An integrated understanding of the physiological response to elevated extracellular phosphate

1,25-Dihydroxyvitamin D3 and extracellular inorganic phosphate activate mitogen-activated protein kinase pathway through fibroblast growth factor 23 contributing to hypertrophy and mineralization in osteoarthritic chondrocytes

(2012) Timoklia Orfanidou et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Role of FGFs/FGFRs in skeletal development and bone regeneration

(2012) Xiaolan Du et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Skeletal secretion of FGF-23 regulates phosphate and vitamin D metabolism

(2012) L. Darryl Quarles   Nature Reviews Endocrinology

Roles of Major Facilitator Superfamily Transporters in Phosphate Response in Drosophila

(2012) Clemens Bergwitz et al.   PLoS One

Regulation of cell proliferation and cell density by the inorganic phosphate transporter PiT1

(2012) Kristina Byskov et al.   Cell Division

Angiogenesis in bone regeneration

(2011) Kurt D. Hankenson et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Normalization of the Vasculature for Treatment of Cancer and Other Diseases

(2011) Shom Goel et al.   PHYSIOLOGICAL REVIEWS

Signaling of extracellular inorganic phosphate up-regulates cyclin D1 expression in proliferating chondrocytes via the Na+/Pi cotransporter Pit-1 and Raf/MEK/ERK pathway

(2010) Masaaki Kimata et al.   BONE

Inorganic Phosphate Induces Mammalian Growth Plate Chondrocyte Apoptosis in a Mitochondrial Pathway Involving Nitric Oxide and JNK MAP Kinase

(2010) M. Zhong et al.   CALCIFIED TISSUE INTERNATIONAL

Elevated Phosphate Activates N-ras and Promotes Cell Transformation and Skin Tumorigenesis

(2010) C. E. Camalier et al.   Cancer Prevention Research

Inhibition of bone resorption by inorganic phosphate is mediated by both reduced osteoclast formation and decreased activity of mature osteoclasts

(2010) A. John Yates et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Both FGF23 and extracellular phosphate activate Raf/MEK/ERK pathway via FGF receptors in HEK293 cells

(2010) Miwa Yamazaki et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Biomineralization and matrix vesicles in biology and pathology

(2010) Ellis E. Golub   Seminars in Immunopathology

Seeking unique and common biological themes in multiple gene lists or datasets: pathway pattern extraction pipeline for pathway-level comparative analysis

(2009) Ming Yi et al.   BMC BIOINFORMATICS

Is lowering phosphate exposure the key to preventing arterial stiffening with age?

(2009) C J Ferro et al.   HEART

Identification of a Novel Function of PiT1 Critical for Cell Proliferation and Independent of Its Phosphate Transport Activity

(2009) Laurent Beck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The emerging role of phosphate in vascular calcification

(2009) Cecilia M. Giachelli   KIDNEY INTERNATIONAL

The FGF family: biology, pathophysiology and therapy

(2009) Andrew Beenken et al.   NATURE REVIEWS DRUG DISCOVERY

Foxc2 Transcription Factor: A Newly Described Regulator of Angiogenesis

(2009) Tsutomu Kume   TRENDS IN CARDIOVASCULAR MEDICINE

High dietary inorganic phosphate enhances cap-dependent protein translation, cell-cycle progression, and angiogenesis in the livers of young mice

(2008) Cheng-Xiong Xu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

High Dietary Inorganic Phosphate Increases Lung Tumorigenesis and Alters Akt Signaling

(2008) Hua Jin et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Phosphorus levels are associated with subclinical atherosclerosis in the general population

(2008) Stephen J. Onufrak et al.   ATHEROSCLEROSIS

Regulation of growth factor signaling by FRS2 family docking/scaffold adaptor proteins

(2008) Noriko Gotoh   CANCER SCIENCE

The Mechanism of Phosphorus as a Cardiovascular Risk Factor in CKD

(2008) S. Mathew et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Novel 2-phenylquinolin-7-yl-derived imidazo[1,5-a]pyrazines as potent insulin-like growth factor-I receptor (IGF-IR) inhibitors

(2007) Mark J. Mulvihill et al.   BIOORGANIC & MEDICINAL CHEMISTRY

High extracellular inorganic phosphate concentration inhibits RANK-RANKL signaling in osteoclast-like cells

(2007) Anaïs Mozar et al.   JOURNAL OF CELLULAR PHYSIOLOGY