Poly (I:C) therapy decreases cerebral ischaemia/reperfusion injuryviaTLR3-mediated prevention of Fas/FADD interaction

25-Hydroxycholesterol suppresses interleukin-1-driven inflammation downstream of type I interferon

(2014) A. Reboldi et al.   SCIENCE

The TLR9 Ligand, CpG‐ODN, Induces Protection against Cerebral Ischemia/Reperfusion Injury via Activation of PI3K/Akt Signaling

(2014) Chen Lu et al.   Journal of the American Heart Association

Chloroquine pretreatment inhibits toll-like receptor 3 signaling after stroke

(2013) Guiyun Cui et al.   NEUROSCIENCE LETTERS

Toll-like receptor 3 agonist Poly I:C protects against simulated cerebral ischemia in vitro and in vivo

(2012) Lin-na Pan et al.   ACTA PHARMACOLOGICA SINICA

Poly-ICLC preconditioning protects the blood-brain barrier against ischemic injuryin vitrothrough type I interferon signaling

(2012) Raffaella Gesuete et al.   JOURNAL OF NEUROCHEMISTRY

Disruption of downstream MyD88 or TRIF Toll-like receptor signaling does not protect against cerebral ischemia

(2011) Bolanle M. Famakin et al.   BRAIN RESEARCH

Poly-IC Preconditioning Protects against Cerebral and Renal Ischemia-Reperfusion Injury

(2011) Amy E B Packard et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

TLR2 Ligand Induces Protection against Cerebral Ischemia/Reperfusion Injury via Activation of Phosphoinositide 3-Kinase/Akt Signaling

(2011) C. Lu et al.   JOURNAL OF IMMUNOLOGY

Caspase signalling controls microglia activation and neurotoxicity

(2011) Miguel A. Burguillos et al.   NATURE

Acute anti-inflammatory approaches to ischemic stroke

(2010) Gregory J. Del Zoppo   Annals of the New York Academy of Sciences

TLR2 ligands induce cardioprotection against ischaemia/reperfusion injury through a PI3K/Akt-dependent mechanism

(2010) T. Ha et al.   CARDIOVASCULAR RESEARCH

Scavenger Receptor Class-A Has a Central Role in Cerebral Ischemia–Reperfusion Injury

(2010) Chen Lu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Toll-like receptor 4 (TLR4), but not TLR3 or TLR9, knock-out mice have neuroprotective effects against focal cerebral ischemia

(2010) K. Hyakkoku et al.   NEUROSCIENCE

Microglial activation in stroke: Therapeutic targets

(2010) Midori A. Yenari et al.   Neurotherapeutics

The TRIF-dependent signaling pathway is not required for acute cerebral ischemia/reperfusion injury in mice

(2009) Fang Hua et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Differential roles of TLR2 and TLR4 in acute focal cerebral ischemia/reperfusion injury in mice

(2009) Fang Hua et al.   BRAIN RESEARCH

Heart Disease and Stroke Statistics—2010 Update

(2009) et al.   CIRCULATION

Systemic Lipopolysaccharide Protects the Brain from Ischemic Injury by Reprogramming the Response of the Brain to Stroke: A Critical Role for IRF3

(2009) B. Marsh et al.   JOURNAL OF NEUROSCIENCE

Microglial Involvement in Neuroplastic Changes Following Focal Brain Ischemia in Rats

(2009) Alexandre Madinier et al.   PLoS One

Apoptotic Mechanisms After Cerebral Ischemia

(2009) Brad R.S. Broughton et al.   STROKE

TLR3: Interferon induction by double-stranded RNA including poly(I:C)☆

(2008) M MATSUMOTO et al.   ADVANCED DRUG DELIVERY REVIEWS

Toll-Like Receptor 9: A New Target of Ischemic Preconditioning in the Brain

(2008) Susan L Stevens et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events

(2008) Karen A. Cavassani et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Preconditioning with a TLR2 specific ligand increases resistance to cerebral ischemia/reperfusion injury

(2008) Fang Hua et al.   JOURNAL OF NEUROIMMUNOLOGY