Article
Chemistry, Physical
Sania Amjad, Saadia Shaukat, Hafiz Muhammad Abd Ur Rahman, Muhammad Usman, Zahoor H. Farooqi, Muhammad Faizan Nazar
Summary: This study focuses on the interaction between cationic dye methylene blue (MB) and anionic surfactant sodium dodecyl sulfate (SDS), as well as its mixed micelles with nonionic surfactant Triton X-114 (TX-114). The results show that the mixed micellar system is more effective in removing and solubilizing MB from aqueous systems. However, an increase in the concentration of the nonionic surfactant weakens the dye-surfactant interaction in the ionic-nonionic mixed micellar system.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Engineering, Chemical
Xue Liang, Jun Dong, Weihong Zhang, Yanyang Mo, Yan Li, Jing Bai
Summary: This study investigates the solubilization of chlorinated hydrocarbons using synthesized anionic-nonionic gemini surfactants (GEOnS-m) in an aquifer. The results show that the solubilization rate increases with the decrease of ethylene oxide content (EO) of the surfactant molecules, and the solubilization process and form depend on the polarity of the chlorinated hydrocarbons. The study advances the application of anionic-nonionic gemini surfactants in surfactant-enhanced aquifer remediation (SEAR) for chlorinated hydrocarbon solubilization, providing important insights for the design and modeling of such processes.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)
Article
Chemistry, Physical
Rohi Masrat, Kowsar Majid
Summary: This study investigates the solubilization ability of mixed systems of polymers and surfactant micelles on PAHs. It is found that the addition of anionic polymers can accelerate the solubilization ability of cationic surfactant micelles, while delaying the solubilization ability of nonionic surfactant micelles. Additionally, the solubilization capacity of the mixed systems is enhanced as the polymer concentration increases within a certain range.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Chemistry, Physical
Mudussar Ali, Muhammad Usman, Afzal Shah, Abdul Rehman
Summary: Organic dyes, particularly those with hydrophobic properties, face solubility challenges in water-based applications. This study explores the use of various anionic and cationic surfactants to enhance the solubility and stability of a cationic dye, with spectrophotometric data providing insights into partition coefficients and binding constants. Additionally, the study examines the differences between mixed micellar media and solo surfactant systems in terms of binding and partitioning abilities, highlighting the synergistic effects between cationic and anionic components.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Engineering, Chemical
Sedigheh Saddat Moosavi, Amin Reza Zolghadr
Summary: The adsorption of surfactants on amorphous SiO2 surfaces can alter the solid surface structure, change the surface charge density, and lead to the separation of cationic and anionic portions near amorphous SiO2.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2022)
Article
Chemistry, Organic
Kohei Sato, Shoko Tanaka, Junzhen Wang, Kenya Ishikawa, Shugo Tsuda, Tetsuo Narumi, Taku Yoshiya, Nobuyuki Mase
Summary: The novel late-stage solubilization of peptides using hydrazides involves attaching a solubilizing tag through selective N-alkylation at a hydrazide moiety. The tag, which can tolerate ligation and desulfurization conditions, can be detached through a Cu-mediated selective oxidative hydrolysis of the N-alkyl hydrazide. This method was validated through the synthesis of HIV-1 protease.
Article
Chemistry, Physical
Wenning Zhou, Long Jiang, Xunliang Liu, Yang Hu, Yuying Yan
Summary: The study found that mixed surfactants exhibit superior performance by attracting and reducing repulsion between molecules to improve interfacial properties. Controlling the number of ethylene oxide groups can prevent surfactant aggregation and enhance interfacial performance. The positive charge of DTAC molecules shows strong repulsion to salt ions, increasing the overall salt resistance of mixed surfactants.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Environmental Sciences
Qingguo Wang, Lina Tuo, Gang Zhou, Yuanyuan Zhang, Xu Geng, Fasong Zhang, Yonghe Li
Summary: The study revealed that adding nonionic silicones to surfactant solutions can effectively reduce surface tension and wetting time, but has varying effects on foam performance. The difference mainly stems from the different electronegativity between the head groups of anionic and nonionic surfactants, affecting the insertion of nonionic silicones in the liquid film, thus altering foam performance.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Green & Sustainable Science & Technology
Xue Liang, Yan Li, Jing Bai, Jun Dong, Wende Li, Yanyang Mo, Dihan Jiang, Weihong Zhang
Summary: In this study, a series of environment-friendly anionic-nonionic gemini surfactants were synthesized and evaluated for their application in surfactant-enhanced aquifer remediation. The results showed that these surfactants had high critical micelle concentrations and molar solubilization ratios. Inorganic salts could enhance the solubilization capacity of the surfactants. GEO3S-12 was identified as the preferred surfactant for surfactant-enhanced aquifer remediation.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Green & Sustainable Science & Technology
Yu Yao, Yufeng Fu, Li Zhang, Lishuang Xuan, Chuanyu Qin
Summary: In this study, a novel and green Gemini surfactant, SNE(10)SID, was synthesized for the remediation of dense non-aqueous phase liquid-contaminated groundwater. The surfactant exhibited excellent activity under low temperature and high salt conditions, and showed a low adsorption loss. It also demonstrated a significantly higher PCE desorption ability compared to other monomeric surfactants. The total PCE removal rate reached 87.5% after 10 pore volumes of flushing.
