Regulation of Plasticity and Fibrogenic Activity of Trabecular Meshwork Cells by Rho GTPase Signaling

Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis

(2013) Yong Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis

(2013) Valerie S LeBleu et al.   NATURE MEDICINE

Connective Tissue Growth Factor Causes Glaucoma by Modifying the Actin Cytoskeleton of the Trabecular Meshwork

(2012) Benjamin Junglas et al.   AMERICAN JOURNAL OF PATHOLOGY

Cellular Mechanisms of Tissue Fibrosis. 1. Common and organ-specific mechanisms associated with tissue fibrosis

(2012) Michael Zeisberg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Interplay between β1-Integrin and Rho Signaling Regulates Differential Scattering and Motility of Pancreatic Cancer Cells by Snail and Slug Proteins

(2012) Mario A. Shields et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autotaxin-Lysophosphatidic Acid Axis Is a Novel Molecular Target for Lowering Intraocular Pressure

(2012) Padma Iyer et al.   PLoS One

MicroRNA-21 Promotes Fibrosis of the Kidney by Silencing Metabolic Pathways

(2012) B. N. Chau et al.   Science Translational Medicine

The Actin–MRTF–SRF Gene Regulatory Axis and Myofibroblast Differentiation

(2012) Eric M. Small   Journal of Cardiovascular Translational Research

Transforming Growth Factor-β–Induced Endothelial-to-Mesenchymal Transition Is Partly Mediated by MicroRNA-21

(2011) Regalla Kumarswamy et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Transforming growth factor-β2 promotes Snail-mediated endothelial–mesenchymal transition through convergence of Smad-dependent and Smad-independent signalling

(2011) Damian Medici et al.   BIOCHEMICAL JOURNAL

The effect of biophysical attributes of the ocular trabecular meshwork associated with glaucoma on the cell response to therapeutic agents

(2011) Clayton T. McKee et al.   BIOMATERIALS

The role of TGF-β in the pathogenesis of primary open-angle glaucoma

(2011) Rudolf Fuchshofer et al.   CELL AND TISSUE RESEARCH

Pirfenidone

(2011) Natalie J. Carter   DRUGS

TGF-β-induced mesenchymal transition of MS-1 endothelial cells requires Smad-dependent cooperative activation of Rho signals and MRTF-A

(2011) Hajime Mihira et al.   JOURNAL OF BIOCHEMISTRY

MicroRNAs in idiopathic pulmonary fibrosis

(2011) Kusum V. Pandit et al.   Translational Research

miR-29 Is a Major Regulator of Genes Associated with Pulmonary Fibrosis

(2010) Leah Cushing et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Myocardin-Related Transcription Factor-A Controls Myofibroblast Activation and Fibrosis in Response to Myocardial Infarction

(2010) Eric M. Small et al.   CIRCULATION RESEARCH

Lmx1b is required for murine trabecular meshwork formation and for maintenance of corneal transparency

(2010) Pu Liu et al.   DEVELOPMENTAL DYNAMICS

Linking actin dynamics and gene transcription to drive cellular motile functions

(2010) Eric N. Olson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanistic basis of Rho GTPase-induced extracellular matrix synthesis in trabecular meshwork cells

(2009) Padmanabhan P. Pattabiraman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Role of the epithelial-mesenchymal transition regulator Slug in primary human cancers

(2009) Catarina Castro Alves   Frontiers in Bioscience-Landmark

Mechanically induced osteogenic differentiation - the role of RhoA, ROCKII and cytoskeletal dynamics

(2009) E. J. Arnsdorf et al.   JOURNAL OF CELL SCIENCE

Biomarkers for epithelial-mesenchymal transitions

(2009) Michael Zeisberg et al.   JOURNAL OF CLINICAL INVESTIGATION

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis

(2009) Souhila Medjkane et al.   NATURE CELL BIOLOGY

Primary Open-Angle Glaucoma

(2009) Young H. Kwon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Novel molecular insights into RhoA GTPase-induced resistance to aqueous humor outflow through the trabecular meshwork

(2008) Min Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Rho-kinase and myosin II affect dynamic neural crest cell behaviors during epithelial to mesenchymal transition in vivo

(2008) Jason D. Berndt et al.   DEVELOPMENTAL BIOLOGY

Extracellular matrix turnover and outflow resistance

(2008) Kate E. Keller et al.   EXPERIMENTAL EYE RESEARCH

Structural changes of the trabecular meshwork in different kinds of glaucoma

(2008) Ozan-Yüksel Tektas et al.   EXPERIMENTAL EYE RESEARCH

Snail is required for TGF -induced endothelial-mesenchymal transition of embryonic stem cell-derived endothelial cells

(2008) T. Kokudo et al.   JOURNAL OF CELL SCIENCE

Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis

(2008) E. van Rooij et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA