Chrysophanol induces cell death and inhibits invasiveness via mitochondrial calcium overload in ovarian cancer cells

Chrysin attenuates progression of ovarian cancer cells by regulating signaling cascades and mitochondrial dysfunction

(2017) Whasun Lim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Affinity chromatographic methodologies based on immobilized voltage dependent anion channel isoform 1 and application in protein-ligand interaction analysis and bioactive compounds screening from traditional medicine

(2017) Qian Li et al.   JOURNAL OF CHROMATOGRAPHY A

Ovarian cancer recurrence and early detection: may HE4 play a key role in this open challenge? A systematic review of literature

(2017) Stella Capriglione et al.   MEDICAL ONCOLOGY

Emodin suppresses proliferation, migration and invasion in ovarian cancer cells by down regulating ILK in vitro and in vivo

(2017) Jingjing Lu et al.   OncoTargets and Therapy

The Regulation of Tumor Cell Invasion and Metastasis by Endoplasmic Reticulum-to-Mitochondrial Ca2+ Transfer

(2017) Carl White   Frontiers in Oncology

Chrysophanol Induces Apoptosis of Choriocarcinoma Through Regulation of ROS and the AKT and ERK1/2 Pathways

(2016) Whasun Lim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cellular and molecular processes in ovarian cancer metastasis. A Review in the Theme: Cell and Molecular Processes in Cancer Metastasis

(2015) Tsz-Lun Yeung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The mitochondrial voltage-dependent anion channel 1 in tumor cells

(2015) Varda Shoshan-Barmatz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Mitochondrial apoptosis: killing cancer using the enemy within

(2015) J Lopez et al.   BRITISH JOURNAL OF CANCER

Cinobufagin exerts anti-proliferative and pro-apoptotic effects through the modulation ROS-mediated MAPKs signaling pathway

(2015) Seung Ho Baek et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Anticancer drugs for the modulation of endoplasmic reticulum stress and oxidative stress

(2015) Ammad Ahmad Farooqi et al.   TUMOR BIOLOGY

Limitations to the use of carboplatin-based therapy in advanced ovarian cancer

(2015) Christina Fotopoulou   EJC SUPPLEMENTS

FOXO3-mediated up-regulation of Bim contributes to rhein-induced cancer cell apoptosis

(2014) Jiao Wang et al.   APOPTOSIS

Oxidative Stress and Antioxidants in Disease and Cancer: A Review

(2014) Rakesh Kumar Gupta et al.   Asian Pacific Journal of Cancer Prevention

Emodin-Provoked Oxidative Stress Induces Apoptosis in Human Colon Cancer HCT116 Cells through a p53-Mitochondrial Apoptotic Pathway

(2014) Mei-Juan Xie et al.   Asian Pacific Journal of Cancer Prevention

Ovarian cancer cell invasiveness is associated with discordant exosomal sequestration of Let-7 miRNA and miR-200

(2014) Miharu Kobayashi et al.   Journal of Translational Medicine

Treatment options in recurrent ovarian cancer: latest evidence and clinical potential

(2014) Daniela Luvero et al.   Therapeutic Advances in Medical Oncology

2-Aminophenoxazine-3-one-induced apoptosis via generation of reactive oxygen species followed by c-jun N-terminal kinase activation in the human glioblastoma cell line LN229

(2013) XIAO-FANG CHE et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

Chrysophanol-induced necrotic-like cell death through an impaired mitochondrial ATP synthesis in Hep3B human liver cancer cells

(2012) Chien-Hang Ni et al.   ARCHIVES OF PHARMACAL RESEARCH

Mitochondrial Ca2+ and apoptosis

(2012) Carlotta Giorgi et al.   CELL CALCIUM

Chrysophanol-induced cell death (necrosis) in human lung cancer A549 cells is mediated through increasing reactive oxygen species and decreasing the level of mitochondrial membrane potential

(2012) Chien-Hang Ni et al.   ENVIRONMENTAL TOXICOLOGY

Two Novel Naphthalene Glucosides and an Anthraquinone Isolated from Rumex dentatus and Their Antiproliferation Activities in Four Cell Lines

(2012) Hui Zhang et al.   MOLECULES

Oxidative stress caused by mitochondrial calcium overload

(2010) Tsung-I Peng et al.   Annals of the New York Academy of Sciences

Danthron, an Anthraquinone Derivative, Induces DNA Damage and Caspase Cascades-Mediated Apoptosis in SNU-1 Human Gastric Cancer Cells through Mitochondrial Permeability Transition Pores and Bax-Triggered Pathways

(2010) Jo-Hua Chiang et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Chrysophanol induces necrosis through the production of ROS and alteration of ATP levels in J5 human liver cancer cells

(2010) Chi-Cheng Lu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The Role of Mitochondria in Apoptosis

(2009) Chunxin Wang et al.   Annual Review of Genetics

Aloe-emodin induces apoptosis of human nasopharyngeal carcinoma cells via caspase-8-mediated activation of the mitochondrial death pathway

(2009) Meng-Liang Lin et al.   CANCER LETTERS

Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis

(2008) P Pinton et al.   ONCOGENE