Detection, treatment, and prevention of carbapenemase-producingEnterobacteriaceae: Recommendations from an International Working Group

Pharmacological Rationale for Antibiotic Treatment of Intra-abdominal Infections

(2014) T. Mazzei et al.   JOURNAL OF CHEMOTHERAPY

Serum Bactericidal Activity of Three Different Dosing Regimens of Colistin with Implications for Optimum Clinical Use

(2014) G.L. Daikos et al.   JOURNAL OF CHEMOTHERAPY

Treatment Outcome of Bacteremia Due to KPC-Producing Klebsiella pneumoniae: Superiority of Combination Antimicrobial Regimens

(2012) Zubair A. Qureshi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Escherichia coli from Italy Producing OXA-48 Carbapenemase Encoded by a Novel Tn1999Transposon Derivative

(2012) Tommaso Giani et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Therapy of 1,025 Severely Ill Patients with Complicated Infections in a German Multicenter Study: Safety Profile and Efficacy of Tigecycline in Different Treatment Modalities

(2012) Klaus-Friedrich Bodmann et al.   CHEMOTHERAPY

Predictors of Mortality in Bloodstream Infections Caused by Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae: Importance of Combination Therapy

(2012) M. Tumbarello et al.   CLINICAL INFECTIOUS DISEASES

High-Dose, Extended-Interval Colistin Administration in Critically Ill Patients: Is This the Right Dosing Strategy? A Preliminary Study

(2012) L. Dalfino et al.   CLINICAL INFECTIOUS DISEASES

Interventional strategies and current clinical experience with carbapenemase-producing Gram-negative bacteria

(2012) M. Akova et al.   CLINICAL MICROBIOLOGY AND INFECTION

Rapid evolution and spread of carbapenemases among Enterobacteriaceae in Europe

(2012) R. Cantón et al.   CLINICAL MICROBIOLOGY AND INFECTION

Carbapenemases in Klebsiella pneumoniae and Other Enterobacteriaceae: an Evolving Crisis of Global Dimensions

(2012) L. S. Tzouvelekis et al.   CLINICAL MICROBIOLOGY REVIEWS

Emergence of resistance to fosfomycin used as adjunct therapy in KPC Klebsiella pneumoniae bacteraemia: report of three cases

(2012) D. E. Karageorgopoulos et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

OXA-48-like carbapenemases: the phantom menace

(2012) L. Poirel et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Evaluation of a DNA microarray for the rapid detection of extended-spectrum  -lactamases (TEM, SHV and CTX-M), plasmid-mediated cephalosporinases (CMY-2-like, DHA, FOX, ACC-1, ACT/MIR and CMY-1-like/MOX) and carbapenemases (KPC, OXA-48, VIM, IMP and NDM)

(2012) G. Cuzon et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Evaluation of the New NucliSENS EasyQ KPC Test for Rapid Detection of Klebsiella pneumoniae Carbapenemase Genes (blaKPC)

(2012) T. Spanu et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Fecal Carriage of Carbapenemase-Producing Enterobacteriaceae: a Hidden Reservoir in Hospitalized and Nonhospitalized Patients

(2012) D. Gijon et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Detection of Carbapenemase Producers in Enterobacteriaceae by Use of a Novel Screening Medium

(2012) P. Nordmann et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Detection of Carbapenemases in Enterobacteriaceae by a Commercial Multiplex PCR

(2012) M. Kaase et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Carbapenem resistance in Enterobacteriaceae: here is the storm!

(2012) Patrice Nordmann et al.   TRENDS IN MOLECULAR MEDICINE

An effective intervention to limit the spread of an epidemic carbapenem-resistant Klebsiella pneumoniae strain in an acute care setting: From theory to practice

(2011) Pnina Ciobotaro et al.   AMERICAN JOURNAL OF INFECTION CONTROL

Pharmacological and Patient-Specific Response Determinants in Patients with Hospital-Acquired Pneumonia Treated with Tigecycline

(2011) Sujata M. Bhavnani et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Multicenter Evaluation of a New DNA Microarray for Rapid Detection of Clinically RelevantblaGenes from β-Lactam-Resistant Gram-Negative Bacteria

(2011) Pierre Bogaerts et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Population Pharmacokinetics of Colistin Methanesulfonate and Formed Colistin in Critically Ill Patients from a Multicenter Study Provide Dosing Suggestions for Various Categories of Patients

(2011) S. M. Garonzik et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Carbapenems: Past, Present, and Future

(2011) Krisztina M. Papp-Wallace et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Incidence of and Risk Factors for Colistin-Associated Nephrotoxicity in a Large Academic Health System

(2011) J. M. Pogue et al.   CLINICAL INFECTIOUS DISEASES

Colistin-Resistant, Klebsiella pneumoniae Carbapenemase (KPC)-Producing Klebsiella pneumoniae Belonging to the International Epidemic Clone ST258

(2011) T. Bogdanovich et al.   CLINICAL INFECTIOUS DISEASES

Predictors of mortality in patients with bloodstream infections caused by KPC-producing Klebsiella pneumoniae and impact of appropriate antimicrobial treatment

(2011) O. Zarkotou et al.   CLINICAL MICROBIOLOGY AND INFECTION

Outbreak of KPC-3-producing, and colistin-resistant, Klebsiella pneumoniae infections in two Sicilian hospitals

(2011) M.L. Mezzatesta et al.   CLINICAL MICROBIOLOGY AND INFECTION

Carbapenemase-producing Klebsiella pneumoniae: (when) might we still consider treating with carbapenems?

(2011) G.L. Daikos et al.   CLINICAL MICROBIOLOGY AND INFECTION

Outcomes in severe sepsis and patients with septic shock: Pathogen species and infection sites are not associated with mortality*

(2011) Jean-Ralph Zahar et al.   CRITICAL CARE MEDICINE

Dosing of colistin—back to basic PK/PD

(2011) Phillip J Bergen et al.   CURRENT OPINION IN PHARMACOLOGY

Surveillance and management of multidrug-resistant microorganisms

(2011) Giovanni Battista Orsi et al.   Expert Review of Anti-Infective Therapy

Therapeutic options for infections withEnterobacteriaceaeproducing carbapenem-hydrolyzing enzymes

(2011) Matthew E Falagas et al.   Future Microbiology

A Multifaceted Intervention Strategy for Eradication of a Hospital-Wide Outbreak Caused by Carbapenem-Resistant Klebsiella pneumoniae in Southern Israel

(2011) Abraham Borer et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Institutional Control Measures to Curtail the Epidemic Spread of Carbapenem-Resistant Klebsiella pneumoniae: A 4-Year Perspective

(2011) Matan J. Cohen et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Activity of tigecycline alone and in combination with colistin and meropenem against Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae strains by time–kill assay

(2011) Spyros Pournaras et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Colistin heteroresistance in carbapenemase-producing Klebsiella pneumoniae

(2011) G. Meletis et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Comparative Evaluation of a Chromogenic Agar Medium, the Modified Hodge Test, and a Battery of Meropenem-Inhibitor Discs for Detection of Carbapenemase Activity in Enterobacteriaceae

(2011) C. Seah et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Dissemination of NDM-1 positive bacteria in the New Delhi environment and its implications for human health: an environmental point prevalence study

(2011) Timothy R Walsh et al.   LANCET INFECTIOUS DISEASES

Emergence of Klebsiella pneumoniae Carbapenemase-Producing Bacteria

(2011) Ryan S. Arnold et al.   SOUTHERN MEDICAL JOURNAL

The emerging NDM carbapenemases

(2011) Patrice Nordmann et al.   TRENDS IN MICROBIOLOGY

Genetic Factors Associated with Elevated Carbapenem Resistance in KPC-Producing Klebsiella pneumoniae

