Targeting CB2-GPR55 Receptor Heteromers Modulates Cancer Cell Signaling

Antagonists for the Orphan G-Protein-Coupled Receptor GPR55 Based on a Coumarin Scaffold

(2013) Viktor Rempel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Detection of antigen interactions ex vivo by proximity ligation assay: endogenous dopamine D2-adenosine A2A receptor complexes in the striatum

(2012) Pierre Trifilieff et al.   BIOTECHNIQUES

The Cannabinoid Receptor CB1 Modulates the Signaling Properties of the Lysophosphatidylinositol Receptor GPR55

(2012) Julia Kargl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cannabinoid Receptors CB1and CB2Form Functional Heteromers in Brain

(2012) Lucía Callén et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The orphan receptor GPR55 drives skin carcinogenesis and is upregulated in human squamous cell carcinomas

(2012) E Pérez-Gómez et al.   ONCOGENE

Stimulation of the midkine/ALK axis renders glioma cells resistant to cannabinoid antitumoral action

(2011) M Lorente et al.   CELL DEATH AND DIFFERENTIATION

GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils

(2011) Nariman A B Balenga et al.   CELL RESEARCH

AT1R-CB1R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II

(2011) Raphael Rozenfeld et al.   EMBO JOURNAL

Modulation of l-α-Lysophosphatidylinositol/GPR55 Mitogen-activated Protein Kinase (MAPK) Signaling by Cannabinoids

(2011) Sharon Anavi-Goffer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Minireview: Recent Developments in the Physiology and Pathology of the Lysophosphatidylinositol-Sensitive Receptor GPR55

(2011) Christopher M. Henstridge et al.   MOLECULAR ENDOCRINOLOGY

Dopamine D4 receptor, but not the ADHD-associated D4.7 variant, forms functional heteromers with the dopamine D2S receptor in the brain

(2011) S González et al.   MOLECULAR PSYCHIATRY

Receptors and Channels Targeted by Synthetic Cannabinoid Receptor Agonists and Antagonists

(2010) R. Pertwee   CURRENT MEDICINAL CHEMISTRY

Interactions between Intracellular Domains as Key Determinants of the Quaternary Structure and Function of Receptor Heteromers

(2010) Gemma Navarro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deconvolution of complex G protein–coupled receptor signaling in live cells using dynamic mass redistribution measurements

(2010) Ralf Schröder et al.   NATURE BIOTECHNOLOGY

The orphan G protein-coupled receptor GPR55 promotes cancer cell proliferation via ERK

(2010) C Andradas et al.   ONCOGENE

The putative cannabinoid receptor GPR55 defines a novel autocrine loop in cancer cell proliferation

(2010) R Piñeiro et al.   ONCOGENE

International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2

(2010) R. G. Pertwee et al.   PHARMACOLOGICAL REVIEWS

Receptor heteromerization and drug discovery

(2010) Raphael Rozenfeld et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Emerging strategies for exploiting cannabinoid receptor agonists as medicines

(2009) Roger G Pertwee   BRITISH JOURNAL OF PHARMACOLOGY

Long-Term Fluoxetine Treatment Modulates Cannabinoid Type 1 Receptor-Mediated Inhibition of Adenylyl Cyclase in the Rat Prefrontal Cortex through 5-Hydroxytryptamine1A Receptor-Dependent Mechanisms

(2009) S. Mato et al.   MOLECULAR PHARMACOLOGY

The structure and function of G-protein-coupled receptors

(2009) Daniel M. Rosenbaum et al.   NATURE

The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo

(2009) L. S. Whyte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The enigmatic pharmacology of GPR55

(2009) Ruth A. Ross   TRENDS IN PHARMACOLOGICAL SCIENCES

Heat-treated Saccharomyces cerevisiae for antimony speciation and antimony(III) preconcentration in water samples

(2008) Sébastien Marcellino et al.   ANALYTICA CHIMICA ACTA

The GPR55 ligand l-α-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation

(2008) Christopher M. Henstridge et al.   FASEB JOURNAL

Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay

(2008) Ola Söderberg et al.   METHODS

Detection of heteromerization of more than two proteins by sequential BRET-FRET

(2008) Paulina Carriba et al.   NATURE METHODS

Novel cannabinoid receptors

(2007) A J Brown   BRITISH JOURNAL OF PHARMACOLOGY

μ opioid and CB1 cannabinoid receptor interactions: reciprocal inhibition of receptor signaling and neuritogenesis

(2006) Carl Rios et al.   BRITISH JOURNAL OF PHARMACOLOGY