Dietary n-3 PUFAs Deficiency Increases Vulnerability to Inflammation-Induced Spatial Memory Impairment

GPR84 deficiency reduces microgliosis, but accelerates dendritic degeneration and cognitive decline in a mouse model of Alzheimer’s disease

(2015) Julie Audoy-Rémus et al.   BRAIN BEHAVIOR AND IMMUNITY

Docosahexaenoic acid (DHA): a modulator of microglia activity and dendritic spine morphology

(2015) Philip Chang et al.   Journal of Neuroinflammation

Microglial Activation Enhances Associative Taste Memory through Purinergic Modulation of Glutamatergic Neurotransmission

(2015) J.-C. Delpech et al.   JOURNAL OF NEUROSCIENCE

Microglia and their CX3CR1 signaling are involved in hippocampal- but not olfactory bulb-related memory and neurogenesis

(2014) Ronen Reshef et al.   BRAIN BEHAVIOR AND IMMUNITY

Nutritional n-3 PUFAs deficiency during perinatal periods alters brain innate immune system and neuronal plasticity-associated genes

(2014) Charlotte Madore et al.   BRAIN BEHAVIOR AND IMMUNITY

Dietary DHA during development affects depression-like behaviors and biomarkers that emerge after puberty in adolescent rats

(2014) Michael J. Weiser et al.   JOURNAL OF LIPID RESEARCH

Polyunsaturated fatty acids and their metabolites in brain function and disease

(2014) Richard P. Bazinet et al.   NATURE REVIEWS NEUROSCIENCE

Microglial CR3 Activation Triggers Long-Term Synaptic Depression in the Hippocampus via NADPH Oxidase

(2014) Jingfei Zhang et al.   NEURON

Transgenic Increase in n-3/n-6 Fatty Acid Ratio Protects Against Cognitive Deficits Induced by an Immune Challenge through Decrease of Neuroinflammation

(2014) Jean-Christophe Delpech et al.   NEUROPSYCHOPHARMACOLOGY

n-3 LCPUFA improves cognition: The young, the old and the sick

(2014) C. Joffre et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Lipid Mediators in the Resolution of Inflammation

(2014) Charles N. Serhan et al.   Cold Spring Harbor Perspectives in Biology

Nutritional omega-3 modulates neuronal morphology in the prefrontal cortex along with depression-related behaviour through corticosterone secretion

(2014) T Larrieu et al.   Translational Psychiatry

The HPA – Immune Axis and the Immunomodulatory Actions of Glucocorticoids in the Brain

(2014) Marc-André Bellavance et al.   Frontiers in Immunology

Adolescent Behavior and Dopamine Availability Are Uniquely Sensitive to Dietary Omega-3 Fatty Acid Deficiency

(2013) Corina O. Bondi et al.   BIOLOGICAL PSYCHIATRY

Early morphofunctional plasticity of microglia in response to acute lipopolysaccharide

(2013) C. Madore et al.   BRAIN BEHAVIOR AND IMMUNITY

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

(2013) Christopher N. Parkhurst et al.   CELL

n-3 Fatty acids, inflammation and immunity: new mechanisms to explain old actions

(2013) Philip C. Calder   PROCEEDINGS OF THE NUTRITION SOCIETY

Omega-6 docosapentaenoic acid-derived resolvins and 17-hydroxydocosahexaenoic acid modulate macrophage function and alleviate experimental colitis

(2012) Cheng-Ying Chiu et al.   INFLAMMATION RESEARCH

Complement activation in the injured central nervous system: another dual-edged sword?

(2012) Faith H Brennan et al.   Journal of Neuroinflammation

Nutritional n-3 polyunsaturated fatty acids deficiency alters cannabinoid receptor signaling pathway in the brain and associated anxiety-like behavior in mice

(2012) Thomas Larrieu et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Cognitive enhancement by omega-3 fatty acids from child-hood to old age: Findings from animal and clinical studies

(2012) Dirk W. Luchtman et al.   NEUROPHARMACOLOGY

Short-Term Long Chain Omega3 Diet Protects from Neuroinflammatory Processes and Memory Impairment in Aged Mice

(2012) Virginie F. Labrousse et al.   PLoS One

C3-dependent mechanism of microglial priming relevant to multiple sclerosis

(2012) V. Ramaglia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

n-3 Polyunsaturated fatty acids in animal models with neuroinflammation

(2012) Sarah K. Orr et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Docosahexaenoic Acid Signalolipidomics in Nutrition: Significance in Aging, Neuroinflammation, Macular Degeneration, Alzheimer's, and Other Neurodegenerative Diseases

(2011) Nicolas G. Bazan et al.   Annual Review of Nutrition

N-Docosahexaenoylethanolamide promotes development of hippocampal neurons

(2011) Hee-Yong Kim et al.   BIOCHEMICAL JOURNAL

Fifteen weeks of dietary n-3 polyunsaturated fatty acid deprivation increase turnover of n-6 docosapentaenoic acid in rat-brain phospholipids

(2011) Miki Igarashi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Long term adequate n-3 polyunsaturated fatty acid diet protects from depressive-like behavior but not from working memory disruption and brain cytokine expression in aged mice

(2011) Aurélie Moranis et al.   BRAIN BEHAVIOR AND IMMUNITY

Chronic dietary intake of α-linolenic acid does not replicate the effects of DHA on passive properties of entorhinal cortex neurons

(2011) Dany Arsenault et al.   BRITISH JOURNAL OF NUTRITION

Dynamics of Retrieval Strategies for Remote Memories

(2011) Inbal Goshen et al.   CELL

Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions

(2011) Mathieu Lafourcade et al.   NATURE NEUROSCIENCE

Microglia activation triggers astrocyte-mediated modulation of excitatory neurotransmission

(2011) O. Pascual et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Accumulation of Dietary Docosahexaenoic Acid in the Brain Attenuates Acute Immune Response and Development of Postischemic Neuronal Damage

(2011) Mélanie Lalancette-Hébert et al.   STROKE

Long-term changes of spine dynamics and microglia after transient peripheral immune response triggered by LPS in vivo

(2011) Satoru Kondo et al.   Molecular Brain

Immune modulation of learning, memory, neural plasticity and neurogenesis

(2010) Raz Yirmiya et al.   BRAIN BEHAVIOR AND IMMUNITY

Bidirectional Regulation of Hippocampal Long-Term Synaptic Plasticity and Its Influence on Opposing Forms of Memory

(2010) G. Malleret et al.   JOURNAL OF NEUROSCIENCE

Mechanisms of n-3 fatty acid-mediated development and maintenance of learning memory performance

(2010) Hui-Min Su   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Docosahexaenoic Acid (DHA) and Docosapentaenoic Acid (DPAn-6) Algal Oils Reduce Inflammatory Mediators in Human Peripheral Mononuclear Cells In Vitro and Paw Edema In Vivo

(2010) Julie M. Nauroth et al.   LIPIDS

The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights

(2010) Agnes E. Coutinho et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Metabolism and biological production of resolvins derived from docosapentaenoic acid (DPAn-6)

(2009) Bindi Dangi et al.   BIOCHEMICAL PHARMACOLOGY

Plasma Transcortin Influences Endocrine and Behavioral Stress Responses in Mice

(2009) Elodie M. Richard et al.   ENDOCRINOLOGY

Docosahexaenoic acid promotes hippocampal neuronal development and synaptic function

(2009) Dehua Cao et al.   JOURNAL OF NEUROCHEMISTRY

Environmental Enrichment Restores Memory Functioning in Mice with Impaired IL-1 Signaling via Reinstatement of Long-Term Potentiation and Spine Size Enlargement

(2009) I. Goshen et al.   JOURNAL OF NEUROSCIENCE

Malaise in the water maze: Untangling the effects of LPS and IL-1β on learning and memory

(2008) Colm Cunningham et al.   BRAIN BEHAVIOR AND IMMUNITY

Uncoupling of interleukin-6 from its signalling pathway by dietary n-3-polyunsaturated fatty acid deprivation alters sickness behaviour in mice

(2008) Rozenn Mingam et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Docosahexaenoic acid prevents lipopolysaccharide-induced cytokine production in microglial cells by inhibiting lipopolysaccharide receptor presentation but not its membrane subdomain localization

(2008) Véronique De Smedt-Peyrusse et al.   JOURNAL OF NEUROCHEMISTRY

Transgenic Mice Lacking NMDAR-Dependent LTD Exhibit Deficits in Behavioral Flexibility

(2008) Russell E. Nicholls et al.   NEURON

From inflammation to sickness and depression: when the immune system subjugates the brain

(2007) Robert Dantzer et al.   NATURE REVIEWS NEUROSCIENCE

Behavioral Deficits Associated with Dietary Induction of Decreased Brain Docosahexaenoic Acid Concentration

(2003) Toru Moriguchi et al.   JOURNAL OF NEUROCHEMISTRY