Rutin, A Natural Flavonoid Protects PC12 Cells Against Sodium Nitroprusside-Induced Neurotoxicity Through Activating PI3K/Akt/mTOR and ERK1/2 Pathway

Gardenamide A attenuated cell apoptosis induced by serum deprivation insult via the ERK1/2 and PI3K/AKT signaling pathways

(2015) R. Wang et al.   NEUROSCIENCE

Stereoselective Reduction of 1-O-Isopropyloxygenipin Enhances Its Neuroprotective Activity in Neuronal Cells from Apoptosis Induced by Sodium Nitroprusside

(2014) Rikang Wang et al.   ChemMedChem

Glutamate Excitotoxicity Activates the MAPK/ERK Signaling Pathway and Induces the Survival of Rat Hippocampal Neurons In Vivo

(2013) Daniel Ortuño-Sahagún et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Rutin activates the MAPK pathway and BDNF gene expression on beta-amyloid induced neurotoxicity in rats

(2013) Sahar Moghbelinejad et al.   TOXICOLOGY LETTERS

The protective effect of rutin against ischemia/reperfusion-associated hemodynamic alteration through antioxidant activity

(2012) Bidur Bhandary et al.   ARCHIVES OF PHARMACAL RESEARCH

Edaravone Protects HT22 Neurons from H2O2-induced Apoptosis by Inhibiting the MAPK Signaling Pathway

(2012) Zhong-Yan Zhao et al.   CNS Neuroscience & Therapeutics

Cooperative action of JNK and AKT/mTOR in 1-methyl-4-phenylpyridinium-induced autophagy of neuronal PC12 cells

(2012) Jezabel Rodríguez-Blanco et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Rutin inhibits β-amyloid aggregation and cytotoxicity, attenuates oxidative stress, and decreases the production of nitric oxide and proinflammatory cytokines

(2012) Shao-wei Wang et al.   NEUROTOXICOLOGY

Taurine attenuates methamphetamine-induced autophagy and apoptosis in PC12 cells through mTOR signaling pathway

(2012) Yan Li et al.   TOXICOLOGY LETTERS

Protective effect of rutin on testicular ischemia-reperfusion injury

(2011) Si-Ming Wei et al.   JOURNAL OF PEDIATRIC SURGERY

Quercetin and rutin exhibit antiamyloidogenic and fibril-disaggregating effects in vitro and potent antioxidant activity in APPswe cells

(2011) Karim Jiménez-Aliaga et al.   LIFE SCIENCES

Tacrine(2)–ferulic acid, a novel multifunctional dimer, attenuates 6-hydroxydopamine-induced apoptosis in PC12 cells by activating Akt pathway

(2011) Huan Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

Mitochondrial dysfunction in brain aging: Role of oxidative stress and cardiolipin

(2011) Giuseppe Paradies et al.   NEUROCHEMISTRY INTERNATIONAL

Chemopreventive effect of dietary polyphenols in colorectal cancer cell lines

(2011) João R. Araújo et al.   NUTRITION RESEARCH

Calcium Signaling Is Involved in Cadmium-Induced Neuronal Apoptosis via Induction of Reactive Oxygen Species and Activation of MAPK/mTOR Network

(2011) Baoshan Xu et al.   PLoS One

Hydrogen peroxide inhibits mTOR signaling by activation of AMPKα leading to apoptosis of neuronal cells

(2010) Long Chen et al.   LABORATORY INVESTIGATION

Metals, oxidative stress and neurodegenerative disorders

(2010) Klaudia Jomova et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Rutin from Lonicera japonica inhibits myocardial ischemia/reperfusion-induced apoptosis in vivo and protects H9c2 cells against hydrogen peroxide-mediated injury via ERK1/2 and PI3K/Akt signals in vitro

(2009) Jae Ju Jeong et al.   FOOD AND CHEMICAL TOXICOLOGY

Glucagon-like peptide-1 (GLP-1) protects against methylglyoxal-induced PC12 cell apoptosis through the PI3K/Akt/mTOR/GCLc/redox signaling pathway

(2009) R. Kimura et al.   NEUROSCIENCE

Calcium homeostasis, selective vulnerability and Parkinson's disease

(2009) C. Savio Chan et al.   TRENDS IN NEUROSCIENCES

Resveratrol exerts its neuroprotective effect by modulating mitochondrial dysfunctions and associated cell death during cerebral ischemia

(2008) Seema Yousuf et al.   BRAIN RESEARCH

Heart Disease and Stroke Statistics—2009 Update

(2008) et al.   CIRCULATION

Protective role of new nitrogen compounds on ROS/RNS-mediated damage to PC12 cells

(2008) João P. Silva et al.   FREE RADICAL RESEARCH