Journal
JOURNAL OF CHEMICAL PHYSICS
Volume 133, Issue 3, Pages -Publisher
AMER INST PHYSICS
DOI: 10.1063/1.3431756
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Funding
- NIH, Center for Information Technology
- Eunice Kennedy Shriver National Institute of Child Health and Human Development
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This study is devoted to unbiased motion of a point Brownian particle in a tube with corrugated walls made of conical sections of a varying length. Effective one-dimensional description in terms of the generalized Fick-Jacobs equation is used to derive a formula which gives the effective diffusion coefficient of the particle as a function of the geometric parameters of the tube. Comparison with the results of Brownian dynamics simulations allows us to establish the domain of applicability of both the one-dimensional description and the formula for the effective diffusion coefficient. (C) 2010 American Institute of Physics. [doi:10.1063/1.3431756]
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