Parasitic Helminths: New Weapons against Immunological Disorders

Helminth Infection with Litomosoides sigmodontis Induces Regulatory T Cells and Inhibits Allergic Sensitization, Airway Inflammation, and Hyperreactivity in a Murine Asthma Model

(2014) A. M. Dittrich et al.   JOURNAL OF IMMUNOLOGY

Colonization with Heligmosomoides polygyrus Suppresses Mucosal IL-17 Production

(2014) D. E. Elliott et al.   JOURNAL OF IMMUNOLOGY

Taenia crassicepsInfection Attenuates Multiple Low-Dose Streptozotocin-Induced Diabetes

(2010) Arlett Espinoza-Jiménez et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

IgE cross-reactivity betweenAscarisand domestic mite allergens: the role of tropomyosin and the nematode polyprotein ABA-1

(2009) N. Acevedo et al.   ALLERGY

Reduced helminth burden increases allergen skin sensitization but not clinical allergy: a randomized, double-blind, placebo-controlled trial in Vietnam

(2009) C. Flohr et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Do helminth parasites protect against atopy and allergic disease?

(2009) C. Flohr et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells

(2009) Natalia Martin-Orozco et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Schistosoma mansoniegg antigens induce Treg that participate in diabetes prevention in NOD mice

(2009) Paola Zaccone et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Helminth Infection Can Reduce Insulitis and Type 1 Diabetes through CD25- and IL-10-Independent Mechanisms

(2009) Q. Liu et al.   INFECTION AND IMMUNITY

Infection withHymenolepis diminutaIs More Effective than Daily Corticosteroids in Blocking Chemically Induced Colitis in Mice

(2009) Alexandra Melon et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice

(2009) David Bending et al.   JOURNAL OF CLINICAL INVESTIGATION

T-bet is essential for encephalitogenicity of both Th1 and Th17 cells

(2009) Yuhong Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Infection with a Helminth Parasite Attenuates Autoimmunity through TGF- -Mediated Suppression of Th17 and Th1 Responses

(2009) K. P. Walsh et al.   JOURNAL OF IMMUNOLOGY

Human Type 1 and 17 Responses in Latent Tuberculosis Are Modulated by Coincident Filarial Infection through Cytotoxic T Lymphocyte Antigen–4 and Programmed Death–1

(2009) Subash Babu et al.   JOURNAL OF INFECTIOUS DISEASES

A protective function for interleukin 17A in T cell–mediated intestinal inflammation

(2009) William O'Connor Jr et al.   NATURE IMMUNOLOGY

Type 17 T helper cells—origins, features and possible roles in rheumatic disease

(2009) Francesco Annunziato et al.   Nature Reviews Rheumatology

Can helminths or helminth-derived products be used in humans to prevent or treat allergic diseases?

(2009) Klaus J. Erb   TRENDS IN IMMUNOLOGY

The therapeutic helminth?

(2009) Derek M. McKay   TRENDS IN PARASITOLOGY

Alternative Activation of Macrophages: An Immunologic Functional Perspective

(2008) Fernando O. Martinez et al.   Annual Review of Immunology

Cytokine-controlled RANKL and osteoprotegerin expression by human and mouse synovial fibroblasts: Fibroblast-mediated pathologic bone resorption

(2008) Miklos Tunyogi-Csapo et al.   ARTHRITIS AND RHEUMATISM

Infection with the roundworm Toxocara canis leads to exacerbation of experimental allergic airway inflammation

(2008) E. Pinelli et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Ascaris lumbricoides-induced suppression of total and specific IgE responses in atopic subjects is interleukin 10-independent and associated with an increase of CD25+ cells

(2008) Giovanni Matera et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages

(2008) Sheila Donnelly et al.   FASEB JOURNAL

The immunomodulatory glycan LNFPIII initiates alternative activation of murine macrophagesin vivo

(2008) Olga Atochina et al.   IMMUNOLOGY

Inhibition of type 1 diabetes in filaria-infected non-obese diabetic mice is associated with a T helper type 2 shift and induction of FoxP3+regulatory T cells

(2008) Marc P. Hübner et al.   IMMUNOLOGY

Hookworm-Induced Persistent Changes to the Immunological Environment of the Lung

(2008) J. J. Reece et al.   INFECTION AND IMMUNITY

Protective Effect of an Extract from Ascaris suum in Experimental Arthritis Models

(2008) F. A. C. Rocha et al.   INFECTION AND IMMUNITY

Therapeutic potential of helminth soluble proteins in TNBS-induced colitis in mice

(2008) Nathalie E. Ruyssers et al.   INFLAMMATORY BOWEL DISEASES

Schistosoma mansoni infection reduces severity of collagen-induced arthritis via down-regulation of pro-inflammatory mediators

(2008) Yoshio Osada et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Soluble egg antigen from Schistosoma japonicum modulates the progression of chronic progressive experimental autoimmune encephalomyelitis via Th2-shift response

(2008) Xueping Zheng et al.   JOURNAL OF NEUROIMMUNOLOGY

Peroxiredoxin-1 from Schistosoma japonicum functions as a scavenger against hydrogen peroxide but not nitric oxide

(2008) Takashi Kumagai et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

An update on the use of helminths to treat Crohn’s and other autoimmunune diseases

(2008) Aditya Reddy et al.   PARASITOLOGY RESEARCH

Th17 Cells and Autoimmune Encephalomyelitis (EAE/MS)

(2008) Toshimasa Aranami et al.   ALLERGOLOGY INTERNATIONAL

Trichinella spiralis: Modulation of experimental autoimmune encephalomyelitis in DA rats

(2007) A. Gruden-Movsesijan et al.   EXPERIMENTAL PARASITOLOGY

Interplay of parasite-driven immune responses and autoimmunity

(2007) Paola Zaccone et al.   TRENDS IN PARASITOLOGY