The Dynamics of the Mitochondrial Organelle as a Potential Therapeutic Target

Transcriptional control of mitochondrial biogenesis and its interface with inflammatory processes

(2012) Claude A. Piantadosi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

RETRACTED: Dynamic changes of mitochondrial fission proteins after transient cerebral ischemia in mice

(2012) Wentao Liu et al.   BRAIN RESEARCH

Inhibition of Drp1 provides neuroprotection in vitro and in vivo

(2012) J Grohm et al.   CELL DEATH AND DIFFERENTIATION

RETRACTED: Mitochondrial Dynamics, Biogenesis, and Function Are Coordinated with the Cell Cycle by APC/CCDH1

(2012) Assegid Garedew et al.   Cell Metabolism

SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function

(2012) Nathan L. Price et al.   Cell Metabolism

Mitochondrial-Associated Metabolic Changes and Neurodegeneration in Huntingtons Disease - from Clinical Features to the Bench

(2012) Tatiana R. Rosenstock et al.   CURRENT DRUG TARGETS

Sensing endoplasmic reticulum stress by protein kinase RNA-like endoplasmic reticulum kinase promotes adaptive mitochondrial DNA biogenesis and cell survival via heme oxygenase-1/carbon monoxide activity

(2012) Min Zheng et al.   FASEB JOURNAL

LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1

(2012) X. Wang et al.   HUMAN MOLECULAR GENETICS

Mitochondrial division ensures the survival of postmitotic neurons by suppressing oxidative damage

(2012) Yusuke Kageyama et al.   JOURNAL OF CELL BIOLOGY

PINK1- and Parkin-mediated mitophagy at a glance

(2012) Seok Min Jin et al.   JOURNAL OF CELL SCIENCE

Parkinson’s disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction

(2012) Xinglong Wang et al.   JOURNAL OF NEUROCHEMISTRY

Mitochondrial biogenesis contributes to ischemic neuroprotection afforded by LPS pre-conditioning

(2012) R. Anne Stetler et al.   JOURNAL OF NEUROCHEMISTRY

Mitochondrial Dynamics and Bioenergetic Dysfunction Is Associated with Synaptic Alterations in Mutant SOD1 Motor Neurons

(2012) J. Magrane et al.   JOURNAL OF NEUROSCIENCE

Dynamic changes of mitochondrial fusion and fission proteins after transient cerebral ischemia in mice

(2012) Wentao Liu et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Exercise induces mitochondrial biogenesis after brain ischemia in rats

(2012) Q. Zhang et al.   NEUROSCIENCE

A perspective on the determination of mitochondrial biogenesis

(2011) Benjamin F. Miller et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mitophagy: A Complex Mechanism of Mitochondrial Removal

(2011) Ivana Novak   ANTIOXIDANTS & REDOX SIGNALING

Repeated resveratrol administration confers lasting protection against neuronal damage but induces dose-related alterations of behavioral impairments after global ischemia

(2011) Catrinel Girbovan et al.   BEHAVIOURAL PHARMACOLOGY

The regulation of mitochondrial morphology: Intricate mechanisms and dynamic machinery

(2011) Catherine S. Palmer et al.   CELLULAR SIGNALLING

The role of sirtuins in modulating redox stressors

(2011) Bradley R. Webster et al.   FREE RADICAL BIOLOGY AND MEDICINE

Omega-3 polyunsaturated fatty acids in the brain: metabolism and neuroprotection

(2011) Wenting Zhang   Frontiers in Bioscience-Landmark

Exercise training increases mitochondrial biogenesis in the brain

(2011) Jennifer L. Steiner et al.   JOURNAL OF APPLIED PHYSIOLOGY

Heme Oxygenase-1 Couples Activation of Mitochondrial Biogenesis to Anti-inflammatory Cytokine Expression

(2011) Claude A. Piantadosi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Making heads or tails of phospholipids in mitochondria

(2011) Christof Osman et al.   JOURNAL OF CELL BIOLOGY

Endoplasmic reticulum-specific BH3-only protein BNIP1 induces mitochondrial fragmentation in a Bcl-2- and Drp1-dependent manner

(2011) Seung-Wook Ryu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Crosstalk between mitochondrial (dys)function and mitochondrial abundance

(2011) Sébastien Michel et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking

(2011) Cathrin Meissner et al.   JOURNAL OF NEUROCHEMISTRY

Participation of MCP-induced protein 1 in lipopolysaccharide preconditioning-induced ischemic stroke tolerance by regulating the expression of proinflammatory cytokines

(2011) Jian Liang et al.   Journal of Neuroinflammation

Expression of Key Regulators of Mitochondrial Biogenesis in Growth Hormone Receptor Knockout (GHRKO) Mice is Enhanced but is Not Further Improved by Other Potential Life-Extending Interventions

(2011) A. Gesing et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

A Unified Model of Mammalian BCL-2 Protein Family Interactions at the Mitochondria

(2011) Fabien Llambi et al.   MOLECULAR CELL

Generation and characterization of transgenic mice expressing mitochondrial targeted red fluorescent protein selectively in neurons: modeling mitochondriopathy in excitotoxicity and amyotrophic lateral sclerosis

(2011) Yi Wang et al.   Molecular Neurodegeneration

Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity

(2011) Wenjun Song et al.   NATURE MEDICINE

MFN2 mutations cause severe phenotypes in most patients with CMT2A

(2011) S. M. E. Feely et al.   NEUROLOGY

Impact of exercise on mitochondrial transcription factor expression and damage in the striatum of a chronic mouse model of Parkinson's disease

(2011) Gaurav Patki et al.   NEUROSCIENCE LETTERS

Preconditioning Involves Selective Mitophagy Mediated by Parkin and p62/SQSTM1

(2011) Chengqun Huang et al.   PLoS One

Protective effects and mechanisms of sirtuins in the nervous system

(2011) Feng Zhang et al.   PROGRESS IN NEUROBIOLOGY

A new vicious cycle involving glutamate excitotoxicity, oxidative stress and mitochondrial dynamics

(2011) D Nguyen et al.   Cell Death & Disease

A high-throughput respirometric assay for mitochondrial biogenesis and toxicity

(2010) Craig C. Beeson et al.   ANALYTICAL BIOCHEMISTRY

Dynamic regulation of mitochondrial fission through modification of the dynamin-related protein Drp1

(2010) Chuang-Rung Chang et al.   Annals of the New York Academy of Sciences

Mitophagy Selectively Degrades Individual Damaged Mitochondria After Photoirradiation

(2010) Insil Kim et al.   ANTIOXIDANTS & REDOX SIGNALING

Reticulocyte mitophagy: Monitoring mitochondrial clearance in a mammalian model

(2010) Ji Zhang et al.   Autophagy

Mitophagy and Parkinson's disease: The PINK1–parkin link

(2010) Emma Deas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

(2010) Seok Min Jin et al.   JOURNAL OF CELL BIOLOGY

Co-regulation of nuclear respiratory factor-1 by NF B and CREB links LPS-induced inflammation to mitochondrial biogenesis

(2010) H. B. Suliman et al.   JOURNAL OF CELL SCIENCE

Upregulation of human selenoprotein H in murine hippocampal neuronal cells promotes mitochondrial biogenesis and functional performance

(2010) Natalia Mendelev et al.   MITOCHONDRION

Integrating multiple aspects of mitochondrial dynamics in neurons: Age-related differences and dynamic changes in a chronic rotenone model

(2010) Beth Arnold et al.   NEUROBIOLOGY OF DISEASE

Overexpression of mitochondrial transcription factor A (TFAM) ameliorates delayed neuronal death due to transient forebrain ischemia in mice

(2010) Masaaki Hokari et al.   NEUROPATHOLOGY

Reduced Basal Autophagy and Impaired Mitochondrial Dynamics Due to Loss of Parkinson's Disease-Associated Protein DJ-1

(2010) Guido Krebiehl et al.   PLoS One

Organellar vs cellular control of mitochondrial dynamics

(2010) Brigham B. Hyde et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Omega-3 Polyunsaturated Fatty Acid Supplementation Confers Long-Term Neuroprotection Against Neonatal Hypoxic–Ischemic Brain Injury Through Anti-Inflammatory Actions

(2010) Wenting Zhang et al.   STROKE

Transcriptional Control of Mitochondrial Biogenesis and Function

(2009) M. Benjamin Hock et al.   Annual Review of Physiology

Bid mediates fission, membrane permeabilization and peri-nuclear accumulation of mitochondria as a prerequisite for oxidative neuronal cell death

(2009) Julia Grohm et al.   BRAIN BEHAVIOR AND IMMUNITY

Role of BNIP3 and NIX in cell death, autophagy and mitophagy

(2009) J Zhang et al.   CELL DEATH AND DIFFERENTIATION

Nix is a selective autophagy receptor for mitochondrial clearance

(2009) Ivana Novak et al.   EMBO REPORTS

Mutant SOD1 in neuronal mitochondria causes toxicity and mitochondrial dynamics abnormalities

(2009) J. Magrane et al.   HUMAN MOLECULAR GENETICS

Mitochondrial membrane biogenesis: phospholipids and proteins go hand in hand: Figure 1.

(2009) Vishal M. Gohil et al.   JOURNAL OF CELL BIOLOGY

Ultrastructural mitochondrial modifications characteristic of mitofusin 2 mutations (CMT2A)

(2009) Guilhem Sole et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Mitofusins and OPA1 Mediate Sequential Steps in Mitochondrial Membrane Fusion

(2009) Zhiyin Song et al.   MOLECULAR BIOLOGY OF THE CELL

Resveratrol pretreatment protects rat brain from cerebral ischemic damage via a sirtuin 1–uncoupling protein 2 pathway

(2009) D. Della-Morte et al.   NEUROSCIENCE

Disruption of Mitochondrial DNA Replication in Drosophila Increases Mitochondrial Fast Axonal Transport In Vivo

(2009) Rehan M. Baqri et al.   PLoS One

Robust Docosahexaenoic Acid–Mediated Neuroprotection in a Rat Model of Transient, Focal Cerebral Ischemia

(2009) Ludmila Belayev et al.   STROKE

Heme Oxygenase-1 Regulates Cardiac Mitochondrial Biogenesis via Nrf2-Mediated Transcriptional Control of Nuclear Respiratory Factor-1

(2008) Claude A. Piantadosi et al.   CIRCULATION RESEARCH

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL

Effects of overexpression of Huntingtin proteins on mitochondrial integrity

(2008) Hongmin Wang et al.   HUMAN MOLECULAR GENETICS

The translocator maintenance protein Tam41 is required for mitochondrial cardiolipin biosynthesis

(2008) Stephan Kutik et al.   JOURNAL OF CELL BIOLOGY

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Characterization of OPA1 isoforms isolated from mouse tissues

(2008) Vasudheva Reddy Akepati et al.   JOURNAL OF NEUROCHEMISTRY

N-Terminal Mutant Huntingtin Associates with Mitochondria and Impairs Mitochondrial Trafficking

(2008) A. L. Orr et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial Membrane Potential in Axons Increases with Local Nerve Growth Factor or Semaphorin Signaling

(2008) J. Verburg et al.   JOURNAL OF NEUROSCIENCE

Assessing mitochondrial morphology and dynamics using fluorescence wide-field microscopy and 3D image processing

(2008) Wenjun Song et al.   METHODS

Assessing mitochondria biogenesis

(2008) Denis M. Medeiros   METHODS

Bax- or Bak-Induced Mitochondrial Fission Can Be Uncoupled from Cytochrome c Release

(2008) Clare Sheridan et al.   MOLECULAR CELL

Essential role for Nix in autophagic maturation of erythroid cells

(2008) Hector Sandoval et al.   NATURE

Rapidly Increased Neuronal Mitochondrial Biogenesis After Hypoxic-Ischemic Brain Injury

(2008) Wei Yin et al.   STROKE