The R740S mutation in the V-ATPase a3 subunit results in osteoclast apoptosis and defective early-stage autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

(2014) Daniel J. Klionsky et al.   Autophagy

Autophagy regulates TNFα-mediated joint destruction in experimental arthritis

(2012) Neng-Yu Lin et al.   ANNALS OF THE RHEUMATIC DISEASES

Inhibition of lysosome degradation on autophagosome formation and responses to GMI, an immunomodulatory protein fromGanoderma microsporum

(2012) I-Lun Hsin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Microtubule-associated protein light chain 3 regulates Cdc42-dependent actin ring formation in osteoclast

(2012) Yeon-Ho Chung et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

V-ATPase subunit ATP6AP1 (Ac45) regulates osteoclast differentiation, extracellular acidification, lysosomal trafficking, and protease exocytosis in osteoclast-mediated bone resorption

(2012) De-Qin Yang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The R740S mutation in the V-ATPase a3 subunit increases lysosomal pH, impairs NFATc1 translocation, and decreases in vitro osteoclastogenesis

(2012) Irina Voronov et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Autophagy Proteins Regulate the Secretory Component of Osteoclastic Bone Resorption

(2011) Carl J. DeSelm et al.   DEVELOPMENTAL CELL

The V-ATPase a3 subunit mutation R740S is dominant negative and results in osteopetrosis in mice

(2011) Noelle Ochotny et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Versatile Roles of V-ATPases Accessory Subunit Ac45 in Osteoclast Formation and Function

(2011) An Qin et al.   PLoS One

Regulation and Isoform Function of the V-ATPases

(2010) Masashi Toei et al.   BIOCHEMISTRY

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Severe developmental bone phenotype in ClC-7 deficient mice

(2010) A.V. Neutzsky-Wulff et al.   DEVELOPMENTAL BIOLOGY

Impaired gastric acidification negatively affects calcium homeostasis and bone mass

(2009) Thorsten Schinke et al.   NATURE MEDICINE