Avoiding antibody aggregation during processing: Establishing hold times

Analysis of Protein Aggregation in Neurodegenerative Disease

(2013) Jeppe T. Pedersen et al.   ANALYTICAL CHEMISTRY

On-line characterization of monoclonal antibody variants by liquid chromatography–mass spectrometry operating in a two-dimensional format

(2011) Melissa Alvarez et al.   ANALYTICAL BIOCHEMISTRY

Aggregates in monoclonal antibody manufacturing processes

(2011) María Vázquez-Rey et al.   BIOTECHNOLOGY AND BIOENGINEERING

Nonnative Aggregation of an IgG1 Antibody in Acidic Conditions: Part 1. Unfolding, Colloidal Interactions, and Formation of High-Molecular-Weight Aggregates

(2011) Rebecca K. Brummitt et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Aggregation Stability of a Monoclonal Antibody During Downstream Processing

(2011) Paolo Arosio et al.   PHARMACEUTICAL RESEARCH

Acid-Induced Aggregation of Human Monoclonal IgG1 and IgG2: Molecular Mechanism and the Effect of Solution Composition

(2010) Sanjay B. Hari et al.   BIOCHEMISTRY

Impact of antibody aggregation on a flowthrough anion-exchange membrane process

(2010) Ajay R. Lajmi et al.   BIOTECHNOLOGY PROGRESS

Recovery and purification process development for monoclonal antibody production

(2010) Hui F. Liu et al.   mAbs

Charge variants in IgG1

(2010) Leslie A. Khawli et al.   mAbs

Biopharmaceutical benchmarks 2010

(2010) Gary Walsh   NATURE BIOTECHNOLOGY

Reduced elimination of IgG antibodies by engineering the variable region

(2010) T. Igawa et al.   PROTEIN ENGINEERING DESIGN & SELECTION

The use of native cation-exchange chromatography to study aggregation and phase separation of monoclonal antibodies

(2010) Shuang Chen et al.   PROTEIN SCIENCE

Recent advances in large-scale production of monoclonal antibodies and related proteins

(2010) Abhinav A. Shukla et al.   TRENDS IN BIOTECHNOLOGY

Analysis of charge heterogeneities in mAbs using imaged CE

(2009) Xiaoping Z. He et al.   ELECTROPHORESIS

Aqueous two-phase systems: A viable platform in the manufacturing of biopharmaceuticals

(2009) P.A.J. Rosa et al.   JOURNAL OF CHROMATOGRAPHY A

Follow-on protein products: scientific issues, developments and challenges

(2009) Anurag S. Rathore   TRENDS IN BIOTECHNOLOGY

Heterogeneity of Monoclonal Antibodies Revealed by Charge-Sensitive Methods

(2008) J. Vlasak et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY