Glycyrrhizin inactivates toll-like receptor (TLR) signaling pathway to reduce lipopolysaccharide-induced acute lung injury by inhibiting TLR2

Inhibition of myocardial hypertrophy by magnesium isoglycyrrhizinate through the TLR4/NF-κB signaling pathway in mice

(2018) Donglai Ma et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The protective effect of dexmedetomidine on LPS-induced acute lung injury through the HMGB1-mediated TLR4/NF-κB and PI3K/Akt/mTOR pathways

(2018) Lu Meng et al.   MOLECULAR IMMUNOLOGY

Activation of the TLR2-mediated downstream signaling pathways NF-κB and MAPK is responsible for B7-H3-augmented inflammatory response during S. pneumoniae infection

(2017) Xuqin Chen et al.   JOURNAL OF NEUROIMMUNOLOGY

Neutrophil transfer of miR-223 to lung epithelial cells dampens acute lung injury in mice

(2017) Viola Neudecker et al.   Science Translational Medicine

Glycyrrhizin, a Direct HMGB1 Antagonist, Ameliorates Inflammatory Infiltration in a Model of Autoimmune Thyroiditis via Inhibition of TLR2-HMGB1 Signaling

(2017) Chenyan Li et al.   THYROID

Glycyrrhizin Ameliorate Ischemia Reperfusion Lung Injury through Downregulate TLR2 Signaling Cascade in Alveolar Macrophages

(2017) Lin Fei et al.   Frontiers in Pharmacology

HMGB1 facilitates hypoxia-induced vWF upregulation through TLR2-MYD88-SP1 pathway

(2016) Bandana Singh et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Glycyrrhizic acid pretreatment prevents sepsis-induced acute kidney injury via suppressing inflammation, apoptosis and oxidative stress

(2016) Hongyu Zhao et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ulinastatin post-treatment attenuates lipopolysaccharide-induced acute lung injury in rats and human alveolar epithelial cells

(2016) Yunpeng Luo et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Knockdown of versican V1 induces a severe inflammatory response in LPS-induced acute lung injury via the TLR2-NF-κB signaling pathway in C57BL/6J mice

(2016) LULU XU et al.   Molecular Medicine Reports

Penehyclidine ameliorates acute lung injury by inhibiting Toll-like receptor 2/4 expression and nuclear factor-κB activation

(2016) NA WANG et al.   Experimental and Therapeutic Medicine

Esculin Inhibits the Inflammation of LPS-Induced Acute Lung Injury in Mice Via Regulation of TLR/NF-κB Pathways

(2015) Zhang Tianzhu et al.   INFLAMMATION

Glycyrrhizic Acid Prevents Sepsis-Induced Acute Lung Injury and Mortality in Rats

(2015) Hongyu Zhao et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Effects of acteoside on lipopolysaccharide-induced inflammation in acute lung injury via regulation of NF-κB pathway in vivo and in vitro

(2015) Wang Jing et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Glycyrrhizic acid inhibits apoptosis and fibrosis in carbon-tetrachloride-induced rat liver injury

(2015) Bo Liang   WORLD JOURNAL OF GASTROENTEROLOGY

Candesartan and glycyrrhizin ameliorate ischemic brain damage through downregulation of the TLR signaling cascade

(2014) Waleed Barakat et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Effect of Mild Hypothermia on the Expression of Toll-like Receptor 2 in Lung Tissues with Experimental Acute Lung Injury

(2014) Zhan-hong Tang et al.   Heart Lung and Circulation

Protective Effect of Curcumin on Acute Airway Inflammation of Allergic Asthma in Mice Through Notch1–GATA3 Signaling Pathway

(2014) Lei Chong et al.   INFLAMMATION

Wnt3a mitigates acute lung injury by reducing P2X7 receptor-mediated alveolar epithelial type I cell death

(2014) Y Guo et al.   Cell Death & Disease

Glycyrrhizin Attenuates Toll Like Receptor-2, -4 and Experimental Vasospasm in a Rat Model

(2014) Chih-Zen Chang et al.   Journal of Immunology Research

Cardioprotective Effects of Glycyrrhizic Acid Against Isoproterenol-Induced Myocardial Ischemia in Rats

(2011) Nagaraja Haleagrahara et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Alleviation of lung injury by glycyrrhizic acid in benzo(a)pyrene exposed rats: Probable role of soluble epoxide hydrolase and thioredoxin reductase

(2011) Wajhul Qamar et al.   TOXICOLOGY

Glycyrrhizin Treatment Is Associated with Attenuation of Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting Cyclooxygenase-2 and Inducible Nitric Oxide Synthase Expression

(2010) Yun-Feng Ni et al.   JOURNAL OF SURGICAL RESEARCH

Glycyrrhizin, the main active compound in liquorice, attenuates pro-inflammatory responses by interfering with membrane-dependent receptor signalling

(2009) Bärbel Schröfelbauer et al.   BIOCHEMICAL JOURNAL

Glycyrrhizin attenuates the development of carrageenan-induced lung injury in mice

(2008) M MENEGAZZI et al.   PHARMACOLOGICAL RESEARCH