JOURNAL OF CLEANER PRODUCTION
(2022)
Article
Engineering, Environmental
Kai Ge, Raphael Paus, Vera Penner, Gabriele Sadowski, Yuanhui Ji
Summary: This study determined the solubility of naproxen and indomethacin under different conditions and proposed a micellar solubilization model and pH-dependent solubility model to describe the solubility of APIs in biorelevant media. The strategy provided theoretical guidance for API formulation development.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Physical
Zizhao Wang, Caili Dai, Jiawei Liu, Yunbo Dong, Jinming Liu, Ning Sun, Lin Li
Summary: This study investigates the synergistic effect and enhanced oil recovery potential of a compound surfactant system composed of N, N-dihydroxyethyl alkyl amide (CDEA) and Alkylphenol polyoxyethylene carboxylate (APEC). The results reveal the importance of compound surfactant systems in EOR, as they can increase surface density, improve interfacial activity, and decrease interfacial tension, leading to enhanced oil recovery and higher oil displacement efficiency. The study also highlights the significance of understanding the interactions between surfactant molecules for practical application and optimization in oilfield development.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Article
Construction & Building Technology
Yogiraj Sargam, Kejin Wang, Ayuna Tsyrenova, Fei Liu, Shan Jiang
Summary: Different surfactants were used to disperse nanosilica in cement pore solution, with results showing that nonionic surfactants led to improved dispersibility and linear increase in compressive strength of cement-nanosilica pastes. Among all surfactants, Triton X-405 had the highest critical micelle concentration and resulted in the highest strength increase attributed to the nucleation of CSH gel and densification with calcite nanocrystals.
CEMENT AND CONCRETE RESEARCH
(2021)
Article
Thermodynamics
Bruna Michele Arruda de Brito Buriti, Maria Eduarda Barsosa, Josue da Silva Buriti, Juliana de Melo Cartaxo, Heber Sivini Ferreira, Gelmires de Araujo Neves
Summary: This study aimed to synthesize and characterize organically modified palygorskite clay using cationic and nonionic surfactants for potential usage in oil-based drilling fluids. The results showed that the organophilization process was effective, and the modified clay displayed good rheological properties and thermal stability at high temperatures, making it suitable as an additive in oil-based drilling fluids.
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
(2022)
Article
Chemistry, Physical
Masaaki Akamatsu, Tatsuki Morita, Kazuki Kobayashi, Hiroki Iwase, Kenichi Sakai, Hideki Sakai
Summary: This study aimed to control the recombination rate of lophyl radicals in micelles formed by cationic surfactants with different alkyl chain lengths. The results showed that the recombination rate was enhanced in micellar solutions with shorter alkyl chain surfactants compared to those with longer alkyl chain surfactants. Small-angle neutron scattering measurements revealed that elliptical micelles were formed in mixtures of the surfactant and the lophine dimer derivative, with a smaller inner volume observed when shorter chain surfactants were used. Evaluation of kinetic parameters indicated a higher randomness of the lophyl radicals in the micelles with shorter surfactant chains. These findings suggest that the size of the confined space formed by the micelles plays a crucial role in determining the recombination rate of lophyl radicals.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Chemistry, Applied
Parvaiz Ahmad Bhat, Nighat Nazir, Oyais Ahmad Chat, Aijaz Ahmad Dar
Summary: The chemical instability of Citral in acidic conditions can be overcome by stabilizing it using mixed surfactant or polymer-amphiphile systems with significant positive charge and oxyethylene content in their single components. The study found that adjusting the cationic surfactants and nonionic surfactants at the interface of self-assembly can effectively stabilize Citral and increase its half-life. The hybrid of Chitosan and P123 showed significant inhibitory effects on Citral degradation.
Article
Biochemistry & Molecular Biology
Muzaffar Hussain Najar, Oyais Ahmad Chat, Parvaiz Ahmad Bhat, Mohammad Amin Mir, Ghulam Mohamamd Rather, Aijaz Ahmad Dar
Summary: In this study, the interactions between a series of bile salts and trypsin were investigated using multiple techniques. The results showed that bile salts with higher hydrophobicity had stronger interactions with trypsin, leading to significant unfolding of the protein. The findings contribute to a better understanding of hydrophobicity-driven unfolding of proteins aided by biological surfactants like bile salts.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Physical
Suraya Jabeen, Mohd Sajid Lone, Saima Afzal, Pawandeep Kour, Arjumund Shaheeen, Firdaus Ahmad Ahanger, Ghulam Mohammad Rather, Aijaz Ahmad Dar
Summary: The study investigated the interactions between a water-soluble anionic polymer and a cationic amphiphile under different conditions, revealing significant differences in the ions provided by NaCl and NaSl. The effects were analyzed through tensiometric, conductometric, and rheometric measurements, showing variations in physicochemical properties.
COLLOID AND POLYMER SCIENCE
(2021)
Article
Chemistry, Applied
Pawandeep Kour, Saima Afzal, Adil Gani, Mohammed Iqbal Zargar, Umar Nabi Tak, Showkat Rashid, Aijaz Ahmad Dar
Summary: Nanoemulsion encapsulated in ionotropic hybrid hydrogel beads of alginate, chitosan, gelatin and polyethylene oxide can effectively deliver hydrophobic active ingredients like curcumin, enhancing their bioavailability and biological activities. The release behavior in simulated gastric and intestinal fluids showed faster release in gastric fluid, potentially due to mesh size, hydration extent, and interaction with Ca2+ ions. The released curcumin in gastric fluid showed significantly greater free radical scavenging and antibacterial activities compared to intestinal fluid.
Article
Chemistry, Physical
Hina Kouser Qadri, Arjumund Shaheen, Showkat Rashid, Imtiyaz Ahmad Bhat, Ghulam Mohammad Rather, Aijaz Ahmad Dar
Summary: In this study, the mixed micelle and monolayer formation of a biocompatible and cleavable gemini surfactant 16-E1-16 with the copolymer P123 were investigated. Strong interaction between P123 and 16-E1-16 was observed, resulting in the formation of small mixed micelles with similar composition and thermodynamically stable mixed monolayers. The formulations of binary mixtures of P123 and 16-E1-16 showed better injectable properties and faster drug release rate, making them potential candidates for injectable drug delivery systems.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Chemistry, Physical
Haamid Rasool Bhat, Malay Kumar Rana, Aijaz Ahmad Dar
Summary: The study investigates the capability of the Cucurbit [n]uril molecule family to capture and sense toxic chemical warfare agents using density functional theory and time-dependent density functional theory. The results demonstrate that CB[6] has good binding stability with the nerve agent cyclosarin, but the stability decreases with an increase in the number of cyclosarin guests. Infrared spectroscopic vibrational signatures and fluorescence spectra analysis confirm the stability of the inclusion complexes and the importance of the NBD fluorophore.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Chemistry, Multidisciplinary
Rohi Masrat, Aijaz Ahmad Dar
Summary: The rheological behavior of aqueous solutions of biocompatible polymer HPC in the presence of cationic CTAB and nonionic Tween 40 has been investigated. Steady-state bulk experiments show two distinct regions in the rheogram, while dynamic experiments indicate a decrease in the stability of HPC hydrogels with increasing surfactant concentration. Interfacial shear tests reveal a non-Newtonian dilatant behavior at the solution-air interface and two distinct dilatant regions separated by a Newtonian region at the solution-soya oil interface. The strength of films formed at the two interfaces decreases with the increase of surfactant concentration, indicating stronger interaction between HPC and CTAB than Tween 40.
Article
Chemistry, Multidisciplinary
Masrat Bashir, Aijaz A. Dar, Imtiyaz Yousuf
Summary: This study synthesized and characterized Mn(II)- and Zn(II)-based complexes 1 and 2 derived from the aroyl-hydrazone Schiff base ligand (L1). The compounds were fully characterized using various analytical techniques. In vitro interaction studies with ct-DNA and bovine serum albumin (BSA) showed that complex 2 exhibited stronger binding than complex 1 and L1. The Mn(II) complex demonstrated better antioxidant ability, while complex 2 showed more effective bactericidal activity against Gram-positive bacteria. In terms of cytotoxicity, the polymeric Zn(II) complex exhibited better and selective cytotoxicity against the A549 cancer cell line.
Article
Biochemistry & Molecular Biology
Umar Nabi Tak, Showkat Rashid, Pawandeep Kour, Nighat Nazir, Mohammed Iqbal Zargar, Aijaz Ahmad Dar
Summary: An ultra-stretchable, quickly self-healable adhesive hydrogel loaded with Bergenia stracheyi extract demonstrates potential for use as wound dressing material. The hydrogel, synthesized using biocompatible and biodegradable polymers and the plant extract, exhibits excellent tissue adhesion, stretchability, mechanical strength, anti-bacterial capability, and anti-oxidant properties. These properties make the hydrogel suitable for biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Food Science & Technology
Pawandeep Kour, Aijaz Ahmad Dar
Summary: The development of hybrid formulations incorporating hydrogels, antioxidants, and nanoemulsions containing polyunsaturated fatty acids is in high demand. In this study, we formulated quercetin-loaded oil-in-water nanoemulsions using surfactants such as Tween 20 (nonionic), sodium lauroyl sarcosine (anionic), and 3-(N,N-dimethylmyristylammonio)-propanesulfonate (zwitterionic) to control autoxidative degradation of linoleic acid. The nanoemulsions with anionic and zwitterionic surfactants exhibited better control of lipid peroxidation at 37 degrees C, with droplet sizes less than 200 nm. The hybrid alginate capsules derived from these formulations showed good release of quercetin and scavenging activity against DPPH radicals, making them robust and suitable for applications in the food and pharmaceutical industries.
ACS FOOD SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Masrat Bashir, Aijaz A. Dar, Imtiyaz Yousuf
Summary: This work focuses on the synthesis, characterization, and biological profile of Mn(II)- and Zn(II)-based complexes derived from a specific ligand. The structural and electronic properties were studied, and the stability of crystal lattice structures was investigated. The complexes showed avid binding to DNA and exhibited antioxidant and antibacterial activities. Furthermore, the polymeric Zn(II) complex exhibited selective cytotoxicity against a lung cancer cell line.
Article
Nanoscience & Nanotechnology
Nirbhai Singh, Shikha Aery, Smayira Juneja, Laxmi Kumari, Mohd Sajid Lone, Aijaz Ahmad Dar, Sandip Pawar, Surinder K. Mehta, Abhijit Dan
Summary: This study presents a promising strategy for drug delivery using chitosan hydrogels and dual-responsive microgels. The composite materials showed controllable release of the drug and excellent biocompatibility.
ACS APPLIED BIO MATERIALS
(2022)
Article
Nanoscience & Nanotechnology
Nirbhai Singh, Shikha Aery, Smayira Juneja, Laxmi Kumari, Mohd Sajid Lone, Aijaz Ahmad Dar, Sandip V. Pawar, Surinder K. Mehta, Abhijit Dan
Summary: A promising strategy based on chitosan hydrogels and dual temperature- and pH-responsive microgels was reported for the release of a model drug, moxifloxacin. The microgels were incorporated inside the hydrogel matrix, resulting in a double barrier system that significantly reduced the drug release rate and prolonged the delivery time. The release of moxifloxacin could be controlled by regulating the temperature and pH of the delivery medium.
ACS APPLIED BIO MATERIALS
(2022)
Article
Veterinary Sciences
Mujeeb Ur Rehman Fazili, Aijaz Ahmad Dar, Akeel Bashir Beigh, Anees Ahmad Shah, Rameez Ali Dar
Summary: The study concludes that the modified intralingual suture technique is minimally invasive, cost-effective, suitable for field application, and more acceptable to farmers/animal owners for treating cross-sucking in heifers.
ACTA VETERINARIA EURASIA
(2022)
Article
Chemistry, Organic
Mohmad Muzafar Wani, Aijaz Ahmad Dar, Bilal A. Bhat
Summary: This study presents a novel Morita-Baylis-Hillman reaction utilizing electron-deficient alkenes in micellar media for the synthesis of a wide range of aryl and aliphatic ketones. The reaction takes place in water under mild conditions within the confined environment of micelles, aligning with the principles of sustainable and green chemistry. Detailed proton NMR studies establish the site of the reaction in the palisade region of the micellar assembly, suggesting the potential of employing micellar catalysis for energetically less favorable chemical transformations.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2022)
