Activation of peroxisome proliferation-activated receptor-γ inhibits transforming growth factor-β1-induced airway smooth muscle cell proliferation by suppressing Smad-miR-21 signaling

Transforming Growth Factor-β Receptors and Smads: Regulatory Complexity and Functional Versatility

(2017) Erine H. Budi et al.   TRENDS IN CELL BIOLOGY

Activation of AMPK α2 inhibits airway smooth muscle cells proliferation

(2016) Lu Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Activation of PPAR-γ inhibits PDGF-induced proliferation of mouse renal fibroblasts

(2016) Jiamei Lu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Cytosolic phospholipase A2α regulates G1 progression through modulating FOXO1 activity

(2016) Said Movahedi Naini et al.   FASEB JOURNAL

PRL-3 promotes the peritoneal metastasis of gastric cancer through the PI3K/Akt signaling pathway by regulating PTEN

(2016) Jianbo Xiong et al.   ONCOLOGY REPORTS

BMP-7 Attenuates TGF-β1-Induced Fibronectin Secretion and Apoptosis of NRK-52E Cells by the Suppression of miRNA-21

(2016) Zhong Yu et al.   ONCOLOGY RESEARCH

High intensity focused ultrasound inhibits melanoma cell migration and metastasis through attenuating microRNA-21-mediated PTEN suppression

(2016) Huan Li et al.   Oncotarget

The PPARγ agonist, rosiglitazone, attenuates airway inflammation and remodeling via heme oxygenase-1 in murine model of asthma

(2015) Jing Xu et al.   ACTA PHARMACOLOGICA SINICA

p-SMAD2/3 and DICER promote pre-miR-21 processing during pressure overload-associated myocardial remodeling

(2015) Raquel García et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Activation of peroxisome proliferator-activated receptor-γ (PPARγ) inhibits hepatoma cell growth via downregulation of SEPT2 expression

(2015) Liang-qi Cao et al.   CANCER LETTERS

microRNA-21 Regulates Cell Proliferation and Migration and Cross Talk with PTEN and p53 in Bladder Cancer

(2015) Mingde Lei et al.   DNA AND CELL BIOLOGY

Triptolide inhibits TGF-β1-induced cell proliferation in rat airway smooth muscle cells by suppressing Smad signaling

(2015) Ming Chen et al.   EXPERIMENTAL CELL RESEARCH

MiR-21 modulates human airway smooth muscle cell proliferation and migration in asthma through regulation of PTEN expression

(2015) Yun Liu et al.   EXPERIMENTAL LUNG RESEARCH

Recombinant adeno-associated virus-mediated inhibition of microRNA-21 protects mice against the lethal schistosome infection by repressing both IL-13 and transforming growth factor beta 1 pathways

(2015) Xing He et al.   HEPATOLOGY

MiR-21: an environmental driver of malignant melanoma?

(2015) Bodo C Melnik   Journal of Translational Medicine

Peroxisome proliferator-activated receptor γ attenuates serotonin-induced pulmonary artery smooth muscle cell proliferation and apoptosis inhibition involving ERK1/2 pathway

(2015) Xinyuan Han et al.   MICROVASCULAR RESEARCH

Inhibitory effects of peroxisome proliferator-activated receptor γ agonists on collagen IV production in podocytes

(2015) Yanjiao Li et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Caffeic Acid Inhibits UVB-induced Inflammation and Photocarcinogenesis Through Activation of Peroxisome Proliferator-activated Receptor-γin Mouse Skin

(2015) Agilan Balupillai et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

PPARγ Ligands Attenuate Hypoxia-Induced Proliferation in Human Pulmonary Artery Smooth Muscle Cells through Modulation of MicroRNA-21

(2015) David E. Green et al.   PLoS One

MicroRNA-21 plays an oncogenic role by targeting FOXO1 and activating the PI3K/AKT pathway in diffuse large B-cell lymphoma

(2015) Heounjeong Go et al.   Oncotarget

Rosiglitzone Suppresses Angiotensin II-Induced Production of KLF5 and Cell Proliferation in Rat Vascular Smooth Muscle Cells

(2015) Dengfeng Gao et al.   PLoS One

Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer

(2014) Claudia Fumarola et al.   BIOCHEMICAL PHARMACOLOGY

Activation of PPAR-γ ameliorates pulmonary arterial hypertension via inducing heme oxygenase-1 and p21WAF1: An in vivo study in rats

(2014) Dexin Zhang et al.   LIFE SCIENCES

The effect of FoxO1 on the proliferation of rat mesangial cells under high glucose conditions

(2014) F. Liu et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Posttranslational regulation of phosphatase and tensin homolog (PTEN) and its functional impact on cancer behaviors

(2014) Wenting Xu et al.   Drug Design Development and Therapy

Airway smooth muscle in airway reactivity and remodeling: what have we learned?

(2013) Y. S. Prakash   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

6-Shogaol inhibits breast and colon cancer cell proliferation through activation of peroxisomal proliferator activated receptor γ (PPARγ)

(2013) Boon Shing Tan et al.   CANCER LETTERS

Asiatic Acid Isolated From Centella Asiatica Inhibits TGF-β1-induced Collagen Expression in Human Keloid Fibroblasts via PPAR-γ Activation

(2013) Difei Bian et al.   International Journal of Biological Sciences

Metformin reduces airway inflammation and remodeling via activation of AMP-activated protein kinase

(2012) Chan Sun Park et al.   BIOCHEMICAL PHARMACOLOGY

Role of Forkhead Transcription Factors in Diabetes-Induced Oxidative Stress

(2012) Bhaskar Ponugoti et al.   Experimental Diabetes Research

Smad-mediated regulation of microRNA biosynthesis

(2012) Matthew T. Blahna et al.   FEBS LETTERS

FoxO transcription factors; Regulation by AKT and 14-3-3 proteins

(2011) Guri Tzivion et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Remodeling in asthma

(2011) Saleh Al-Muhsen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The emerging role of microRNAs in asthma

(2011) Xiaoying Jiang   MOLECULAR AND CELLULAR BIOCHEMISTRY

MicroRNA-21 targets tumor suppressor genes ANP32A and SMARCA4

(2011) K Schramedei et al.   ONCOGENE

The Nuclear Hormone Receptor PPARγas a Therapeutic Target in Major Diseases

(2011) Martina Victoria Schmidt et al.   TheScientificWorldJOURNAL

Proteasomal inhibition after injury prevents fibrosis by modulating TGF-β1signalling

(2011) Gökhan M Mutlu et al.   THORAX

Regulation of TGF-β signalling by protein phosphatases

(2010) Ting Liu et al.   BIOCHEMICAL JOURNAL

Anti-inflammatory Agents: Present and Future

(2010) Charles A. Dinarello   CELL

MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC)

(2010) Ji-guang Zhang et al.   CLINICA CHIMICA ACTA

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

(2010) Gang Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The widespread regulation of microRNA biogenesis, function and decay

(2010) Jacek Krol et al.   NATURE REVIEWS GENETICS

Regulation of TGF-  signaling by Smad7

(2009) X. Yan et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

MicroRNA-21 Is Up-Regulated in Allergic Airway Inflammation and Regulates IL-12p35 Expression

(2009) T. X. Lu et al.   JOURNAL OF IMMUNOLOGY

Structure and physiological functions of the human peroxisome proliferator-activated receptor γ

(2008) Andrzej Zieleniak et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

SMAD proteins control DROSHA-mediated microRNA maturation

(2008) Brandi N. Davis et al.   NATURE

PPAR-γ agonists inhibit profibrotic phenotypes in human lung fibroblasts and bleomycin-induced pulmonary fibrosis

(2007) Jami E. Milam et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY