Early oligomerization stages for the non-amyloid component of α-synuclein amyloid

Difference in dimer conformation between amyloid-β(1–42) and (1–43) proteins: Replica exchange molecular dynamics simulations in water

(2014) Atsushi Yano et al.   CHEMICAL PHYSICS LETTERS

Molecular Structures of Amyloid and Prion Fibrils: Consensus versus Controversy

(2013) Robert Tycko et al.   ACCOUNTS OF CHEMICAL RESEARCH

Comparative Molecular Dynamics Study of Human Islet Amyloid Polypeptide (IAPP) and Rat IAPP Oligomers

(2013) Guizhao Liang et al.   BIOCHEMISTRY

Computational Assembly of Polymorphic Amyloid Fibrils Reveals Stable Aggregates

(2013) Mohamed Raef Smaoui et al.   BIOPHYSICAL JOURNAL

Novel Mechanistic Insight into the Molecular Basis of Amyloid Polymorphism and Secondary Nucleation during Amyloid Formation

(2013) Jae Sun Jeong et al.   JOURNAL OF MOLECULAR BIOLOGY

The Dynamic Structure of α-Synuclein Multimers

(2013) Thomas Gurry et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Effect of α-Synuclein on Amyloid β-Induced Toxicity: Relevance to Lewy Body Variant of Alzheimer Disease

(2013) Rosa Resende et al.   NEUROCHEMICAL RESEARCH

Meta-analysis of the insulin degrading enzyme polymorphisms and susceptibility to Alzheimer's disease

(2013) Yunyun Zhang et al.   NEUROSCIENCE LETTERS

Toxic prefibrillar α-synuclein amyloid oligomers adopt a distinctive antiparallel β-sheet structure

(2012) María Soledad Celej et al.   BIOCHEMICAL JOURNAL

Simulation Studies on the Stabilities of Aggregates Formed by Fibril-Forming Segments of α-Synuclein

(2012) Jeseong Yoon et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Regulation of α-synuclein expression in down syndrome

(2012) Narayan Ramakrishna et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Distinct Dimerization for Various Alloforms of the Amyloid-Beta Protein: Aβ1–40, Aβ1–42, and Aβ1–40(D23N)

(2012) Sébastien Côté et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Dimer Formation Enhances Structural Differences between Amyloid β-Protein (1–40) and (1–42): An Explicit-Solvent Molecular Dynamics Study

(2012) Bogdan Barz et al.   PLoS One

Distinct Morphologies for Amyloid Beta Protein Monomer: Aβ1–40, Aβ1–42, and Aβ1–40(D23N)

(2011) Sébastien Côté et al.   Journal of Chemical Theory and Computation

Structure and Thermodynamics of Amylin Dimer Studied by Hamiltonian-Temperature Replica Exchange Molecular Dynamics Simulations

(2011) Rozita Laghaei et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Explaining the Structural Plasticity of α-Synuclein

(2011) Orly Ullman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Clustering and Spatial Arrangement of β-Sheet Sequence, but Not Order, Govern α-Synuclein Fibrillogenesis

(2010) Jae-Eun Suk et al.   BIOCHEMISTRY

SPARTA+: a modest improvement in empirical NMR chemical shift prediction by means of an artificial neural network

(2010) Yang Shen et al.   JOURNAL OF BIOMOLECULAR NMR

Spontaneous formation of polyglutamine nanotubes with molecular dynamics simulations

(2010) Rozita Laghaei et al.   JOURNAL OF CHEMICAL PHYSICS

Effect of the Disulfide Bond on the Monomeric Structure of Human Amylin Studied by Combined Hamiltonian and Temperature Replica Exchange Molecular Dynamics Simulations

(2010) Rozita Laghaei et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Effects of G33A and G33I Mutations on the Structures of Monomer and Dimer of the Amyloid-β Fragment 29−42 by Replica Exchange Molecular Dynamics Simulations

(2010) Yan Lu et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Elucidation of Amyloid β-Protein Oligomerization Mechanisms: Discrete Molecular Dynamics Study

(2010) B. Urbanc et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A novel mechanism of non-Aβ component of Alzheimer's disease amyloid (NAC) neurotoxicity. Interplay between p53 protein and cyclin-dependent kinase 5 (Cdk5)

(2010) Anna Kaźmierczak et al.   NEUROCHEMISTRY INTERNATIONAL

Inhibiting α-Synuclein Oligomerization by Stable Cell-Penetrating β-Synuclein Fragments Recovers Phenotype of Parkinson's Disease Model Flies

(2010) Ronit Shaltiel-Karyo et al.   PLoS One

Pre-fibrillar α-synuclein variants with impaired β-structure increase neurotoxicity in Parkinson's disease models

(2009) Damla Pinar Karpinar et al.   EMBO JOURNAL

Curvature Dynamics of α-Synuclein Familial Parkinson Disease Mutants

(2009) Jason D. Perlmutter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Reorganization of α-Synuclein at Low pH Observed by NMR and REMD Simulations

(2009) Kuen-Phon Wu et al.   JOURNAL OF MOLECULAR BIOLOGY

Structures and Thermodynamics of Alzheimer’s Amyloid-β Aβ(16−35) Monomer and Dimer by Replica Exchange Molecular Dynamics Simulations: Implication for Full-Length Aβ Fibrillation

(2009) Yassmine Chebaro et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Improved prediction of protein side-chain conformations with SCWRL4

(2009) Georgii G. Krivov et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Molecular mechanisms of α-synuclein neurodegeneration

(2008) Elisa A. Waxman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Role of the Region 23-28 in Aβ Fibril Formation: Insights from Simulations of the Monomers and Dimers of Alzheimers Peptides Aβ40 and Aβ42

(2008) Adrien Melquiond et al.   Current Alzheimer Research

Energy landscapes of the monomer and dimer of the Alzheimer’s peptide Aβ(1–28)

(2008) Xiao Dong et al.   JOURNAL OF CHEMICAL PHYSICS

Structural Characteristics of α-Synuclein Oligomers Stabilized by the Flavonoid Baicalein

(2008) Dong-Pyo Hong et al.   JOURNAL OF MOLECULAR BIOLOGY

α-Synuclein enhances secretion and toxicity of amyloid beta peptides in PC12 cells

(2008) Anna Kazmierczak et al.   NEUROCHEMISTRY INTERNATIONAL

The fold of  -synuclein fibrils

(2008) M. Vilar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational Equilibria in Monomeric α-Synuclein at the Single-Molecule Level

(2008) Massimo Sandal et al.   PLOS BIOLOGY