The R740S mutation in the V-ATPase a3 subunit increases lysosomal pH, impairs NFATc1 translocation, and decreases in vitro osteoclastogenesis

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

(2014) Daniel J. Klionsky et al.   Autophagy

The small molecule harmine regulates NFATc1 and Id2 expression in osteoclast progenitor cells

(2011) Hiroshi Egusa et al.   BONE

Re-evaluation of antimalarials in treating rheumatic diseases: re-appreciation and insights into new mechanisms of action

(2011) Steven J Katz et al.   CURRENT OPINION IN RHEUMATOLOGY

The V-ATPase a3 subunit mutation R740S is dominant negative and results in osteopetrosis in mice

(2011) Noelle Ochotny et al.   JOURNAL OF BONE AND MINERAL RESEARCH

NFATc1 affects mouse splenic B cell function by controlling the calcineurin–NFAT signaling network

(2011) Sankar Bhattacharyya et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Weak Base-Generating System Suitable for Selective Manipulation of Lysosomal pH

(2011) Luciene R. Carraro-Lacroix et al.   TRAFFIC

Disruption of the Man-6-P Targeting Pathway in Mice Impairs Osteoclast Secretory Lysosome Biogenesis

(2011) Eline van Meel et al.   TRAFFIC

A Rationale for Osteoclast Selectivity of Inhibiting the Lysosomal V-ATPase a3 Isoform

(2010) Jonas K. E. Nyman et al.   CALCIFIED TISSUE INTERNATIONAL

A cation counterflux supports lysosomal acidification

(2010) Benjamin E. Steinberg et al.   JOURNAL OF CELL BIOLOGY

Requirement of Prorenin Receptor and Vacuolar H+-ATPase-Mediated Acidification for Wnt Signaling

(2010) C.-M. Cruciat et al.   SCIENCE

Interaction of calcineurin with substrates and targeting proteins

(2010) Huiming Li et al.   TRENDS IN CELL BIOLOGY

SnapShot: Ca2+-Calcineurin-NFATSignaling

(2009) Gerald R. Crabtree et al.   CELL

Degradation of regulator of calcineurin 1 (RCAN1) is mediated by both chaperone-mediated autophagy and ubiquitin proteasome pathways

(2009) Heng Liu et al.   FASEB JOURNAL

Inhibitors of the V0 subunit of the vacuolar H+-ATPase prevent segregation of lysosomal- and secretory-pathway proteins

(2009) J. A. Sobota et al.   JOURNAL OF CELL SCIENCE

Bone marrow microenvironment controls the in vivo differentiation of murine dendritic cells into osteoclasts

(2008) A. Wakkach et al.   BLOOD

Infantile Malignant, Autosomal Recessive Osteopetrosis: The Rich and The Poor

(2008) Anna Villa et al.   CALCIFIED TISSUE INTERNATIONAL