(2010) B. Kitchel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Early Dissemination of NDM-1- and OXA-181-ProducingEnterobacteriaceaein Indian Hospitals: Report from the SENTRY Antimicrobial Surveillance Program, 2006-2007

(2010) Mariana Castanheira et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Steady-State Pharmacokinetics and BAL Concentration of Colistin in Critically Ill Patients After IV Colistin Methanesulfonate Administration

(2010) Roberto Imberti et al.   CHEST

In Vitro Susceptibility to Various Antibiotics of Colistin‐Resistant Gram‐Negative Bacterial Isolates in a General Tertiary Hospital in Crete, Greece

(2010) George Samonis et al.   CLINICAL INFECTIOUS DISEASES

Comparison of disk diffusion, Etest and VITEK2 for detection of carbapenemase‐producing Klebsiella pneumoniae with the EUCAST and CLSI breakpoint systems

(2010) M. Vading et al.   CLINICAL MICROBIOLOGY AND INFECTION

Recognition and prevention of multidrug-resistant Gram-negative bacteria in the intensive care unit

(2010) Lisa L. Maragakis   CRITICAL CARE MEDICINE

Antimicrobial susceptibility of Gram-negative nonurinary bacteria to fosfomycin and other antimicrobials

(2010) George Samonis et al.   Future Microbiology

Resistance to cephalosporins and carbapenems in Gram-negative bacterial pathogens

(2010) Yvonne Pfeifer et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Detection and treatment options for Klebsiella pneumoniae carbapenemases (KPCs): an emerging cause of multidrug-resistant infection

(2010) Elizabeth B. Hirsch et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

fAUC/MIC is the most predictive pharmacokinetic/pharmacodynamic index of colistin against Acinetobacter baumannii in murine thigh and lung infection models

(2010) R. V. Dudhani et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Evaluation of a Commercial Microarray System for Detection of SHV-, TEM-, CTX-M-, and KPC-Type  -Lactamase Genes in Gram-Negative Isolates

(2010) A. Endimiani et al.   JOURNAL OF CLINICAL MICROBIOLOGY

In Vitro Evaluation of Antibiotic Synergy for Polymyxin B-Resistant Carbapenemase-Producing Klebsiella pneumoniae

(2010) A. Elemam et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Evaluation of Updated Interpretative Criteria for CategorizingKlebsiella pneumoniaewith Reduced Carbapenem Susceptibility

(2010) Andrea Endimiani et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Hospital outbreak caused by Klebsiella pneumoniae producing KPC-2 β-lactamase resistant to colistin

(2010) K. Kontopoulou et al.   JOURNAL OF HOSPITAL INFECTION

Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study

(2010) Karthikeyan K Kumarasamy et al.   LANCET INFECTIOUS DISEASES

Cluster of bloodstream infections caused by KPC-2 carbapenemase-producing Klebsiella pneumoniae in Manhattan

(2009) Abhijeet S. Nadkarni et al.   AMERICAN JOURNAL OF INFECTION CONTROL

Prospective Observational Study of the Impact of VIM-1 Metallo- -Lactamase on the Outcome of Patients with Klebsiella pneumoniae Bloodstream Infections

(2009) G. L. Daikos et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vitro Activity of Fosfomycin against blaKPC-Containing Klebsiella pneumoniae Isolates, Including Those Nonsusceptible to Tigecycline and/or Colistin

(2009) A. Endimiani et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Population Pharmacokinetic Analysis of Colistin Methanesulfonate and Colistin after Intravenous Administration in Critically Ill Patients with Infections Caused by Gram-Negative Bacteria

(2009) D. Plachouras et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Elucidation of the Pharmacokinetic/Pharmacodynamic Determinant of Colistin Activity against Pseudomonas aeruginosa in Murine Thigh and Lung Infection Models

