Mouse Models ofEscherichia coliO157:H7 Infection and Shiga Toxin Injection

Escherichia coli O157:H7-secreted cytotoxins are toxic to enterocytes and increase Escherichia coli O157:H7 colonization of jejunum and descending colon in cattle

(2011) Danica Baines et al.   CANADIAN JOURNAL OF ANIMAL SCIENCE

Human Intestinal Tissue and Cultured Colonic Cells Contain Globotriaosylceramide Synthase mRNA and the Alternate Shiga Toxin Receptor Globotetraosylceramide

(2010) S. D. Zumbrun et al.   INFECTION AND IMMUNITY

Ingested Shiga Toxin 2 (Stx2) Causes Histopathological Changes in Kidney, Spleen, and Thymus Tissues and Mortality in Mice

(2010) Reuven Rasooly et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Pathogenesis of Escherichia coli O157:H7 strain 86-24 following oral infection of BALB/c mice with an intact commensal flora

(2010) Krystle L. Mohawk et al.   MICROBIAL PATHOGENESIS

Neutralizing antibodies to Shiga toxin type 2 (Stx2) reduce colonization of mice by Stx2-expressing Escherichia coli O157:H7

(2010) Krystle L. Mohawk et al.   VACCINE

A DNA Vaccine Encoding the Enterohemorragic Escherichia coli Shiga-Like Toxin 2 A2 and B Subunits Confers Protective Immunity to Shiga Toxin Challenge in the Murine Model

(2009) L. V. Bentancor et al.   Clinical and Vaccine Immunology

A Randomized Longitudinal Trial to Test the Effect of Regional Vaccination Within a Cattle Feedyard on Escherichia coli O157:H7 Rectal Colonization, Fecal Shedding, and Hide Contamination

(2009) David R. Smith et al.   Foodborne Pathogens and Disease

Efficacy of Escherichia coli O157:H7 Siderophore Receptor/Porin Proteins–Based Vaccine in Feedlot Cattle Naturally Shedding E. coli O157

(2009) J. Trent Fox et al.   Foodborne Pathogens and Disease

Use of a Siderophore Receptor and Porin Proteins-Based Vaccine to Control the Burden of Escherichia coli O157:H7 in Feedlot Cattle

(2009) Daniel U. Thomson et al.   Foodborne Pathogens and Disease

Escherichia coli O157:H7 Vaccine Dose–Effect in Feedlot Cattle

(2009) Rodney A. Moxley et al.   Foodborne Pathogens and Disease

Shiga Toxin 2 Targets the Murine Renal Collecting Duct Epithelium

(2009) M. A. Psotka et al.   INFECTION AND IMMUNITY

Shiga toxin Stx2 is heat-stable and not inactivated by pasteurization

(2009) Reuven Rasooly et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Enterohemorrhagic Escherichia coli trivalent recombinant vaccine containing EspA, intimin and Stx2 induces strong humoral immune response and confers protection in mice

(2009) Jiang Gu et al.   MICROBES AND INFECTION

Shiga toxins — from cell biology to biomedical applications

(2009) Ludger Johannes et al.   NATURE REVIEWS MICROBIOLOGY

Immunogenicity of a novel Stx2B–Stx1B fusion protein in a mice model of Enterohemorrhagic Escherichia coli O157:H7 infection

(2009) Xiang Gao et al.   VACCINE

Shiga Toxin-Mediated Disease in MyD88-Deficient Mice Infected with Escherichia coli O157:H7

(2008) Carla Calderon Toledo et al.   AMERICAN JOURNAL OF PATHOLOGY

Early Attachment Sites for Shiga-Toxigenic Escherichia coli O157:H7 in Experimentally Inoculated Weaned Calves

(2008) E. A. Dean-Nystrom et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Renal damage and death in weaned mice after oral infection with Shiga toxin 2-producingEscherichia colistrains

(2008) R. J. F. Brando et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Pathogenesis of Renal Disease Due to Enterohemorrhagic Escherichia coli in Germ-Free Mice

(2008) K. A. Eaton et al.   INFECTION AND IMMUNITY

Mouse Model of Hemolytic-Uremic Syndrome Caused by Endotoxin-Free Shiga Toxin 2 (Stx2) and Protection from Lethal Outcome by Anti-Stx2 Antibody

(2008) K. A. D. Sauter et al.   INFECTION AND IMMUNITY

Shiga Toxin 2 Affects the Central Nervous System through Receptor Globotriaosylceramide Localized to Neurons

(2008) Fumiko Obata et al.   JOURNAL OF INFECTIOUS DISEASES

Subcutaneous and intranasal immunization with type III secreted proteins can prevent colonization and shedding of Escherichia coli O157:H7 in mice

(2008) Shawn Babiuk et al.   MICROBIAL PATHOGENESIS

Development of an experimental hemolytic uremic syndrome in rats

(2008) Elsa Zotta et al.   PEDIATRIC NEPHROLOGY

Variation in virulence among clades of Escherichia coli O157:H7 associated with disease outbreaks

(2008) S. D. Manning et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA