Distinct Modes of Inhibition by Sclerostin on Bone Morphogenetic Protein and Wnt Signaling Pathways

The syndromic status of sclerosteosis and van Buchem disease

(2010) P. Beighton et al.   CLINICAL GENETICS

Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength

(2010) Michael S Ominsky et al.   JOURNAL OF BONE AND MINERAL RESEARCH

NMR structure of the Wnt modulator protein Sclerostin

(2009) Stella E. Weidauer et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor α and disuse

(2009) Gul Zaman et al.   BONE

Characterization of the Structural Features and Interactions of Sclerostin

(2009) Vaclav Veverka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sclerostin Mediates Bone Response to Mechanical Unloading Through Antagonizing Wnt/β-Catenin Signaling

(2009) Chuwen Lin et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osteocytes, mechanosensing and Wnt signaling

(2008) Lynda F. Bonewald et al.   BONE

BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway

(2008) N. Kamiya et al.   DEVELOPMENT

The Association of GSK3β with E2F1 Facilitates Nerve Growth Factor-induced Neural Cell Differentiation

(2008) Fangfang Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osteocyte-Derived Sclerostin Inhibits Bone Formation: Its Role in Bone Morphogenetic Protein and Wnt Signaling

(2008) Peter ten Dijke et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength in a Rat Model of Postmenopausal Osteoporosis*

(2008) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The Ubiquitin-Proteasome System Is a Key Component of the SUMO-2/3 Cycle

(2008) Joost Schimmel et al.   MOLECULAR & CELLULAR PROTEOMICS

Control of Bone Mass and Remodeling by PTH Receptor Signaling in Osteocytes

(2008) Charles A. O'Brien et al.   PLoS One

Bone morphogenetic protein-7 protects human intervertebral disc cells in vitro from apoptosis

(2007) Aiqun Wei et al.   Spine Journal