Glutamate Excitotoxicity Activates the MAPK/ERK Signaling Pathway and Induces the Survival of Rat Hippocampal Neurons In Vivo

Spatiotemporal resolution of BDNF neuroprotection against glutamate excitotoxicity in cultured hippocampal neurons

(2013) C.V. Melo et al.   NEUROSCIENCE

Monoamine Oxidase Inhibitors as Neuroprotective Agents in Age-Dependent Neurodegenerative Disorders

(2012) Makoto Naoi et al.   CURRENT PHARMACEUTICAL DESIGN

Protective Effects of mGluR5 Positive Modulators Against Traumatic Neuronal Injury Through PKC-Dependent Activation of MEK/ERK Pathway

(2012) Tao Chen et al.   NEUROCHEMICAL RESEARCH

Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism

(2012) K. Thangavelu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

VEGF protects rat cortical neurons from mechanical trauma injury induced apoptosis via the MEK/ERK pathway

(2011) Yihui Ma et al.   BRAIN RESEARCH BULLETIN

ERK1/2 activation is involved in the neuroprotective action of P2Y13 and P2X7 receptors against glutamate excitotoxicity in cerebellar granule neurons

(2011) Felipe Ortega et al.   NEUROPHARMACOLOGY

Pigment epithelium-derived factor (PEDF) protects cortical neurons in vitro from oxidant injury by activation of extracellular signal-regulated kinase (ERK) 1/2 and induction of Bcl-2

(2011) A. Sanchez et al.   NEUROSCIENCE RESEARCH

Investigational Therapies for Ischemic Stroke: Neuroprotection and Neurorecovery

(2011) Preeti Sahota et al.   Neurotherapeutics

Paeonol Prevents Excitotoxicity in Rat Pheochromocytoma PC12 Cells via Downregulation of ERK Activation and Inhibition of Apoptosis

(2011) Xuncui Wang et al.   PLANTA MEDICA

ERK/MAPK Is Essential for Endogenous Neuroprotection in SCN2.2 Cells

(2011) Sumedha W. Karmarkar et al.   PLoS One

Molecular and cellular mechanisms of excitotoxic neuronal death

(2010) Yan Wang et al.   APOPTOSIS

Pathological roles of MAPK signaling pathways in human diseases

(2010) Eun Kyung Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Dopamine and Glutamate in Huntington's Disease: A Balancing Act

(2010) Véronique M. André et al.   CNS Neuroscience & Therapeutics

New Therapeutic Strategy for Parkinsons and Alzheimers Disease

(2010) E. Esposito et al.   CURRENT MEDICINAL CHEMISTRY

Microarray analysis of rat hippocampus exposed to excitotoxicity: Reversal Na+/Ca2+ exchanger NCX3 is overexpressed in glial cells

(2010) Daniel Ortuño-Sahagún et al.   HIPPOCAMPUS

Identification of Potentially Neuroprotective Genes Upregulated by Neurotrophin Treatment of CA3 Neurons in the Injured Brain

(2010) Saafan Z. Malik et al.   JOURNAL OF NEUROTRAUMA

Glutamate receptors, neurotoxicity and neurodegeneration

(2010) Anthony Lau et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases

(2009) Xiao-xia Dong et al.   ACTA PHARMACOLOGICA SINICA

ACh receptors link two signaling pathways to neuroprotection against glutamate-induced excitotoxicity in isolated RGCs

(2009) Chinwe O. Asomugha et al.   JOURNAL OF NEUROCHEMISTRY

Senescence marker protein 30 is up-regulated in kainate-induced hippocampal damage through ERK-mediated astrocytosis

(2009) Tae Gen Son et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Activation of p38 Mitogen-Activated Protein Kinase Is Required for Death Receptor-Independent Caspase-8 Activation and Cell Death in Response to Sphingosine

(2009) C.-H. Yoon et al.   MOLECULAR CANCER RESEARCH

Metabotropic Glutamate Receptor-Mediated Long-Term Depression: Molecular Mechanisms

(2009) C. M. Gladding et al.   PHARMACOLOGICAL REVIEWS

GDNF Selectively Induces Microglial Activation and Neuronal Survival in CA1/CA3 Hippocampal Regions Exposed to NMDA Insult through Ret/ERK Signalling

(2009) Francesca Boscia et al.   PLoS One

P38 MAP Kinase inhibition promotes primary tumour growth via VEGF independent mechanism

(2009) Adrian W O'Sullivan et al.   World Journal of Surgical Oncology

Glutamate forward and reverse transport: From molecular mechanism to transporter-mediated release after ischemia

(2008) Christof Grewer et al.   IUBMB LIFE

Roles of distinct glutamate receptors in induction of anti-Hebbian long-term potentiation

(2008) Dimitri M. Kullmann et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mitogen-activated protein kinase kinase 1/2 inhibitors and 17-allylamino-17-demethoxygeldanamycin synergize to kill human gastrointestinal tumor cells in vitro via suppression of c-FLIP-s levels and activation of CD95

(2008) M. A. Park et al.   MOLECULAR CANCER THERAPEUTICS

Differential activation of mitogen-activated protein kinase signalling pathways in the hippocampus of CRND8 transgenic mouse, a model of Alzheimer's disease

(2008) M.G. Giovannini et al.   NEUROSCIENCE

Neuroprotection by Imipramine against lipopolysaccharide-induced apoptosis in hippocampus-derived neural stem cells mediated by activation of BDNF and the MAPK pathway

(2007) Chi-Hsien Peng et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY