Article
Multidisciplinary Sciences
Su-su Bao, Peng-fei Tang, Nan-yong Gao, Zhong-xiang Xiao, Jian-chang Qian, Long Zheng, Guo-xin Hu, Huan-hai Xu
Summary: This study evaluated the effects of apatinib on the pharmacokinetics of tramadol and its main metabolite O-desmethyltramadol, as well as its inhibitory effects on liver microsomes and CYP2D6.1. The findings suggest that apatinib can enhance the analgesic effect of tramadol and O-desmethyltramadol and has a strong inhibitory effect on their metabolism.
Article
Chemistry, Applied
Mu Zhao, Ting Li, Fan Yang, Xinyue Cui, Tingting Zou, Huanlu Song, Ye Liu
Summary: This study characterized the composition of volatile aroma compounds and key aroma-active compounds in dried Hanyuan Zanthoxylum bungeanum. The results identified several key aroma-active compounds such as myrcene and limonene.
Article
Chemistry, Applied
Xuejie Li, Xiangquan Zeng, Huanlu Song, Yu Xi, Yan Li, Bowen Hui, He Li, Jian Li
Summary: GC x GC-O-TOF-MS and GC-IMS have been increasingly used in complex food flavor analysis, but few studies have applied these techniques to identify the aroma components of tomato pastes. This study comprehensively characterized the aroma profiles of cold and hot break tomato pastes using SAFE-GC-O-MS, SAFE-GC x GC-O-TOF-MS, and HS-GC-IMS for the first time. A total of 274 volatile compounds were identified, which is far more than previously reported.
Article
Biochemical Research Methods
O. Yoo, E. K. Y. Tang, M. N. Nguyen, S. Salman, A. J. Hua, B. S. von Ungern Sternberg, L. Y. Lim
Summary: A validated HPLC-UV method was developed for quantifying tramadol and its main metabolite in human plasma in the presence of potentially interfering drugs, and successfully used in analyzing blood samples from 137 pediatric participants in a tramadol pharmacokinetic trial.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2021)
Article
Food Science & Technology
Farhad Niknejad, Laura Escriva, Khoda Berdi Adel Rad, Masoud Khoshnia, Francisco J. Barba, Houda Berrada
Summary: A pilot study conducted in Golestan, Iran investigated the occurrence of 10 mycotoxins in esophageal cancer patients' urine, revealing the presence of 4 mycotoxins. The distribution of different toxins in the control and case groups was identified, highlighting the need for further exploration of the relationship between mycotoxin contamination and esophageal cancer.
Article
Chemistry, Analytical
Purna K. Khatri, Mauro Paolini, Roberto Larcher, Luca Ziller, Dana Alina Magdas, Olivian Marincas, Alberto Roncone, Luana Bontempo
Summary: The combination of GC-MS/MS and GC-IRMS methods is effective to control false declaration in various food matrices, including lavender essential oil. The developed GC-MS/MS method allows for the determination of volatile organic compounds in lavender essential oil, while the GC-IRMS method characterizes the isotope ratios of carbon and hydrogen in the oil. Both methods have been validated and shown to be sensitive, precise, and accurate.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Svante Vikingsson, Shannon T. Krauss, Ruth E. Winecker, Ronald R. Flegel, Eugene D. Hayes
Summary: This study found that one adulterant can interfere with urine drug testing, while the other two had no effect. Synthetic urine is difficult to be identified by tools, but authentic urine with specific biomarkers can be clearly distinguished. These findings provide potential targets for future urine testing screening.
JOURNAL OF ANALYTICAL TOXICOLOGY
(2022)
Article
Environmental Sciences
Sonja A. Wrobel, Stephan Koslitz, Vladimir N. Belov, Daniel Bury, Heiko Hayen, Thomas Bruening, Holger M. Koch, Heiko U. Kaefferlein
Summary: This study developed and validated an analytical method to detect the metabolites of neonicotinoid insecticides in human urine. The results showed that the main metabolite in human urine was 6-chloronicotinic acid glycine, but the specific source of exposure remained unclear.
ENVIRONMENTAL RESEARCH
(2023)
Article
Food Science & Technology
Chujun Liu, Yawen Guo, Bo Wang, Lan Chen, Kaizhou Xie, Chenggen Yang
Summary: A simple and sensitive GC-MS/MS method was developed for screening penicillin G residues in poultry eggs, utilizing an external calibration method and electron impact ionization for analyte separation. The method validation demonstrated good linearity, accuracy, and precision, making it suitable for quantitative analysis.
Article
Chemistry, Applied
Maria Constantinou, Despo Louca-Christodoulou, Agapios Agapiou
Summary: A validated multi-residue method using LC-MS/MS and GC-MS/MS for analyzing various pesticides in raisins was conducted according to DG SANTE guidelines. Results showed the presence of multiple pesticides in conventional samples, while no analyzed pesticides were detected in samples from organic farming. The study highlights the need for official controls on pesticide residues in processed samples, particularly on high consumption dried fruits like raisins.
Article
Environmental Sciences
Andrea Acosta-Dacal, Cristian Rial-Berriel, Ricardo Diaz-Diaz, Maria del Mar Bernal-Suarez, Octavio P. Luzardo
Summary: The modified QuEChERS method optimized for the extraction of 218 pesticide residues in agricultural soil samples showed high accuracy and sensitivity when applied to actual samples. The method demonstrated excellent performance in terms of quantification and detection limits.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Chemistry, Multidisciplinary
Mark Newman, Desmond A. Curran
Summary: This study confirms high agreement between liquid and dried urine hormone results, and finds that four dried spot urine samples can be used as a substitute for 24-h urine collection in measuring reproductive hormones. The ease of handling dried urine samples makes them useful for clinical assessment and large epidemiologic studies.
Article
Biochemical Research Methods
Puran Lal Sahu, Ashok Kumar Maurya, Subhasmita Priyadarshini, Anees Ahmad Siddiqui, Kapendra Sahu
Summary: A simple and sensitive GC-MS/MS method was developed for quantitation of salbutamol in human urine. This method demonstrated high accuracy and precision and can reliably detect salbutamol at or below the recommended concentration.
JOURNAL OF CHROMATOGRAPHIC SCIENCE
(2023)
Article
Biochemical Research Methods
Jiahua Ji, Ying Zhang, Jifen Wang
Summary: Designer drugs of cathinone have been abused, leading to social issues and the need for rapid detection methods. DART-MS/MS was used to develop an effective analysis method for nine synthetic cathinones in human blood and urine.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
(2021)
Article
Biochemical Research Methods
Y. Lan Pham, Ruyi Yu, Jonathan Beauchamp
Summary: The Peppermint Experiment aims to address the lack of comparability in breath biomarker studies by analyzing the washout profiles of peppermint oil constituents in exhaled breath. The experiment involves measuring samples from a group of volunteers using three different analytical platforms. The results show variable washout profiles within and between individuals, indicating differences in absorption, distribution, and metabolism of the constituents. However, the low variability between instruments suggests that discrepancies in benchmark values reported in the literature are mostly due to biological variability rather than method or platform performance.
JOURNAL OF BREATH RESEARCH
(2023)
Review
Chemistry, Multidisciplinary
Mostafa M. Kamal, Abd El-Aziz Y. El-Sayed, Seddique M. Ahmed, Ahmed A. Omran, Mohamed M. Shahata
ARABIAN JOURNAL OF CHEMISTRY
(2015)
Article
Chemistry, Physical
A. H. Naggar, Mohammed El Kaoutit, Ignacio Naranjo-Rodriguez, A. Y. El-Sayed, Jose Luis Hidalgo-Hidalgo de Cisneros
JOURNAL OF SOLUTION CHEMISTRY
(2016)
Article
Engineering, Chemical
Hany H. Abdel Ghafar, Gehad G. Mohamed, Magdy Abd El-Salam, Abdel-Aziz Y. El-Sayed
DESALINATION AND WATER TREATMENT
(2015)
Article
Chemistry, Physical
Ahmed Omran, Abdel-Aziz El-Sayed, Ahmed Shehata
JOURNAL OF SOLUTION CHEMISTRY
(2012)
Article
Materials Science, Multidisciplinary
Osama A. Fouad, Salah A. Makhlouf, Gomaa A. M. Ali, A. Y. El-Sayed
MATERIALS CHEMISTRY AND PHYSICS
(2011)
Article
Spectroscopy
Ahmed A. Omran, Abdel-Aziz El-Sayed, Ahmed Shehata
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2011)
Article
Chemistry, Analytical
Ahmed Hosny Naggar, Mohammed ElKaoutit, Ignacio Naranjo-Rodriguez, Abd El-Aziz Yossef El-Sayed, Jose Luis Hidalgo-Hidalgo de Cisneros
Article
Chemistry, Multidisciplinary
Ahmed K. Yousef, Moustafa Sanad, Mohamed M. Rashad, Abdel-Aziz Y. El-Sayed, Yusuke Ide
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN
(2019)
Article
Physics, Condensed Matter
M. M. S. Sanad, Ahmed K. Yousef, M. M. Rashad, A. H. Naggar, A. Y. El-Sayed
PHYSICA B-CONDENSED MATTER
(2020)
Article
Chemistry, Analytical
Ahmed H. Naggar, Ahmed Kotb, Ahmed A. Gahlan, Mahmoud H. Mahross, Abd El-Aziz Y. El-Sayed, Adel A. Abdelwahab
Summary: A novel material Cu(2)ONPs-C@G was prepared by chemical reduction and intensive mixing, characterized using TEM, SEM, XRD, and CV. The material was used to quantify MEB with SWAdASV, showing good stability and reproducibility, as well as accurate quantification of MEB in tablets and biological fluids such as spiked urine and plasma samples.
Article
Chemistry, Multidisciplinary
Ahmed K. Yousef, Yena Kim, Piyali Bhanja, Peng Mei, Malay Pramanik, M. M. S. Sanad, M. M. Rashad, A. Y. El-Sayed, Abdulmohsen Ali Alshehri, Yousef Gamaan Alghamdi, Khalid Ahmed Alzahrani, Yusuke Ide, Jianjian Lin, Yusuke Yamauchi
Article
Chemistry, Analytical
OA Farghaly, MA Taher, AH Naggar, AY El-Sayed
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2005)
Review
Chemistry, Analytical
AAY El-Sayed, NA El-Salem
ANALYTICAL SCIENCES
(2005)
Article
Chemistry, Analytical
AA Omran, K Kitamura, S Takegami, M Kume, M Yoshida, AAY El-Sayed, MH Mohamed, M Abdel-Mottaleb
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2002)
