Editorial Material
Medicine, General & Internal
Elizabeth E. Krans
Summary: The opioid crisis in the United States has had significant impacts on pregnant individuals and their children. The rate of opioid-related diagnoses during pregnancy has been consistently rising across all states and demographic groups, and overdose has become a leading cause of pregnancy-related deaths. Treatment with medications like methadone and buprenorphine is recommended to reduce the risks of overdose and preterm birth for pregnant individuals with opioid use disorder.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Nutrition & Dietetics
Maria-Jose Castro, Jose-Maria Jimenez, Maria Lopez, Maria-Jose Cao, Gilberto Gonzalez-Ramirez, Maria de Lourdes Bolanos-Munoz, Jaime Ruiz-Tovar
Summary: This study compared the analytical and densitometric changes 2 years after RYGB and SG. The results showed no significant difference in weight loss between the two procedures. However, the RYGB group had a significantly greater increase in PTH values and a greater decrease in bone mineral density compared to the SG group.
Article
Endocrinology & Metabolism
Xueyao Xi, Yanan Gao, Jiaqi Wang, Nan Zheng
Summary: This study investigates the changes in bone mass following Sr intervention in young individuals and the connection between Sr-altered intestinal flora and potentially beneficial bacteria in the attenuation of bone loss. The findings highlight the importance of the gut-bone axis and provide a fresh insight into bone mass accumulation in young individuals and the prevention of disease due to acquired bone mass deficiency.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Pharmacology & Pharmacy
Suzanne Arends, Freke Wink, Joyce Veneberg, Reinhard Bos, Eric van Roon, Eveline van der Veer, Fiona Maas, Anneke Spoorenberg
Summary: This study suggests that 2-year treatment with bisphosphonates in combination with calcium/vitamin D supplements significantly improves lumbar spine BMD in AS patients, but mild radiographic vertebral fractures still occurred.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2021)
Article
Pharmacology & Pharmacy
Zhixin Wu, Yinxian Wen, Hao Xiao, Jiayong Zhu, Bin Li, Yangfan Shangguan, Hangyuan He, Hui Wang, Liaobin Chen
Summary: Epidemiological investigations have shown an increased risk of osteoporosis in individuals treated with dexamethasone during pregnancy. Decreased peak bone mass and increased bone local active corticosterone were observed in prenatal dexamethasone exposure (PDE) offspring, with further decrease and increase after chronic stress. Injection of 118-HSD2 overexpression lentivirus partially alleviated bone loss induced by PDE. Dexamethasone inhibited 118HSD2 expression and aggravated the inhibitory effect of corticosterone on osteogenic differentiation, while overexpression of 118-HSD2 partially alleviated this effect.
PHARMACOLOGICAL RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Kalpana Patel, S. V. V. S. Ravi Mangu, Shinde Vijay Sukhdeo, Kunal Sharan
Summary: This study investigates the effects of sesamol on bone metabolism. It found that sesamol can promote bone formation but can also lead to bone deterioration in ovariectomized rats. These findings highlight the potential negative impact of sesamol in postmenopausal women.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2023)
Article
Orthopedics
Keith A. Knurr, Stephanie A. Kliethermes, Colten R. Haack, Justin S. Olson, Neil C. Binkley, Tamara A. Scerpella, Bryan C. Heiderscheit
Summary: This study evaluated the bilateral changes in femur and tibia bone mineral density (BMD) in collegiate athletes before and after ACL reconstruction. The results showed that BMD deficits persisted at the distal femur of the surgical limb 24 months after ACLR. However, there were no significant differences in other regions of both limbs.
AMERICAN JOURNAL OF SPORTS MEDICINE
(2022)
Article
Medicine, General & Internal
Diane Chen, Johnny Berona, Yee-Ming Chan, Diane Ehrensaft, Robert Garofalo, Marco A. Hidalgo, Stephen M. Rosenthal, Amy C. Tishelman, Johanna Olson-Kennedy
Summary: In this prospective study of transgender and nonbinary youth in the United States, researchers found that gender-affirming hormones (GAH) improved appearance congruence and psychosocial functioning, while reducing depression and anxiety symptoms.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Nutrition & Dietetics
Tiffany Dodier, Kendall L. Anderson, James Bothwell, Janice Hermann, Edralin A. Lucas, Brenda J. Smith
Summary: Preclinical studies have shown that tart cherries protect against age-related and inflammation-induced bone loss. This study found that daily consumption of Montmorency tart cherry juice can reduce bone resorption without affecting bone formation and turnover biomarkers in older women.
Article
Biology
Yupeng Liu, Siyu Le, Yi Liu, Huinan Jiang, Binye Ruan, Yufeng Huang, Xuemei Ao, Xudong Shi, Xiaoyi Fu, Shuran Wang
Summary: This systematic review and meta-analysis examined the effects of calcium supplementation on bone mineral accretion in young populations. The findings suggest that calcium supplementation has a significant positive impact on bone density and mass, particularly in the femoral neck and total body. Interestingly, the improvement in bone mass at the femoral neck was more pronounced in the population aged 20-35 years.
Article
Endocrinology & Metabolism
Jingzheng Fan, Yuyan Jiang, Junlian Qiang, Bin Han, Qiang Zhang
Summary: This study investigated the relationship between body fat accumulation, fat distribution, and bone mineral density in non-obese postmenopausal women. The results showed a positive association between total fat mass and bone mineral density, while fat distribution had a negative correlation with bone mineral density.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Oncology
H. van Baar, M. J. L. Bours, S. Beijer, M. van Zutphen, F. J. B. van Duijnhoven, D. E. Kok, E. Wesselink, J. H. W. de Wilt, E. Kampman, R. M. Winkels
Summary: Persistent fatigue among colorectal cancer patients may be associated with body composition, with higher SAT levels at diagnosis and lower SMR levels at 6 months post-diagnosis correlating with more fatigue.
JOURNAL OF CANCER SURVIVORSHIP
(2021)
Article
Agriculture, Multidisciplinary
Jian Zhang, Yanfei Han, Miao Song, Qi Wang, Zheng Cao, Xu Yang, Yanfei Li
Summary: Se can significantly alleviate cytopenia and splenic extramedullary hematopoiesis caused by the T-2 toxin. Moreover, Se can improve T-2 toxin-induced immunosuppression, oxidative stress, apoptosis, and bone marrow microenvironment. Therefore, Se improves BM-related hematopoiesis and immunity after T-2 toxin exposure.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Public, Environmental & Occupational Health
Shuna Li, Li Li, Aozi Feng, Tao Huang, Chong Chen, Ningxia He, Liying Huang, Jun Lyu
Summary: This study found a positive association between hypertension and lumbar bone mineral density in both males older than 50 years and postmenopausal females. However, a similar pattern was not found in the femoral neck.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Oncology
Evangelos Terpos, Ioannis Ntanasis-Stathopoulos, Efstathios Kastritis, Evdoxia Hatjiharissi, Eirini Katodritou, Evangelos Eleutherakis-Papaiakovou, Evgenia Verrou, Maria Gavriatopoulou, Alexandros Leonidakis, Kyriaki Manousou, Sosana Delimpasi, Panagiotis Malandrakis, Marie-Christine Kyrtsonis, Maria Papaioannou, Argiris Symeonidis, Meletios-Athanasios Dimopoulos
Summary: The study demonstrates that the anti-CD38 monoclonal antibody daratumumab improves bone turnover in patients with multiple myeloma by inducing bone formation and reducing osteoblast inhibition, highlighting its clinical significance.
