Complexin synchronizes primed vesicle exocytosis and regulates fusion pore dynamics

Subtle Interplay between Synaptotagmin and Complexin Binding to the SNARE Complex

(2013) Junjie Xu et al.   JOURNAL OF MOLECULAR BIOLOGY

Doc2b Synchronizes Secretion from Chromaffin Cells by Stimulating Fast and Inhibiting Sustained Release

(2013) P. S. Pinheiro et al.   JOURNAL OF NEUROSCIENCE

Complexin Activates Exocytosis of Distinct Secretory Vesicles Controlled by Different Synaptotagmins

(2013) P. Cao et al.   JOURNAL OF NEUROSCIENCE

Complexin facilitates exocytosis and synchronizes vesicle release in two secretory model systems

(2013) Ming-Yi Lin et al.   JOURNAL OF PHYSIOLOGY-LONDON

Synaptic Vesicles Position Complexin to Block Spontaneous Fusion

(2013) Rachel T. Wragg et al.   NEURON

Complexin Controls Spontaneous and Evoked Neurotransmitter Release by Regulating the Timing and Properties of Synaptotagmin Activity

(2012) R. A. Jorquera et al.   JOURNAL OF NEUROSCIENCE

C-Terminal Complexin Sequence Is Selectively Required for Clamping and Priming But Not for Ca2+ Triggering of Synaptic Exocytosis

(2012) Y. J. Kaeser-Woo et al.   JOURNAL OF NEUROSCIENCE

Complexin Maintains Vesicles in the Primed State in C. elegans

(2011) Robert J. Hobson et al.   CURRENT BIOLOGY

Complexin Has Opposite Effects on Two Modes of Synaptic Vesicle Fusion

(2011) Jesse A. Martin et al.   CURRENT BIOLOGY

A conformational switch in complexin is required for synaptotagmin to trigger synaptic fusion

(2011) Shyam S Krishnakumar et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Complexin cross-links prefusion SNAREs into a zigzag array

(2011) Daniel Kümmel et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SNARE Force Synchronizes Synaptic Vesicle Fusion and Controls the Kinetics of Quantal Synaptic Transmission

(2010) R. E. Guzman et al.   JOURNAL OF NEUROSCIENCE

Comparative analysis of Drosophila and mammalian complexins as fusion clamps and facilitators of neurotransmitter release

(2010) Richard W. Cho et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Real-time visualization of complexin during single exocytic events

(2010) Seong J An et al.   NATURE NEUROSCIENCE

Binding of the complexin N terminus to the SNARE complex potentiates synaptic-vesicle fusogenicity

(2010) Mingshan Xue et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Complexin Clamps Asynchronous Release by Blocking a Secondary Ca2+ Sensor via Its Accessory α Helix

(2010) Xiaofei Yang et al.   NEURON

Complexin: Does It Deserve Its Name?

(2010) Erwin Neher   NEURON

Push-and-pull regulation of the fusion pore by synaptotagmin-7

(2010) M. Segovia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Doc2b Is a High-Affinity Ca2+ Sensor for Spontaneous Neurotransmitter Release

(2010) A. J. Groffen et al.   SCIENCE

Concurrent Binding of Complexin and Synaptotagmin to Liposome-Embedded SNARE Complexes†

(2009) Michael C. Chicka et al.   BIOCHEMISTRY

A role of complexin-lipid interactions in membrane fusion

(2009) Florian Seiler et al.   FEBS LETTERS

Complexin-I Is Required for High-Fidelity Transmission at the Endbulb of Held Auditory Synapse

(2009) N. Strenzke et al.   JOURNAL OF NEUROSCIENCE

Tilting the Balance between Facilitatory and Inhibitory Functions of Mammalian and Drosophila Complexins Orchestrates Synaptic Vesicle Exocytosis

(2009) Mingshan Xue et al.   NEURON

The carboxy-terminal domain of complexin I stimulates liposome fusion

(2009) Jörg Malsam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative Zippering as an On-Off Switch for SNARE-Mediated Fusion

(2009) C. G. Giraudo et al.   SCIENCE

Complexin Controls the Force Transfer from SNARE Complexes to Membranes in Fusion

(2009) A. Maximov et al.   SCIENCE

How Does Synaptotagmin Trigger Neurotransmitter Release?

(2008) Edwin R. Chapman   Annual Review of Biochemistry

Distinct Domains of Complexins Bind SNARE Complexes and Clamp Fusionin Vitro

(2008) Claudio G. Giraudo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synaptotagmin-1 Utilizes Membrane Bending and SNARE Binding to Drive Fusion Pore Expansion

(2008) Kara L. Lynch et al.   MOLECULAR BIOLOGY OF THE CELL

Complexin and Ca2+ stimulate SNARE-mediated membrane fusion

(2008) Tae-Young Yoon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Synaptotagmin-1 and -7 are functionally overlapping Ca2+ sensors for exocytosis in adrenal chromaffin cells

(2008) J.-S. Schonn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complexin II plays a positive role in Ca2+-triggered exocytosis by facilitating vesicle priming

(2008) H. Cai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complexins facilitate neurotransmitter release at excitatory and inhibitory synapses in mammalian central nervous system

(2008) M. Xue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA