Chromosome structural anomalies due to aberrant spindle forces exerted at gene editing sites in meiosis

A safer, urea-based in situ hybridization method improves detection of gene expression in diverse animal species

(2018) Chiara Sinigaglia et al.   DEVELOPMENTAL BIOLOGY

Structural Variation Shapes the Landscape of Recombination in Mouse

(2017) Andrew P. Morgan et al.   GENETICS

Plk4 and Aurora A cooperate in the initiation of acentriolar spindle assembly in mammalian oocytes

(2017) Leah Bury et al.   JOURNAL OF CELL BIOLOGY

Structural Variation Shapes the Landscape of Recombination in Mouse

(2017) Andrew P. Morgan et al.   GENETICS

Attachment issues: kinetochore transformations and spindle checkpoint silencing

(2016) Banafsheh Etemad et al.   CURRENT OPINION IN CELL BIOLOGY

Meiotic spindle assembly and chromosome segregation in oocytes

(2016) Isma Bennabi et al.   JOURNAL OF CELL BIOLOGY

Chromosomal microarray testing identifies a 4p terminal region associated with seizures in Wolf–Hirschhorn syndrome

(2016) Karen S Ho et al.   JOURNAL OF MEDICAL GENETICS

How oocytes try to get it right: spindle checkpoint control in meiosis

(2015) Sandra A. Touati et al.   CHROMOSOMA

Chromothripsis from DNA damage in micronuclei

(2015) Cheng-Zhong Zhang et al.   NATURE

Transient PLK4 overexpression accelerates tumorigenesis in p53-deficient epidermis

(2015) Özdemirhan Serçin et al.   NATURE CELL BIOLOGY

Error-prone chromosome-mediated spindle assembly favors chromosome segregation defects in human oocytes

(2015) Z. Holubcova et al.   SCIENCE

Joined at the hip: kinetochores, microtubules, and spindle assembly checkpoint signaling

(2015) Carlos Sacristan et al.   TRENDS IN CELL BIOLOGY

DNA damage-induced metaphase I arrest is mediated by the spindle assembly checkpoint and maternal age

(2015) Petros Marangos et al.   Nature Communications

DNA damage induces a meiotic arrest in mouse oocytes mediated by the spindle assembly checkpoint

(2015) Josie K. Collins et al.   Nature Communications

A three-step MTOC fragmentation mechanism facilitates bipolar spindle assembly in mouse oocytes

(2015) Dean Clift et al.   Nature Communications

Targeted sequencing by proximity ligation for comprehensive variant detection and local haplotyping

(2014) Paula J P de Vree et al.   NATURE BIOTECHNOLOGY

Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy

(2014) Carol-Anne Martin et al.   NATURE GENETICS

Rebuilding MTOCs upon centriole loss during mouse oogenesis

(2013) Małgorzata Łuksza et al.   DEVELOPMENTAL BIOLOGY

Spindle Formation in the Mouse Embryo Requires Plk4 in the Absence of Centrioles

(2013) Paula A. Coelho et al.   DEVELOPMENTAL CELL

Statistics of Time-Dependent Rupture of Single ds-DNA

(2013) Hua Liang et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Centrosome amplification causes microcephaly

(2013) Véronique Marthiens et al.   NATURE CELL BIOLOGY

Timing of anaphase-promoting complex activation in mouse oocytes is predicted by microtubule-kinetochore attachment but not by bivalent alignment or tension

(2012) S. I. R. Lane et al.   DEVELOPMENT

Linking abnormal mitosis to the acquisition of DNA damage

(2012) Neil J. Ganem et al.   JOURNAL OF CELL BIOLOGY

DNA breaks and chromosome pulverization from errors in mitosis

(2012) Karen Crasta et al.   NATURE

Subdiffraction-resolution fluorescence microscopy reveals a domain of the centrosome critical for pericentriolar material organization

(2012) V. Mennella et al.   NATURE CELL BIOLOGY

Subdiffraction imaging of centrosomes reveals higher-order organizational features of pericentriolar material

(2012) Steffen Lawo et al.   NATURE CELL BIOLOGY

Error-prone mammalian female meiosis from silencing the spindle assembly checkpoint without normal interkinetochore tension

(2012) A. Kolano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acentrosomal spindle assembly and chromosome segregation during oocyte meiosis

(2012) Julien Dumont et al.   TRENDS IN CELL BIOLOGY

Structured illumination of the interface between centriole and peri-centriolar material

(2012) J. Fu et al.   Open Biology

3D-structured illumination microscopy provides novel insight into architecture of human centrosomes

(2012) Katharina F. Sonnen et al.   Biology Open

Complete Kinetochore Tracking Reveals Error-Prone Homologous Chromosome Biorientation in Mammalian Oocytes

(2011) Tomoya S. Kitajima et al.   CELL

Oocyte-Specific Differences in Cell-Cycle Control Create an Innate Susceptibility to Meiotic Errors

(2011) So Iha Nagaoka et al.   CURRENT BIOLOGY

Mps1 at kinetochores is essential for female mouse meiosis I

(2011) K. Hached et al.   DEVELOPMENT

HURP permits MTOC sorting for robust meiotic spindle bipolarity, similar to extra centrosome clustering in cancer cells

(2010) Manuel Breuer et al.   JOURNAL OF CELL BIOLOGY

A mechanism linking extra centrosomes to chromosomal instability

(2009) Neil J. Ganem et al.   NATURE

Subdiffraction Multicolor Imaging of the Nuclear Periphery with 3D Structured Illumination Microscopy

(2008) L. Schermelleh et al.   SCIENCE