Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 55, Issue 9, Pages 4457-4460Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00353-11
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Funding
- Belgian Antibiotic Policy Coordination Committee (BAPCOC)
- Ministry of Public Health, Belgium
- European Community [2009-241742]
- INSERM, France
- Ministere de l'Education Nationale et de la Recherche [UPRES-EA3539]
- Universite Paris XI, Paris, France
- National Institutes of Health [AI072219, AI063517]
- Geriatric Research Education and Clinical Center
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A new commercial low-density microarray which identifies common extended-spectrum beta-lactamase plasmid-mediated cephalosporinase genes, as well as carbapenemase (bla(KPC) and bla(NDM)) genes, was evaluated. We tested 207 clinical and reference/collection isolates of the Enterobacteriaceae possessing different bla genes. Overall, the sensitivity and specificity of the microarray were 100% for the detection of the plasmid-mediated bla(AmpC), bla(KPC), and bla(NDM) genes using bla gene sequencing as the reference method.
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