FOXO3-mediated up-regulation of Bim contributes to rhein-induced cancer cell apoptosis

FOXO3a Is a Major Target of Inactivation by PI3K/AKT Signaling in Aggressive Neuroblastoma

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Endoplasmic reticulum stress in amelogenesis imperfecta and phenotypic rescue using 4-phenylbutyrate

(2013) Steven J. Brookes et al.   HUMAN MOLECULAR GENETICS

Vemurafenib Potently Induces Endoplasmic Reticulum Stress-Mediated Apoptosis in BRAFV600E Melanoma Cells

(2013) D. Beck et al.   Science Signaling

Fenofibrate-induced nuclear translocation of FoxO3A triggers Bim-mediated apoptosis in glioblastoma cells in vitro

(2012) Anna Wilk et al.   CELL CYCLE

Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis

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The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies

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CHOP Potentially Co-Operates with FOXO3a in Neuronal Cells to Regulate PUMA and BIM Expression in Response to ER Stress

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Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma

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Quantitative determination of rhein in human plasma by liquid chromatography–negative electrospray ionization tandem mass/mass spectrometry and the application in a pharmacokinetic study

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Roles of BIM induction and survivin downregulation in lapatinib-induced apoptosis in breast cancer cells with HER2 amplification

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New role of the BCL2 family of proteins in the regulation of mitochondrial dynamics

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Roles of GRP78 in physiology and cancer

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Akt is the downstream target of GRP78 in mediating cisplatin resistance in ER stress-tolerant human lung cancer cells

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Rhein Lysinate Suppresses the Growth of Tumor Cells and Increases the Anti-Tumor Activity of Taxol in Mice

(2009) Ya-Jun Lin et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Bcl-2 Inhibitors: Targeting Mitochondrial Apoptotic Pathways in Cancer Therapy

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Bim-targeted cancer therapy: A link between drug action and underlying molecular changes

(2009) T. Akiyama et al.   MOLECULAR CANCER THERAPEUTICS

Rhein lysinate suppresses the growth of breast cancer cells and potentiates the inhibitory effect of Taxol in athymic mice

(2008) Ya-Jun Lin et al.   ANTI-CANCER DRUGS

Inhibition of MEK blocks GRP78 up-regulation and enhances apoptosis induced by ER stress in gastric cancer cells

(2008) Lin Jie Zhang et al.   CANCER LETTERS

Sorafenib induces apoptosis of AML cells via Bim-mediated activation of the intrinsic apoptotic pathway

(2008) W Zhang et al.   LEUKEMIA

Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium

(2008) Y. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA