Prostaglandin E2promotesMYCNnon-amplified neuroblastoma cell survivalviaβ-catenin stabilization

The discovery and development of cyclooxygenase-2 inhibitors as potential anticancer therapies

(2014) Mohsen Vosooghi et al.   Expert Opinion on Drug Discovery

Protein kinase a-dependent pSer675 -β-catenin, a novel signaling defect in a mouse model of congenital hepatic fibrosis

(2013) Carlo Spirli et al.   HEPATOLOGY

XAV939, a tankyrase 1 inhibitior, promotes cell apoptosis in neuroblastoma cell lines by inhibiting Wnt/β-catenin signaling pathway

(2013) Xiao-Hong Tian et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Celecoxib Inhibits β-Catenin-Dependent Survival of the Human Osteosarcoma MG-63 Cell Line

(2013) J-J Xia et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Knockdown of β-catenin expression inhibits neuroblastoma cell growth in vitro and in vivo

(2013) Wei Yao et al.   JOURNAL OF PEDIATRIC SURGERY

Cell Survival Signalling through PPARδ and Arachidonic Acid Metabolites in Neuroblastoma

(2013) Emma Bell et al.   PLoS One

Celecoxib potentially inhibits metastasis of lung cancer promoted by surgery in mice, via suppression of the PGE2-modulated β-catenin pathway

(2013) Shuai Zhang et al.   TOXICOLOGY LETTERS

Neuroblastoma and MYCN

(2013) M. Huang et al.   Cold Spring Harbor Perspectives in Medicine

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

Activated β-catenin Forces N2A Cell-derived Neurons Back to Tumor-like Neuroblasts and Positively Correlates with a Risk for Human Neuroblastoma

(2012) Feng Zhi et al.   International Journal of Biological Sciences

N-myc and Noncoding RNAs in Neuroblastoma

(2012) J. Buechner et al.   MOLECULAR CANCER RESEARCH

Autocrine Prostaglandin E2 Signaling Promotes Tumor Cell Survival and Proliferation in Childhood Neuroblastoma

(2012) Agnes Rasmuson et al.   PLoS One

Cyclooxygenase-1, not cyclooxygenase-2, is responsible for physiological production of prostacyclin in the cardiovascular system

(2012) N. S. Kirkby et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt pathway activity confers chemoresistance to cancer stem-like cells in a neuroblastoma cell line

(2012) Sharada D. Vangipuram et al.   TUMOR BIOLOGY

Protein kinase A antagonist inhibits β-catenin nuclear translocation, c-Myc and COX-2 expression and tumor promotion in ApcMin/+ mice

(2011) Kristoffer W Brudvik et al.   Molecular Cancer

Wnt signaling and its downstream target N-myc regulate basal progenitors in the developing neocortex

(2010) A. Kuwahara et al.   DEVELOPMENT

Recent Advances in Neuroblastoma

(2010) John M. Maris   NEW ENGLAND JOURNAL OF MEDICINE

E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer

(2009) Otto Schmalhofer et al.   CANCER AND METASTASIS REVIEWS

Prolonged low-dose administration of the cyclooxygenase-2 inhibitor celecoxib enhances the antitumor activity of irinotecan against neuroblastoma xenografts

(2009) Michio Kaneko et al.   CANCER SCIENCE

The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment

(2009) A. Greenhough et al.   CARCINOGENESIS

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE

Cyclooxygenase-2 Inhibition Inhibits c-Met Kinase Activity and Wnt Activity in Colon Cancer

(2008) J. B. Tuynman et al.   CANCER RESEARCH

Virodhamine and CP55,940 modulate cAMP production and IL-8 release in human bronchial epithelial cells

(2007) E Gkoumassi et al.   BRITISH JOURNAL OF PHARMACOLOGY