The GPR55 antagonist CID16020046 protects against intestinal inflammation

Synergistic effects of NOD1 or NOD2 and TLR4 activation on mouse sickness behavior in relation to immune and brain activity markers

(2015) Aitak Farzi et al.   BRAIN BEHAVIOR AND IMMUNITY

Palmitoylethanolamide, a naturally occurring lipid, is an orally effective intestinal anti-inflammatory agent

(2014) Francesca Borrelli et al.   BRITISH JOURNAL OF PHARMACOLOGY

Heteromerization of GPR55 and cannabinoid CB2receptors modulates signalling

(2014) N A Balenga et al.   BRITISH JOURNAL OF PHARMACOLOGY

The differential characterization of GPR55 receptor in human peripheral blood reveals a distinctive expression in monocytes and NK cells and a proinflammatory role in these innate cells

(2014) Valerio Chiurchiù et al.   INTERNATIONAL IMMUNOLOGY

Targeting CB2-GPR55 Receptor Heteromers Modulates Cancer Cell Signaling

(2014) Estefanía Moreno et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intestinal anti-inflammatory activity of the Serpylli herba extract in experimental models of rodent colitis

(2014) Francesca Algieri et al.   Journal of Crohns & Colitis

Opposing Roles of Prostaglandin D2Receptors in Ulcerative Colitis

(2014) Eva M. Sturm et al.   JOURNAL OF IMMUNOLOGY

Anthocyanin-rich fractions from red raspberries attenuate inflammation in both RAW264.7 macrophages and a mouse model of colitis

(2014) Li Li et al.   Scientific Reports

Identification of the GPR55 Antagonist Binding Site Using a Novel Set of High-Potency GPR55 Selective Ligands

(2013) Evangelia Kotsikorou et al.   BIOCHEMISTRY

Cannabis Induces a Clinical Response in Patients With Crohn's Disease: A Prospective Placebo-Controlled Study

(2013) Timna Naftali et al.   Clinical Gastroenterology and Hepatology

A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice

(2013) Kun Li et al.   NEUROPHARMACOLOGY

GPR55, a G-Protein Coupled Receptor for Lysophosphatidylinositol, Plays a Role in Motor Coordination

(2013) Chia-Shan Wu et al.   PLoS One

A potential role for GPR55 in gastrointestinal functions

(2012) Rudolf Schicho et al.   CURRENT OPINION IN PHARMACOLOGY

The Cannabinoid Receptor CB1 Modulates the Signaling Properties of the Lysophosphatidylinositol Receptor GPR55

(2012) Julia Kargl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Endocannabinoids Anandamide and Virodhamine Modulate the Activity of the Candidate Cannabinoid Receptor GPR55

(2012) Haleli Sharir et al.   Journal of Neuroimmune Pharmacology

Topical and Systemic Cannabidiol Improves Trinitrobenzene Sulfonic Acid Colitis in Mice

(2012) Rudolf Schicho et al.   PHARMACOLOGY

Evidence for the Putative Cannabinoid Receptor (GPR55)-Mediated Inhibitory Effects on Intestinal Contractility in Mice

(2012) Gracious R. Ross et al.   PHARMACOLOGY

GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils

(2011) Nariman A B Balenga et al.   CELL RESEARCH

Minireview: Recent Developments in the Physiology and Pathology of the Lysophosphatidylinositol-Sensitive Receptor GPR55

(2011) Christopher M. Henstridge et al.   MOLECULAR ENDOCRINOLOGY

A novel CB receptor GPR55 and its ligands are involved in regulation of gut movement in rodents

(2011) X.-H. Lin et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Prostanoid signaling: Dual role for prostaglandin E2 in neurotoxicity

(2011) Dejan Milatovic et al.   NEUROTOXICOLOGY

Cannabinoid receptor-2 (CB2) agonist ameliorates colitis in IL-10−/− mice by attenuating the activation of T cells and promoting their apoptosis

(2011) Udai P. Singh et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Increased expression of lipocalin-type-prostaglandin D synthase in ulcerative colitis and exacerbating role in murine colitis

(2010) Ryota Hokari et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

GPR55 ligands promote receptor coupling to multiple signalling pathways

(2010) Christopher M Henstridge et al.   BRITISH JOURNAL OF PHARMACOLOGY

STAT3 and its activators in intestinal defense and mucosal homeostasis

(2010) Petr Hruz et al.   CURRENT OPINION IN GASTROENTEROLOGY

The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment

(2010) Rudolf Schicho et al.   INFLAMMATORY BOWEL DISEASES

The orphan G protein-coupled receptor GPR55 promotes cancer cell proliferation via ERK

(2010) C Andradas et al.   ONCOGENE

Cannabinoids and the gut: New developments and emerging concepts

(2010) Angelo A. Izzo et al.   PHARMACOLOGY & THERAPEUTICS

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

(2009) Sergei Grivennikov et al.   CANCER CELL

The role of COX-2 in intestinal inflammation and colorectal cancer

(2009) D Wang et al.   ONCOGENE

The enigmatic pharmacology of GPR55

(2009) Ruth A. Ross   TRENDS IN PHARMACOLOGICAL SCIENCES

The GPR55 ligand l-α-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation

(2008) Christopher M. Henstridge et al.   FASEB JOURNAL

Distinct Cytokine Patterns Identified from Multiplex Profiles of Murine DSS and TNBS-Induced Colitis

(2008) Philip Alex et al.   INFLAMMATORY BOWEL DISEASES

2-Arachidonoyl-sn-glycero-3-phosphoinositol: A Possible Natural Ligand for GPR55

(2008) S. Oka et al.   JOURNAL OF BIOCHEMISTRY

Targeting endocannabinoid degradation protects against experimental colitis in mice: involvement of CB1 and CB2 receptors

(2008) Martin A. Storr et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain

(2008) Penny C. Staton et al.   PAIN

GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current

(2008) J. E. Lauckner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The orphan receptor GPR55 is a novel cannabinoid receptor

(2007) E Ryberg et al.   BRITISH JOURNAL OF PHARMACOLOGY