Oxidases and reactive oxygen species during hematopoiesis: A focus on megakaryocytes

Lack of autophagy in the hematopoietic system leads to loss of hematopoietic stem cell function and dysregulated myeloid proliferation

(2011) Monika Mortensen et al.   Autophagy

Do reactive oxygen species play a role in myeloid leukemias?

(2011) P. S. Hole et al.   BLOOD

Regulatory effects of TLR2 on megakaryocytic cell function

(2011) L. M. Beaulieu et al.   BLOOD

Upregulation of Nox4 in the aging vasculature and its association with smooth muscle cell polyploidy

(2011) Donald McCrann et al.   CELL CYCLE

Autophagy in the pathogenesis of myelodysplastic syndrome and acute myeloid leukemia

(2011) Alexander Scarth Watson et al.   CELL CYCLE

Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche

(2011) Toshio Suda et al.   Cell Stem Cell

Reactive oxygen species: Are they important for haematopoiesis?

(2011) José L. Sardina et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Reactive oxygen species and hematopoietic stem cell senescence

(2011) Lijian Shao et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Control of Megakaryocyte Expansion and Bone Marrow Fibrosis by Lysyl Oxidase

(2011) Alexia Eliades et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NAD(P)H: Quinone Oxidoreductase 1 Deficiency Conjoint with Marginal Vitamin C Deficiency Causes Cigarette Smoke Induced Myelodysplastic Syndromes

(2011) Archita Das et al.   PLoS One

Tyr740and Tyr751residues of platelet-derived growth factor beta receptor are responsible for the redox regulation of phosphatase and tensin homolog in the cells stimulated with platelet-derived growth factor

(2011) Inyoung Kim et al.   REDOX REPORT

p22phox-dependent NADPH oxidase activity is required for megakaryocytic differentiation

(2010) J L Sardina et al.   CELL DEATH AND DIFFERENTIATION

Oxidative stress is increased in primary and post−polycythemia vera myelofibrosis

(2010) Claudia Vener et al.   EXPERIMENTAL HEMATOLOGY

New Roles for Cyclin E in Megakaryocytic Polyploidization

(2010) Alexia Eliades et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple roles of the cell cycle inhibitor p21CDKN1A in the DNA damage response

(2010) Ornella Cazzalini et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

The impact of redox and thiol status on the bone marrow: Pharmacological intervention strategies

(2010) Christina L. Grek et al.   PHARMACOLOGY & THERAPEUTICS

A Senescence-Like Cell-Cycle Arrest Occurs During Megakaryocytic Maturation: Implications for Physiological and Pathological Megakaryocytic Proliferation

(2010) Rodolphe Besancenot et al.   PLOS BIOLOGY

Autophagy is an important event for megakaryocytic differentiation of the chronic myelogenous leukemia K562 cell line

(2009) Pascal Colosetti et al.   Autophagy

NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation

(2009) H. Motohashi et al.   BLOOD

Differential expression of NADPH oxidases in megakaryocytes and their role in polyploidy

(2009) D. J. McCrann et al.   BLOOD

A Loss-of-Function Polymorphism in the Propeptide Domain of the LOX Gene and Breast Cancer

(2009) C. Min et al.   CANCER RESEARCH

Mitochondria and reactive oxygen species

(2009) Alicia J. Kowaltowski et al.   FREE RADICAL BIOLOGY AND MEDICINE

The hematopoietic stem cell niche: Low in oxygen but a nice place to be

(2009) Pernilla Eliasson et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The mitogen-activated protein kinase signaling pathways: role in megakaryocyte differentiation

(2009) S. SÉVERIN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Erythroid precursors from patients with low-risk myelodysplasia demonstrate ultrastructural features of enhanced autophagy of mitochondria

(2009) E J Houwerzijl et al.   LEUKEMIA

Bone Marrow Osteoblastic Niche: A New Model to Study Physiological Regulation of Megakaryopoiesis

(2009) Isabella Pallotta et al.   PLoS One

Oxidative Stress in the Regulation of Normal and Neoplastic Hematopoiesis

(2008) Saghi Ghaffari   ANTIOXIDANTS & REDOX SIGNALING

15-deoxy- 12,14-PGJ2 enhances platelet production from megakaryocytes

(2008) J. J. O'Brien et al.   BLOOD

Regulation of lysyl oxidase in vascular cells: lysyl oxidase as a new player in cardiovascular diseases

(2008) C. Rodriguez et al.   CARDIOVASCULAR RESEARCH

Lysyl Oxidase Oxidizes Cell Membrane Proteins and Enhances the Chemotactic Response of Vascular Smooth Muscle Cells

(2008) Héctor A. Lucero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY