Sclerostin is expressed in osteoclasts from aged mice and reduces osteoclast-mediated stimulation of mineralization

Impairment of osteoblast differentiation due to proliferation-independent telomere dysfunction in mouse models of accelerated aging

(2012) Haitao Wang et al.   AGING CELL

Molecular Mechanisms in Coupling of Bone Formation to Resorption

(2012) T. John Martin et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Demonstration of osteocytic perilacunar/canalicular remodeling in mice during lactation

(2012) Hai Qing et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Age-related changes in gap junctional intercellular communication in osteoblastic cells

(2012) Damian C. Genetos et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells

(2012) Lingling Xian et al.   NATURE MEDICINE

Examination of nuclear receptor expression in osteoblasts reveals rorβ as an important regulator of osteogenesis

(2011) Matthew M Roforth et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osteoporosis: now and the future

(2011) Tilman D Rachner et al.   LANCET

Distinct Modes of Inhibition by Sclerostin on Bone Morphogenetic Protein and Wnt Signaling Pathways

(2010) Carola Krause et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of chronic estrogen treatment on modulating age-related bone loss in female mice

(2010) Farhan A Syed et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody

(2010) Desmond Padhi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Relation of age, gender, and bone mass to circulating sclerostin levels in women and men

(2010) Ulrike I Mödder et al.   JOURNAL OF BONE AND MINERAL RESEARCH

TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation

(2009) Yi Tang et al.   NATURE MEDICINE

Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone Strength

(2008) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength in a Rat Model of Postmenopausal Osteoporosis*

(2008) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Building bone to reverse osteoporosis and repair fractures

(2008) Sundeep Khosla et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate

(2008) L. Pederson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA