Modulation of macrophage activation and programming in immunity

Kruppel-Like Factor 4 Is Essential for Inflammatory Monocyte Differentiation In Vivo

(2014) J. K. Alder et al.   JOURNAL OF IMMUNOLOGY

mTOR Regulates T-Cell Differentiation and Activation in Immunity and Autoimmunity

(2012) Yujing Bi et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Tacrolimus potently inhibits human osteoclastogenesis induced by IL-17 from human monocytes alone and suppresses human Th17 differentiation

(2012) Toru Yago et al.   CYTOKINE

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Blockade of interleukin-6 signaling inhibits the classic pathway and promotes an alternative pathway of macrophage activation after spinal cord injury in mice

(2012) Alexander Rodriguez Guerrero et al.   Journal of Neuroinflammation

Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine

(2012) Jeremiah R. McDole et al.   NATURE

Notch–RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization

(2012) Haixia Xu et al.   NATURE IMMUNOLOGY

An essential role for TH2-type responses in limiting acute tissue damage during experimental helminth infection

(2012) Fei Chen et al.   NATURE MEDICINE

Hematopoietic miR155 Deficiency Enhances Atherosclerosis and Decreases Plaque Stability in Hyperlipidemic Mice

(2012) Marjo M. P. C. Donners et al.   PLoS One

Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization

(2012) A. Arranz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited

(2011) Joris Deelen et al.   AGING CELL

Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology

(2011) O. M. Pello et al.   BLOOD

Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers

(2011) E. Sierra-Filardi et al.   BLOOD

Lack of Interleukin-1 Receptor I (IL-1RI) Protects Mice From High-Fat Diet-Induced Adipose Tissue Inflammation Coincident With Improved Glucose Homeostasis

(2011) F. C. McGillicuddy et al.   DIABETES

Alternative activation of macrophages by IL-4 requires SHIP degradation

(2011) Shelley B. Weisser et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulators of macrophage activation

(2011) Fernando O. Martinez   EUROPEAN JOURNAL OF IMMUNOLOGY

Macrophages participate in IL-17-mediated inflammation

(2011) Jobert G. Barin et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interferon regulatory factor 3 inhibits astrocyte inflammatory gene expression through suppression of the proinflammatory miR-155 and miR-155*

(2011) Leonid Tarassishin et al.   GLIA

A balance between tissue-destructive and tissue-protective immunities: A role of toll-like receptors in regulation of adaptive immunity

(2011) V.I. Seledtsov et al.   IMMUNOBIOLOGY

An instructive role of donor macrophages in mixed chimeras in the induction of recipient CD4+ Foxp3+ Treg cells

(2011) Guangwei Liu et al.   IMMUNOLOGY AND CELL BIOLOGY

Silencer of Death Domains (SODD) Inhibits Skeletal Muscle and Kidney Enriched Inositol 5-Phosphatase (SKIP) and Regulates Phosphoinositide 3-Kinase (PI3K)/Akt Signaling to the Actin Cytoskeleton

(2011) Parvin Rahman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Krüppel-like factor 4 regulates macrophage polarization

(2011) Xudong Liao et al.   JOURNAL OF CLINICAL INVESTIGATION

Endotoxin Tolerance Represents a Distinctive State of Alternative Polarization (M2) in Human Mononuclear Cells

(2011) O. M. Pena et al.   JOURNAL OF IMMUNOLOGY

Akt Induces Osteoclast Differentiation through Regulating the GSK3 /NFATc1 Signaling Cascade

(2011) J. B. Moon et al.   JOURNAL OF IMMUNOLOGY

IL-27 and IL-21 Are Associated with T Cell IL-10 Responses in Human Visceral Leishmaniasis

(2011) Nasim Akhtar Ansari et al.   JOURNAL OF IMMUNOLOGY

Macrophages at the Fetal-Maternal Interface Express Markers of Alternative Activation and Are Induced by M-CSF and IL-10

(2011) J. Svensson et al.   JOURNAL OF IMMUNOLOGY

Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function

(2011) Claire S. Whyte et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Obstacles and opportunities for understanding macrophage polarization

(2011) P. J. Murray et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Selenium Levels Affect the IL-4–Induced Expression of Alternative Activation Markers in Murine Macrophages

(2011) Shakira M. Nelson et al.   JOURNAL OF NUTRITION

IL-25 Induces M2 Macrophages and Reduces Renal Injury in Proteinuric Kidney Disease

(2011) Q. Cao et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

(2011) Thomas Krausgruber et al.   NATURE IMMUNOLOGY

Alternatively activated macrophages and impaired phagocytosis of S. aureus in chronic rhinosinusitis

(2010) O. Krysko et al.   ALLERGY

HIF1A Overexpression Is Associated with Poor Prognosis in a Cohort of 731 Colorectal Cancers

(2010) Yoshifumi Baba et al.   AMERICAN JOURNAL OF PATHOLOGY

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

Notch Signaling Determines the M1 versus M2 Polarization of Macrophages in Antitumor Immune Responses

(2010) Yao-Chun Wang et al.   CANCER RESEARCH

Interleukin-33 Induces Protective Effects in Adipose Tissue Inflammation During Obesity in Mice

(2010) Ashley M. Miller et al.   CIRCULATION RESEARCH

Characterization of ST2 transgenic mice with resistance to IL-33

(2010) Hiromi Ohto-Ozaki et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Differential activation and antagonistic function of HIF-  isoforms in macrophages are essential for NO homeostasis

(2010) N. Takeda et al.   GENES & DEVELOPMENT

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

STAT6 Transcription Factor Is a Facilitator of the Nuclear Receptor PPARγ-Regulated Gene Expression in Macrophages and Dendritic Cells

(2010) Attila Szanto et al.   IMMUNITY

Phenotypic and functional switch of macrophages induced by regulatory CD4+ CD25+ T cells in mice

(2010) Guangwei Liu et al.   IMMUNOLOGY AND CELL BIOLOGY

The Interleukin 13 (IL-13) Pathway in Human Macrophages Is Modulated by MicroRNA-155 via Direct Targeting of Interleukin 13 Receptor α1 (IL13Rα1)

(2010) Rocio T. Martinez-Nunez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SHIP Represses Th2 Skewing by Inhibiting IL-4 Production from Basophils

(2010) E. Kuroda et al.   JOURNAL OF IMMUNOLOGY

IL-27/IFN-  Induce MyD88-Dependent Steroid-Resistant Airway Hyperresponsiveness by Inhibiting Glucocorticoid Signaling in Macrophages

(2010) J. J. Li et al.   JOURNAL OF IMMUNOLOGY

The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

(2010) Takashi Satoh et al.   NATURE IMMUNOLOGY

PPARγ Controls Dectin-1 Expression Required for Host Antifungal Defense against Candida albicans

(2010) Amandine Galès et al.   PLoS Pathogens

Absence of Akt1 Reduces Vascular Smooth Muscle Cell Migration and Survival and Induces Features of Plaque Vulnerability and Cardiac Dysfunction During Atherosclerosis

(2009) Carlos Fernández-Hernando et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Epigenetic regulation of the alternatively activated macrophage phenotype

(2009) M. Ishii et al.   BLOOD

SHIP prevents lipopolysaccharide from triggering an antiviral response in mice

(2009) L. M. Sly et al.   BLOOD

PPAR γ is highly expressed in F4/80hi adipose tissue macrophages and dampens adipose-tissue inflammation

(2009) Josep Bassaganya-Riera et al.   CELLULAR IMMUNOLOGY

Alternative activation of macrophages: Immune function and cellular biology

(2009) Audrey Varin et al.   IMMUNOBIOLOGY

Alternatively activated macrophages in infection and autoimmunity

(2009) DeLisa Fairweather et al.   JOURNAL OF AUTOIMMUNITY

SHIP Represses the Generation of IL-3-Induced M2 Macrophages by Inhibiting IL-4 Production from Basophils

(2009) E. Kuroda et al.   JOURNAL OF IMMUNOLOGY

Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor  B

(2009) C. Porta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A CREB-C/EBP  cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair

(2009) D. Ruffell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative Activation of Macrophages: An Immunologic Functional Perspective

(2008) Fernando O. Martinez et al.   Annual Review of Immunology

Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System

(2008) Sherry L. LaPorte et al.   CELL

CC chemokine receptor 4 modulates Toll-like receptor 9-mediated innate immunity and signaling

(2008) Makoto Ishii et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Genome-wide profiling of PPAR :RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis

(2008) R. Nielsen et al.   GENES & DEVELOPMENT

Integrated Regulation of Toll-like Receptor Responses by Notch and Interferon-γ Pathways

(2008) Xiaoyu Hu et al.   IMMUNITY

The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance

(2008) Paola Allavena et al.   IMMUNOLOGICAL REVIEWS

Type I IL-4Rs Selectively Activate IRS-2 to Induce Target Gene Expression in Macrophages

(2008) N. M. Heller et al.   Science Signaling

Macrophage polarization in tumour progression

(2008) Antonio Sica et al.   SEMINARS IN CANCER BIOLOGY