al.   NATURE NEUROSCIENCE

NAB-1 instructs synapse assembly by linking adhesion molecules and F-actin to active zone proteins

(2012) Poh Hui Chia et al.   NATURE NEUROSCIENCE

Neuroligin-1–dependent competition regulates cortical synaptogenesis and synapse number

(2012) Hyung-Bae Kwon et al.   NATURE NEUROSCIENCE

Cooperation of Syd-1 with Neurexin synchronizes pre- with postsynaptic assembly

(2012) David Owald et al.   NATURE NEUROSCIENCE

Facilitation of neocortical presynaptic terminal development by NMDA receptor activation

(2012) Michael P Sceniak et al.   Neural Development

Motor Protein KIF1A Is Essential for Hippocampal Synaptogenesis and Learning Enhancement in an Enriched Environment

(2012) Makoto Kondo et al.   NEURON

The Presynaptic Active Zone

(2012) Thomas C. Südhof   NEURON

Developmental Up-Regulation of Vesicular Glutamate Transporter-1 Promotes Neocortical Presynaptic Terminal Development

(2012) Corbett T. Berry et al.   PLoS One

Dimerization of postsynaptic neuroligin drives synaptic assembly via transsynaptic clustering of neurexin

(2012) S. L. Shipman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synapse development in health and disease

(2011) Jan Elizabeth Melom et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The X-linked intellectual disability protein IL1RAPL1 regulates excitatory synapse formation by binding PTPδ and RhoGAP2

(2011) Pamela Valnegri et al.   HUMAN MOLECULAR GENETICS

 -Pix Modulates Actin-Mediated Recruitment of Synaptic Vesicles to Synapses

(2011) Y. Sun et al.   JOURNAL OF NEUROSCIENCE

IL-1 Receptor Accessory Protein-Like 1 Associated with Mental Retardation and Autism Mediates Synapse Formation by Trans-Synaptic Interaction with Protein Tyrosine Phosphatase  

(2011) T. Yoshida et al.   JOURNAL OF NEUROSCIENCE

Piccolo Regulates the Dynamic Assembly of Presynaptic F-Actin

(2011) C. L. Waites et al.   JOURNAL OF NEUROSCIENCE

Liprin-Mediated Large Signaling Complex Organization Revealed by the Liprin-α/CASK and Liprin-α/Liprin-β Complex Structures

(2011) Zhiyi Wei et al.   MOLECULAR CELL

Coordinated trafficking of synaptic vesicle and active zone proteins prior to synapse formation

(2011) Luke AD Bury et al.   Neural Development

Hts/Adducin Controls Synaptic Elaboration and Elimination

(2011) Jan Pielage et al.   NEURON

Postsynaptic TrkC and Presynaptic PTPσ Function as a Bidirectional Excitatory Synaptic Organizing Complex

(2011) Hideto Takahashi et al.   NEURON

Investigating synapse formation and function using human pluripotent stem cell-derived neurons

(2011) J.-E. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Latrophilin 1 and its endogenous ligand Lasso/teneurin-2 form a high-affinity transsynaptic receptor pair with signaling capabilities

(2011) J.-P. Silva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptic Vesicle Exocytosis

(2011) T. C. Sudhof et al.   Cold Spring Harbor Perspectives in Biology

Trans-Synaptic Interaction of GluRδ2 and Neurexin through Cbln1 Mediates Synapse Formation in the Cerebellum

(2010) Takeshi Uemura et al.   CELL

Hooks and comets: The story of microtubule polarity orientation in the neuron

(2010) Peter W. Baas et al.   Developmental Neurobiology

N-cadherin and Neuroligins Cooperate to Regulate Synapse Formation in Hippocampal Cultures

(2010) Mytyl Aiga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alternative Splicing of Neuroligin Regulates the Rate of Presynaptic Differentiation

(2010) H. Lee et al.   JOURNAL OF NEUROSCIENCE

Synapse loss in dementias

(2010) Ryan Clare et al.   JOURNAL OF NEUROSCIENCE RESEARCH

An Arf-like Small G Protein, ARL-8, Promotes the Axonal Transport of Presynaptic Cargoes by Suppressing Vesicle Aggregation

