Smad ubiquitination regulatory factor-2 controls gap junction intercellular communication by modulating endocytosis and degradation of connexin43

Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner

(2012) Eloy Bejarano et al.   MOLECULAR BIOLOGY OF THE CELL

Endocytosis and post-endocytic sorting of connexins

(2011) Edward Leithe et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome

(2011) Solveig Sirnes et al.   INTERNATIONAL JOURNAL OF CANCER

Autophagy: a pathway that contributes to connexin degradation

(2011) A. Lichtenstein et al.   JOURNAL OF CELL SCIENCE

Cargo-Dependent Degradation of ESCRT-I as a Feedback Mechanism to Modulate Endosomal Sorting

(2011) Lene Malerød et al.   TRAFFIC

The Tumor-Suppressive Function of Connexin43 in Keratinocytes Is Mediated in Part via Interaction with Caveolin-1

(2010) S. Langlois et al.   CANCER RESEARCH

Ubiquitin: Same Molecule, Different Degradation Pathways

(2010) Michael J. Clague et al.   CELL

Regulation of gap junction intercellular communication by the ubiquitin system

(2010) Ane Kjenseth et al.   CELLULAR SIGNALLING

Ultrastructure and Regulation of Lateralized Connexin43 in the Failing Heart

(2010) Geoffrey G. Hesketh et al.   CIRCULATION RESEARCH

Cx43 suppresses mammary tumor metastasis to the lung in a Cx43 mutant mouse model of human disease

(2010) I Plante et al.   ONCOGENE

Interplay between PKC and the MAP kinase pathway in Connexin43 phosphorylation and inhibition of gap junction intercellular communication

(2009) Solveig Sirnes et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Connexin43 phosphorylation: structural changes and biological effects

(2009) Joell L. Solan et al.   BIOCHEMICAL JOURNAL

Smad Ubiquitination Regulatory Factor 2 Promotes Metastasis of Breast Cancer Cells by Enhancing Migration and Invasiveness

(2009) C. Jin et al.   CANCER RESEARCH

The TSG101 protein binds to connexins and is involved in connexin degradation

(2009) Tanja Auth et al.   EXPERIMENTAL CELL RESEARCH

Eps15 interacts with ubiquitinated Cx43 and mediates its internalization

(2009) Henrique Girão et al.   EXPERIMENTAL CELL RESEARCH

Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101

(2009) E. Leithe et al.   JOURNAL OF CELL SCIENCE

Gap Junction Turnover Is Achieved by the Internalization of Small Endocytic Double-Membrane Vesicles

(2009) Matthias M. Falk et al.   MOLECULAR BIOLOGY OF THE CELL

New roles for endosomes: from vesicular carriers to multi-purpose platforms

(2009) Gwyn W. Gould et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Smurf2 as a novel mitotic regulator: From the spindle assembly checkpoint to tumorigenesis

(2009) Evan C Osmundson et al.   Cell Division

The detergent resistance of Connexin43 is lost upon TPA or EGF treatment and is an early step in gap junction endocytosis

(2008) Solveig Sirnes et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Clathrin and Cx43 gap junction plaque endoexocytosis

(2008) Beth M. Nickel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The HECT Family of E3 Ubiquitin Ligases: Multiple Players in Cancer Development

(2008) Francesca Bernassola et al.   CANCER CELL

Regulation of TGF-β family signaling by E3 ubiquitin ligases

(2008) Yasumichi Inoue et al.   CANCER SCIENCE

The HECT E3 ligase Smurf2 is required for Mad2-dependent spindle assembly checkpoint

(2008) Evan C. Osmundson et al.   JOURNAL OF CELL BIOLOGY