An energetic orphan in an endocrine tissue: A revised perspective of the function of estrogen receptor-related receptor alpha in bone and cartilage

Intracellular VEGF regulates the balance between osteoblast and adipocyte differentiation

(2012) Yanqiu Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Estrogen-related receptor α regulates osteoblast differentiation via Wnt/β-catenin signaling

(2012) Kathryn L Auld et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

The contribution of bone to whole-organism physiology

(2012) Gérard Karsenty et al.   NATURE

Estrogen receptor-related receptor α regulation by interleukin-1β in prostaglandin E2- and cAMP-dependent pathways in osteoarthritic chondrocytes

(2011) Edith Bonnelye et al.   ARTHRITIS AND RHEUMATISM

Unraveling the role of FoxOs in bone—Insights from mouse models

(2011) Maria Almeida   BONE

Molecular mechanisms involved in the mitogenic effect of lactoferrin in osteoblasts

(2011) Dorit Naot et al.   BONE

Intermittent injections of osteocalcin improve glucose metabolism and prevent type 2 diabetes in mice

(2011) Mathieu Ferron et al.   BONE

The Metabolic Regulator ERRα, a Downstream Target of HER2/IGF-1R, as a Therapeutic Target in Breast Cancer

(2011) Ching-yi Chang et al.   CANCER CELL

Dual Function of ERR  in Breast Cancer and Bone Metastasis Formation: Implication of VEGF and Osteoprotegerin

(2011) A. Fradet et al.   CANCER RESEARCH

A novel quercetin analogue from a medicinal plant promotes peak bone mass achievement and bone healing after injury and exerts an anabolic effect on osteoporotic bone: The role of aryl hydrocarbon receptor as a mediator of osteogenic action

(2011) Kunal Sharan et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Estrogen related receptor α-induced adipogenesis is PGC-1β-dependent

(2011) Dapeng Ju et al.   MOLECULAR BIOLOGY REPORTS

The peroxisome proliferator-activated receptor (PPAR) alpha agonist fenofibrate maintains bone mass, while the PPAR gamma agonist pioglitazone exaggerates bone loss, in ovariectomized rats

(2011) Astrid K Stunes et al.   BMC Endocrine Disorders

FoxOs: Unifying Links Between Oxidative Stress and Skeletal Homeostasis

(2011) Stavroula Kousteni   Current Osteoporosis Reports

ERRα regulates osteoblastic and adipogenic differentiation of mouse bone marrow mesenchymal stem cells

(2010) Ann-Marie Rajalin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Troglitazone is an estrogen-related receptor α and γ inverse agonist

(2010) Yanfei Wang et al.   BIOCHEMICAL PHARMACOLOGY

Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network

(2010) Richard C. Scarpulla   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Lactoferrin as an effector molecule in the skeleton

(2010) Jillian Cornish et al.   BIOMETALS

WNT11 Expression Is Induced by Estrogen-Related Receptor   and  -Catenin and Acts in an Autocrine Manner to Increase Cancer Cell Migration

(2010) M. A. Dwyer et al.   CANCER RESEARCH

Insulin Receptor Signaling in Osteoblasts Regulates Postnatal Bone Acquisition and Body Composition

(2010) Keertik Fulzele et al.   CELL

PGC1β Mediates PPARγ Activation of Osteoclastogenesis and Rosiglitazone-Induced Bone Loss

(2010) Wei Wei et al.   Cell Metabolism

Oestrogen-related receptor alpha inverse agonist XCT-790 arrests A549 lung cancer cell population growth by inducing mitochondrial reactive oxygen species production

(2010) J. Wang et al.   CELL PROLIFERATION

From Estrogen-Centric to Aging and Oxidative Stress: A Revised Perspective of the Pathogenesis of Osteoporosis

(2010) Stavros C. Manolagas   ENDOCRINE REVIEWS

Hypoxia-inducible factor regulates osteoclast-mediated bone resorption: role of angiopoietin-like 4

(2010) Helen J. Knowles et al.   FASEB JOURNAL

Involvement of the orphan nuclear estrogen receptor-related receptor α in osteoclast adhesion and transmigration

(2010) Edith Bonnelye et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Sirtuin 3, a New Target of PGC-1α, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis

(2010) Xingxing Kong et al.   PLoS One

ERR receptors as potential targets in osteoporosis

(2010) Marlène Gallet et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

An Osteoblast-dependent Mechanism Contributes to the Leptin Regulation of Insulin Secretion

(2009) Eiichi Hinoi et al.   Annals of the New York Academy of Sciences

PGC-1α in aging and anti-aging interventions

(2009) Rozalyn Anderson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Estrogen-Related Receptor α Inverse Agonist Enhances Basal Glucose Uptake in Myotubes through Reactive Oxygen Species

(2009) Lihua Chen et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Absence of Estrogen Receptor-Related-α Increases Osteoblastic Differentiation and Cancellous Bone Mineral Density

(2009) I. Delhon et al.   ENDOCRINOLOGY

Wnt11 Promotes Osteoblast Maturation and Mineralization through R-spondin 2

(2009) Michael S. Friedman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Lipid Oxidation Causes Oxidative Stress, Increased Peroxisome Proliferator-activated Receptor-γ Expression, and Diminished Pro-osteogenic Wnt Signaling in the Skeleton

(2009) Maria Almeida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Orphan Nuclear Receptor Estrogen Receptor-related Receptor γ Negatively Regulates BMP2-induced Osteoblast Differentiation and Bone Formation

(2009) Byung-Chul Jeong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The orphan nuclear receptor SHP is a positive regulator of osteoblastic bone formation

(2009) Byung-Chul Jeong et al.   JOURNAL OF BONE AND MINERAL RESEARCH

FoxO1 expression in osteoblasts regulates glucose homeostasis through regulation of osteocalcin in mice

(2009) Marie-Therese Rached et al.   JOURNAL OF CLINICAL INVESTIGATION

Estrogen-related receptor alpha induces the expression of vascular endothelial growth factor in breast cancer cells

(2009) Rebecca A. Stein et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Peroxisome Proliferator-Activated Receptor   Coactivator 1  and Small Heterodimer Partner Differentially Regulate Nuclear Receptor-Dependent Hepatitis B Virus Biosynthesis

(2009) C. R. Ondracek et al.   JOURNAL OF VIROLOGY

Regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) gene expression by glucocorticoids and insulin

(2009) Sara Connaughton et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Physiological Genomics Identifies Estrogen-Related Receptor α as a Regulator of Renal Sodium and Potassium Homeostasis and the Renin-Angiotensin Pathway

(2009) Annie M. Tremblay et al.   MOLECULAR ENDOCRINOLOGY

Coordination of PGC-1β and iron uptake in mitochondrial biogenesis and osteoclast activation

(2009) Kiyo-aki Ishii et al.   NATURE MEDICINE

Absence of ERRα in Female Mice Confers Resistance to Bone Loss Induced by Age or Estrogen-Deficiency

(2009) Catherine Teyssier et al.   PLoS One

Osteoarthritis revisited—again!

(2009) Iain Watt   SKELETAL RADIOLOGY

Transgenic Mice with a Constitutively Active Aryl Hydrocarbon Receptor Display a Gender-Specific Bone Phenotype

(2009) Carolina Wejheden et al.   TOXICOLOGICAL SCIENCES

Different skeletal effects of the peroxisome proliferator activated receptor (PPAR)α agonist fenofibrate and the PPARγ agonist pioglitazone

(2009) Unni Syversen et al.   BMC Endocrine Disorders

Thiazolidinedione-induced skeletal fragility - mechanisms and implications

(2008) Andrew Grey   DIABETES OBESITY & METABOLISM

Transcriptional Control of Energy Homeostasis by the Estrogen-Related Receptors

(2008) Vincent Giguère   ENDOCRINE REVIEWS

The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity

(2008) Eiichi Hinoi et al.   JOURNAL OF CELL BIOLOGY

Suppressing the activity of ERRα in 3T3-L1 adipocytes reduces mitochondrial biogenesis but enhances glycolysis and basal glucose uptake

(2008) Yaohui Nie et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α

(2008) Zoltan Arany et al.   NATURE

Involvement of estrogen-related receptors in transcriptional response to hypoxia and growth of solid tumors

(2008) A. Ao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Osteocalcin differentially regulates β cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice

(2008) Mathieu Ferron et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of the hypoxia-inducible factor-1  pathway accelerates bone regeneration

(2008) C. Wan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estrogen receptor-related receptor-  (ERR- ) is dysregulated in inflammatory arthritis

(2008) E. Bonnelye et al.   RHEUMATOLOGY

ERRα: a metabolic function for the oldest orphan

(2008) Josep A. Villena et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM