PHLPP1 Gene Deletion Protects the Brain from Ischemic Injury

Mislocalization of the E3 Ligase, β-Transducin Repeat-containing Protein 1 (β-TrCP1), in Glioblastoma Uncouples Negative Feedback between the Pleckstrin Homology Domain Leucine-rich Repeat Protein Phosphatase 1 (PHLPP1) and Akt

(2011) Noel A. Warfel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pleckstrin Homology Domain Leucine-rich Repeat Protein Phosphatase (PHLPP): A New Player in Cell Signaling

(2011) Noel A. Warfel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Middle Cerebral Artery Occlusion Model in Rodents: Methods and Potential Pitfalls

(2011) Fudong Liu et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

PHLPP-1 Negatively Regulates Akt Activity and Survival in the Heart

(2010) Shigeki Miyamoto et al.   CIRCULATION RESEARCH

PHLPP1 splice variants differentially regulate AKT and PKCα signaling in hippocampal neurons: characterization of PHLPP proteins in the adult hippocampus

(2010) Travis C. Jackson et al.   JOURNAL OF NEUROCHEMISTRY

Protein phosphatase PHLPP1 controls the light-induced resetting of the circadian clock

(2010) S. Masubuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thrombin Mediates Severe Neurovascular Injury During Ischemia

(2010) Bo Chen et al.   STROKE

Protein phosphatase 2A PR130/B″α1 subunit binds to the SH2 domain-containing inositol polyphosphate 5-phosphatase 2 and prevents epidermal growth factor (EGF)-induced EGF receptor degradation sustaining EGF-mediated signaling

(2009) Karen Zwaenepoel et al.   FASEB JOURNAL

The neurovascular unit in the setting of stroke

(2009) G. J. del Zoppo   JOURNAL OF INTERNAL MEDICINE

The endogenous inhibitor of Akt, CTMP, is critical to ischemia-induced neuronal death

(2009) Takahiro Miyawaki et al.   NATURE NEUROSCIENCE

Severe Blood–Brain Barrier Disruption and Surrounding Tissue Injury

(2009) Bo Chen et al.   STROKE

The life of a cell: apoptosis regulation by the PI3K/PKB pathway

(2008) Vincent Duronio   BIOCHEMICAL JOURNAL

The Role of Akt Signaling in Oxidative Stress Mediates NF-κB Activation in Mild Transient Focal Cerebral Ischemia

(2008) Yun Seon Song et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Akt1 gene deletion and stroke

(2008) Jun Li et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

The Neurovascular Unit in Health and Disease: Introduction

(2008) E. H. Lo et al.   STROKE

PHLiPPing the switch on Akt and protein kinase C signaling

(2008) John Brognard et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM