DNA breaks and chromosomal aberrations arise when replication meets base excision repair

Co-ordination of base excision repair and genome stability

(2013) Jason L. Parsons et al.   DNA REPAIR

Mammalian Base Excision Repair: the Forgotten Archangel

(2013) Grigory L. Dianov et al.   NUCLEIC ACIDS RESEARCH

Aag DNA Glycosylase Promotes Alkylation-Induced Tissue Damage Mediated by Parp1

(2013) Jennifer A. Calvo et al.   PLoS Genetics

Synthesis, Biological Evaluation, and Structure–Activity Relationships of a Novel Class of Apurinic/Apyrimidinic Endonuclease 1 Inhibitors

(2012) Ganesha Rai et al.   JOURNAL OF MEDICINAL CHEMISTRY

Homologous recombination repairs secondary replication induced DNA double-strand breaks after ionizing radiation

(2012) Petra Groth et al.   NUCLEIC ACIDS RESEARCH

γH2AX foci analysis for monitoring DNA double-strand break repair: Strengths, limitations and optimization

(2011) Markus Löbrich et al.   CELL CYCLE

Alkylation Base Damage Is Converted into Repairable Double-Strand Breaks and Complex Intermediates in G2 Cells Lacking AP Endonuclease

(2011) Wenjian Ma et al.   PLoS Genetics

Regulation of Homologous Recombination in Eukaryotes

(2010) Wolf-Dietrich Heyer et al.   Annual Review of Genetics

Homologous recombination protects mammalian cells from replication-associated DNA double-strand breaks arising in response to methyl methanesulfonate

(2010) Teodora Nikolova et al.   DNA REPAIR

Methylated DNA Causes a Physical Block to Replication Forks Independently of Damage Signalling, O6-Methylguanine or DNA Single-Strand Breaks and Results in DNA Damage

(2010) Petra Groth et al.   JOURNAL OF MOLECULAR BIOLOGY

Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair

(2010) Eva Petermann et al.   MOLECULAR CELL

Eukaryotic DNA replication origins: many choices for appropriate answers

(2010) Marcel Méchali   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CtIP and MRN promote non-homologous end-joining of etoposide-induced DNA double-strand breaks in G1

(2010) Verena Quennet et al.   NUCLEIC ACIDS RESEARCH

Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice

(2009) Lisiane B. Meira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

XRCC1 and DNA polymerase β in cellular protection against cytotoxic DNA single-strand breaks

(2008) Julie K Horton et al.   CELL RESEARCH

The methyl methanesulfonate induced S-phase delay in XRCC1-deficient cells requires ATM and ATR

(2008) Reto Brem et al.   DNA REPAIR

Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair

(2008) Wen-Cheng Chou et al.   EMBO JOURNAL

Single-strand break repair and genetic disease

(2008) Keith W. Caldecott   NATURE REVIEWS GENETICS