(2009) R. V. Dudhani et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Characterization of a New Metallo- -Lactamase Gene, blaNDM-1, and a Novel Erythromycin Esterase Gene Carried on a Unique Genetic Structure in Klebsiella pneumoniae Sequence Type 14 from India

(2009) D. Yong et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Nephrotoxicity of Colistin: New Insight into an Old Antibiotic

(2009) Matthew E. Falagas et al.   CLINICAL INFECTIOUS DISEASES

Intravenous fosfomycin for the treatment of nosocomial infections caused by carbapenem-resistant Klebsiella pneumoniae in critically ill patients: a prospective evaluation

(2009) A. Michalopoulos et al.   CLINICAL MICROBIOLOGY AND INFECTION

Risk factors associated with the isolation of colistin-resistant Gram-negative bacteria: A matched case-control study

(2009) Dimitrios K. Matthaiou et al.   CRITICAL CARE MEDICINE

Risk Factors and Clinical Impact of Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae

(2009) Leanne B. Gasink et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Tigecycline possibly underdosed for the treatment of pneumonia: a pharmacokinetic viewpoint

(2009) Olaf Burkhardt et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Colistin therapy for microbiologically documented multidrug-resistant Gram-negative bacterial infections: a retrospective cohort study of 258 patients

(2009) Matthew E. Falagas et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Characterization of blaKPC-containing Klebsiella pneumoniae isolates detected in different institutions in the Eastern USA

(2009) Andrea Endimiani et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Emergence of blaKPC-containing Klebsiella pneumoniae in a long-term acute care hospital: a new challenge to our healthcare system

(2009) A. Endimiani et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Molecular mechanisms disrupting porin expression in ertapenem-resistant Klebsiella and Enterobacter spp. clinical isolates from the UK

(2009) M. Doumith et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Detecting VIM-1 Production in Proteus mirabilis by an Imipenem-Dipicolinic Acid Double Disk Synergy Test

(2009) V. Miriagou et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Sensitive Screening Tests for Suspected Class A Carbapenemase Production in Species of Enterobacteriaceae

(2009) F. Pasteran et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Doripenem

(2009) Gary D. Overturf   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Clinical and Microbiological Outcomes of Serious Infections with Multidrug-Resistant Gram-Negative Organisms Treated with Tigecycline

(2008) K. B. Anthony et al.   CLINICAL INFECTIOUS DISEASES

Colistin serum concentrations after intravenous administration in critically ill patients with serious multidrug-resistant, gram-negative bacilli infections: A prospective, open-label, uncontrolled study

(2008) Nikolaos Markou et al.   CLINICAL THERAPEUTICS

Outcomes of Carbapenem-Resistant Klebsiella pneumoniae Infection and the Impact of Antimicrobial and Adjunctive Therapies

(2008) Gopi Patel et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Metallo-β-lactamases in Gram-negative bacteria: introducing the era of pan-resistance?

(2008) Helen C. Maltezou   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Tigecycline for the treatment of multidrug-resistant Enterobacteriaceae: a systematic review of the evidence from microbiological and clinical studies

(2008) Theodoros Kelesidis et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Evaluation of different laboratory tests for the detection of metallo- -lactamase production in Enterobacteriaceae

(2008) I. Galani et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

In vitro pharmacodynamics of colistin against multidrug-resistant Klebsiella pneumoniae

(2008) A. Poudyal et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Evaluation of CHROMagar KPC for Rapid Detection of Carbapenem-Resistant Enterobacteriaceae

(2008) Z. Samra et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Evaluation of Boronic Acid Disk Tests for Differentiating KPC-Possessing Klebsiella pneumoniae Isolates in the Clinical Laboratory

(2008) A. Tsakris et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Extended-spectrum β-lactamase-producing Enterobacteriaceae: an emerging public-health concern

(2008) Johann DD Pitout et al.   LANCET INFECTIOUS DISEASES