(2010) Matthew P. Klassen et al.   NEURON

SynCAM 1 Adhesion Dynamically Regulates Synapse Number and Impacts Plasticity and Learning

(2010) Elissa M. Robbins et al.   NEURON

Essential cooperation of N-cadherin and neuroligin-1 in the transsynaptic control of vesicle accumulation

(2010) A. Stan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid structural alterations of the active zone lead to sustained changes in neurotransmitter release

(2010) J. Matz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The synapsins: Key actors of synapse function and plasticity

(2010) F. Cesca et al.   PROGRESS IN NEUROBIOLOGY

Early synaptic pathophysiology in neurodegeneration: insights from Huntington's disease

(2010) Austen J. Milnerwood et al.   TRENDS IN NEUROSCIENCES

Synapse formation regulated by protein tyrosine phosphatase receptor T through interaction with cell adhesion molecules and Fyn

(2009) So-Hee Lim et al.   EMBO JOURNAL

Dynein light chain regulates axonal trafficking and synaptic levels of Bassoon

(2009) Anna Fejtova et al.   JOURNAL OF CELL BIOLOGY

Rapid Assembly of Functional Presynaptic Boutons Triggered by Adhesive Contacts

(2009) A. L. Lucido et al.   JOURNAL OF NEUROSCIENCE

Presynaptic and Postsynaptic Interaction of the Amyloid Precursor Protein Promotes Peripheral and Central Synaptogenesis

(2009) Z. Wang et al.   JOURNAL OF NEUROSCIENCE

The NGL family of leucine-rich repeat-containing synaptic adhesion molecules

(2009) Jooyeon Woo et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Long-term, high-resolution imaging in the mouse neocortex through a chronic cranial window

(2009) Anthony Holtmaat et al.   Nature Protocols

Traffic control: regulation of kinesin motors

(2009) Kristen J. Verhey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

An Unbiased Expression Screen for Synaptogenic Proteins Identifies the LRRTM Protein Family as Synaptic Organizers

(2009) Michael W. Linhoff et al.   NEURON

LRRTM2 Interacts with Neurexin1 and Regulates Excitatory Synapse Formation

(2009) Joris de Wit et al.   NEURON

LRRTM2 Functions as a Neurexin Ligand in Promoting Excitatory Synapse Formation

(2009) Jaewon Ko et al.   NEURON

Rapid Axonal Sprouting and Pruning Accompany Functional Reorganization in Primary Visual Cortex

(2009) Homare Yamahachi et al.   NEURON

Synaptic scaffolding protein SYD-2 clusters and activates kinesin-3 UNC-104 in C. elegans

(2009) O. I. Wagner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Actin and Microtubule-Based Cytoskeletal Cues Direct Polarized Targeting of Proteins in Neurons

(2009) D. B. Arnold   Science Signaling

CASK Functions as a Mg2+-Independent Neurexin Kinase

(2008) Konark Mukherjee et al.   CELL

Expression and adhesion profiles of SynCAM molecules indicate distinct neuronal functions

(2008) Lisa A. Thomas et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Nervous Wreck and Cdc42 Cooperate to Regulate Endocytic Actin Assembly during Synaptic Growth

(2008) A. A. Rodal et al.   JOURNAL OF NEUROSCIENCE

Formin-Dependent Synaptic Growth: Evidence That Dlar Signals via Diaphanous to Modulate Synaptic Actin and Dynamic Pioneer Microtubules

(2008) C. Pawson et al.   JOURNAL OF NEUROSCIENCE

KIF1Bβ- and KIF1A-mediated axonal transport of presynaptic regulator Rab3 occurs in a GTP-dependent manner through DENN/MADD

(2008) Shinsuke Niwa et al.   NATURE CELL BIOLOGY

Lifeact: a versatile marker to visualize F-actin

(2008) Julia Riedl et al.   NATURE METHODS